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Found 40 with Last Name = 'zheng' and Initial = 'qh'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50510071(CHEMBL4541082)
Affinity DataKi:  1.90nMAssay Description:Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50510072(CHEMBL4435339)
Affinity DataKi:  2.5nMAssay Description:Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataKi:  3.10nMAssay Description:Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]ketanserin from 5-HT2A receptor in human frontal cortex after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308541(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308537(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  6.92nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308538(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  9.37nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308539(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  10.3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]raclopride from D2 receptor in human corpus striatum after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]mesulergine from 5-HT2C receptor in human frontal cortex after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308546(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi:  23.8nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308540(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  27.9nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50510070(CHEMBL2218191)
Affinity DataKi:  54nMAssay Description:Competitive displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintill...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308537(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  196nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308539(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  323nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308542(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi:  497nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308540(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  733nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308543(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308544(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308545(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi:  1.33E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308546(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi:  2.88E+3nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308545(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308543(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308542(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308541(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308538(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50308544(2-Chloro-7-methoxy-8-pentyloxy-1-quinoline-3-carbo...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50510071(CHEMBL4541082)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]ketanserin from 5-HT2A receptor in human frontal cortex after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50510072(CHEMBL4435339)
Affinity DataIC50:  7.10nMAssay Description:Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...)
Affinity DataIC50:  8nMAssay Description:Inhibition of matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]raclopride from D2 receptor in human corpus striatum after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataIC50:  71nMAssay Description:Displacement of [3H]mesulergine from 5-HT2C receptor in human frontal cortex after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetP2X purinoceptor 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50510070(CHEMBL2218191)
Affinity DataIC50:  153nMAssay Description:Displacement of [11C]GSK1482160 from human recombinant P2X7 receptor expressed in HEK293 cell membranes incubated for 30 mins by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50084289((S)-2-(4'-methoxy-biphenyl-4-sulfonylamino)-3-meth...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed