Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
93
hits in this display
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Neurogastrx
US Patent
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 16nM
Assay Description:
The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Neurogastrx
US Patent
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 16nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 19nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Neurogastrx
US Patent
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 35nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 64nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 64nM
Assay Description:
The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
US Patent
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Sandoz Pharma
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 80nM
Assay Description:
Compound was evaluated for the binding affinity at Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 104nM
Assay Description:
Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 104nM
Assay Description:
Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 113nM
Assay Description:
Binding affinity to dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 158nM
Assay Description:
Tested for its binding affinity by measuring its ability to displace [3H]granisetron from 5-hydroxytryptamine 3 receptor in rat cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 200nM
Assay Description:
Binding affinity to 5-hydroxytryptamine 3 receptor entirely in guinea pig ileum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 205nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 210nM
Assay Description:
Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 229nM
Assay Description:
Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heart
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 235nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 240nM
Assay Description:
Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 285nM
Assay Description:
Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 303nM
Assay Description:
Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 348nM
Assay Description:
Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 353nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 443nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 443nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Alpha-2C adrenergic receptor
(RAT)
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 452nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 490nM
Assay Description:
Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 501nM
Assay Description:
pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 501nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 501nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 502nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 546nM
Assay Description:
Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 631nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 631nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(MOUSE)
Cnrs Upr 9023
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 891nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 900nM
Assay Description:
Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 960nM
Assay Description:
Mechanism based inhibition of human cytochrome P450 2D6 measured by dextromethorphan O-demethylation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 974nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 975nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]-GR-113,808 as radioligand in rat striatum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 995nM
Assay Description:
Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.06E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.86E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(MOUSE)
Cnrs Upr 9023
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.98E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(MOUSE)
Cnrs Upr 9023
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.98E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(RAT)
Case Western Reserve University
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
U. 109
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(RAT)
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(RAT)
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
6-phosphogluconate dehydrogenase, decarboxylating
(Homo sapiens (Human))
Ataturk University
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.11E+6nM IC50: 3.27E+6nM
Assay Description:
In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Dainippon Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 61.3nM
Assay Description:
Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatum
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
It is well-known that drug compounds that have an affinity for the striatal dopamine D2 may give rise to adverse side effects, such as short-term ext...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
US Patent
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 228nM
Assay Description:
Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 280nM
Assay Description:
The functional antagonist assay was performed as described in Payne, S. L et al. (2002) J. Neurochem., 82: 1106-1117, hereby incorporated by referenc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
US Patent
DrugBank
Copy BDB DOI
Target
Myeloperoxidase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 444nM
Assay Description:
Concentration of compound required to inhibit the binding of radioligand [3H]spiperone to Dopamine receptor D2 in rat brain synaptic membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 480nM
Assay Description:
Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 480nM
Assay Description:
Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 565nM
Assay Description:
In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 630nM
Assay Description:
Inhibitory activity against dopamine receptor D2 by 3H ligand binding experiments.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Astra LÄKemedel
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 820nM
Assay Description:
Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 880nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 880nM
Assay Description:
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 912nM
Assay Description:
Concentration of compound required to inhibit the binding of radioligand [3H]GR-113808 to serotonin 5-hydroxytryptamine 4 receptor in guinea-pig stri...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Myeloperoxidase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lactoperoxidase
(Bos taurus (Bovine))
Universit£
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT)
Dainippon Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.70E+3nM
Assay Description:
Inhibitory activity against alpha-2 adrenergic receptor by 3H ligand binding experiments.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A/1B/1D/1F
(RAT)
Dainippon Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.80E+3nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 1 receptor by 3H ligand binding experiments.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serotonin 2 (5-HT2) receptor
(RAT)
Dainippon Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.32E+4nM
Assay Description:
Inhibitory activity against 5-hydroxytryptamine 2 receptor by 3H ligand binding experiments.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of guinea pig acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Dainippon Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.28E+4nM
Assay Description:
Inhibitory activity against Alpha-1 adrenergic receptor by 3H ligand binding experiments.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Estrogen receptor beta
(Homo sapiens (Human))
Emory University
Curated by
PubChem BioAssay
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.00E+4nM
Assay Description:
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Solute carrier family 22 member 1
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.48E+4nM
Assay Description:
Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.35E+5nM
Assay Description:
Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A/3B
(Mus musculus (house mouse))
Merrell Dow Research Institute
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 224nM
Assay Description:
Potency to 5-hydroxytryptamine 3 receptor entirely in guinea pig ileum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 794nM
Assay Description:
Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosae
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
TBA
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 794nM
Assay Description:
Agonist activity against 5-HT4 receptor in rat esophageal muscularis mucosae
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
University of Alberta
Curated by
PDSP K
i
Database
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.70nM
Assay Description:
5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Albumin
(Rattus norvegicus)
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.37E+6nM
Assay Description:
Binding affinity to Wistar rat serum albumin
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM48320
(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.92E+3nM
Assay Description:
Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Displayed 1 to 50 (of 93 total ) |
Next
|
Last
>>