Affinity DataKi: 40nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2.03E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.43E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.123nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 0.124nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arre...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arre...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Tested in vitro for inhibition of chymotrypsin like activity of purified human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Tested in vitro for inhibition of chymotrypsin like activity of purified human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Tested in vitro for inhibition of chymotrypsin like activity of purified human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Cyclin-dependent kinase 1, CDK1-related human bladder carcinoma (T24) cell protliferationMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Tested in vitro for inhibition of chymotrypsin like activity of purified human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair