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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50016504
((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
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Affinity Data
Ki: 0.150nM
Assay Description:
Tested for the inhibition of [3H]-pCCK-8 binding to Cholecystokinin type B receptor in guinea pig brain
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
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Target
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor
(Mus musculus)
TBA
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Affinity Data
Ki: 0.191nM
Assay Description:
Binding affinity measured by inhibiting [3H]Boc[Nle28,31]CCK27-33 specific binding to Cholecystokinin receptor in mouse brain membranes at a KD conce...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
KEGG
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Article
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Target
Cholecystokinin receptor type A
(Cavia porcellus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016504
((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
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Affinity Data
Ki: 0.230nM
Assay Description:
The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Affinity Data
Ki: 0.230nM
Assay Description:
Displacement of 0.2 nM [3H]-pCCK-8 from guinea pig brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A
(Cavia porcellus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016504
((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
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Affinity Data
Ki: 0.310nM
Assay Description:
Ability to displace 1 nM [3H]pCCK-8 from Cholecystokinin type A receptor in guinea pig pancreatic membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A
(Cavia porcellus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Copy InChI
Affinity Data
Ki: 0.930nM
Assay Description:
Displacement of 0.1 nM [3H]-pCCK-8 from guinea pig pancreatic membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A
(Cavia porcellus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016504
((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.930nM
Assay Description:
The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig pancreatic membrane
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Copy InChI
Affinity Data
Ki: 4.30nM
Assay Description:
Evaluated for binding affinity measured by inhibiting [3H]Boc[Nle28,31]CCK27-33 specific binding to Cholecystokinin receptor in rat pancreas membrane...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A
(Cavia porcellus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016504
((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 78nM
Assay Description:
Tested for the inhibition of [3H]-pCCK-8 binding to Cholecystokinin type A receptor in pancreatic membranes of guinea-pig
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Gastrin/cholecystokinin type B receptor
(RAT)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016504
((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
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Affinity Data
Ki: 96nM
Assay Description:
Ability to displace 1 nM [3H]pCCK-8 from rat Cholecystokinin type B receptor stably expressing in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Copy InChI
Affinity Data
IC50: 0.200nM
Assay Description:
Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from jurkat Tcells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.290nM
Assay Description:
In vitro binding affinity against Cholecystokinin type B receptor in guinea pig brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.290nM
Assay Description:
Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from guinea pig brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human))
Centre De Pharmacologie-Endocrinologie (Montpellier, France)
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Copy InChI
Affinity Data
IC50: 0.300nM
Assay Description:
Ability of compound to Inhibit the binding of [125I]BH-CCK-8 to Cholecystokinin receptor in isolated guinea pig brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A
(Cavia porcellus)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.930nM
Assay Description:
In vitro ability to inhibit [3H]propionyl-CCK-8 binding to Cholecystokinin type A receptor in guinea pig pancreas
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor
(RAT)
Centre De Pharmacologie-Endocrinologie (Montpellier, France)
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
Ability of compound to Inhibit the binding of [125I]BH-CCK-8 to Cholecystokinin receptor in isolated rat pancreatic acini
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Gastrin/cholecystokinin type B receptor
(RAT)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30nM
Assay Description:
In vitro binding affinity against Cholecystokinin type B receptor of rat pancreatic acini
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Gastrin/cholecystokinin type B receptor
(RAT)
University Of Paris
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30nM
Assay Description:
Inhibition of [125I]-BH-CCK- binding to peripheral cholecystokinin type B receptor from rat pancreatic acini
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Pancreatic alpha-amylase
(Homo sapiens (Human))
Ep Cnrs 51
Curated by
ChEMBL
Ligand
BDBM50016425
((S)-3-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-tert-Butoxyca...)
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Affinity Data
EC50: 0.0500nM
Assay Description:
Tested in vitro for amylase release from rat pancreatic acini
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI