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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
Niigata College of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Ki: 12.0nM
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Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
Niigata College of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Ki: 67.6nM
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM50470811
(Dilevalol)
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Affinity Data
Ki: 295nM
Assay Description:
Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Niigata College of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Ki: 2.00E+3nM
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Target
Dipeptidyl peptidase 3
(Bos mutus)
Kurukshetra University
Curated by
ChEMBL
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Ki: 2.80E+5nM
Assay Description:
Competitive inhibition of Capra hircus (goat) brain DPP-3 using Arg-Arg-4mbetaNA as substrate assessed as liberation of 4mbetaNA from substrate prein...
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Target
Dipeptidyl peptidase 3
(Bos mutus)
Kurukshetra University
Curated by
ChEMBL
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
IC50: 3.60E+5nM
Assay Description:
Inhibition of Capra hircus (goat) brain DPP-3 using Arg-Arg-4mbetaNA as substrate assessed as liberation of 4mbetaNA from substrate
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Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
IC50: 6.49E+5nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
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Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Kd: 9.30nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
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Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Kd: 23.5nM
pH: 7.4 T: 2°C
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
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Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Kd: 661nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
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Target Info
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Target
Heparanase
(Homo sapiens (Human))
Centro De Investigaci�N Pr�Ncipe Felipe
Curated by
ChEMBL
Ligand
BDBM25758
(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
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Affinity Data
Kd: 1.00E+6nM
Assay Description:
Binding affinity to recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance assa...
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Target Info
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