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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
116
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Target
Type-1 angiotensin II receptor A
(RAT)
TBA
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 0.230nM
Assay Description:
Displacement of [125I]-SI-Ang-2 from AT1 receptor in Rattus norvegicus Sprague-Dawley (rat) liver membranes after 2 hr
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 8nM ΔG°: -43.0kJ/mole
pH: 8.2 T: 2°C
Assay Description:
Binding assays were performed in 96-well plate format, using a classical filtration assay with a human full length PPARγ construct (GST-PPAR LBD...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 17nM
Assay Description:
Binding affinity to GST-tagged PPARG LBD (unknown origin) by Fluormone Pan-PPAR Green tracer based TR-FRET assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 26nM
Assay Description:
Displacement of [3H]rosiglitazone from human PPAR-gamma incubated for 1 day by radioligand binding assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 27nM
Assay Description:
Agonist activity at PPARgamma ligand binding domain (unknown origin) using fluormone Pan-PPAR green tracer by TR-FRET assay based competitive ligand ...
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Target
CDGSH iron-sulfur domain-containing protein 1
(Homo sapiens (Human))
West Virginia University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 31nM
Assay Description:
Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 47nM
Assay Description:
Binding affinity against Peroxisome proliferator activated receptor gamma (PPAR gamma)
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Ki: 59nM
Assay Description:
Displacement of fluormone PPAR green tracer ligand from recombinant GST-tagged PPARgamma ligand binding domain (unknown origin) incubated for 4 hrs b...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 7.70nM
Assay Description:
Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as displacement of SMRT incubated for 16 hrs by luciferase reporter...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 10nM
Assay Description:
Displacement of [3H]rosiglitazone from human recombinant PPARgamma receptor expressed in Escherichia coli
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 10nM
Assay Description:
Displacement of [3H]rosiglitazone from human recombinant PPAR-gamma receptor expressed in Escherichia coli measured after 120 mins by scintillation c...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 38nM
Assay Description:
Binding affinity to GST-tagged human PPAR-gamma receptor by FRET assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 76nM
Assay Description:
Agonist activity at PPARgamma ligand binding domain (unknown origin) using fluormone Pan-PPAR green tracer by TR-FRET assay based competitive ligand ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 76nM
Assay Description:
Displacement of fluormone PPAR green tracer ligand from recombinant GST-tagged PPARgamma ligand binding domain (unknown origin) incubated for 4 hrs b...
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Target
Peroxisome proliferator-activated receptor alpha
(Mus musculus)
Terns Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 80nM
Assay Description:
Activation of mouse liver PPARalpha
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 88nM
Assay Description:
Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as displacement of NCoR incubated for 16 hrs by luciferase reporter...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 90nM
Assay Description:
Binding affinity to PPARgamma (unknown origin) by lanthascreen TR-FRET assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 103nM
Assay Description:
Inhibition of fluormone PPARgamma Green binding to recombinant N-terminal GST-tagged human PPARgamma LBD by fluorescence polarization assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 112nM
Assay Description:
Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...
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Target
Nuclear receptor coactivator 2 [740-753]
()
Metabolic Solutions Development
US Patent
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 125nM
Assay Description:
PPARγ binding is measured by a TR-FRET competitive binding assay using Invitrogen LanthaScreen TR-FRET PPARγ Competitive Binding Assay (I...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 159nM
Assay Description:
Displacement of fluormone from human PPARgamma LBD expressed in Escherichia coli BL21 DE3 by fluorescence polarization assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 292nM
Assay Description:
Displacement of fluormone-PPARgamma Green from recombinant human N-terminal GST-tagged PPARgamma-LBD by fluorescence polarization assay
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Target Info
PDB
MMDB
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 298nM
Assay Description:
Displacement of fluormone-PPARgamma green from GST-tagged PPARgamma-LBD (unknown origin) by fluorescence polarization assay
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PDB
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Target
CDGSH iron-sulfur domain-containing protein 1
(Homo sapiens (Human))
West Virginia University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 731nM
Assay Description:
Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...
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Target
Amine oxidase [flavin-containing] B
(Homo sapiens (Human))
Comsats University Islamabad
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 832nM
Assay Description:
Inhibition of recombinant human MAO-B
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Target
CDGSH iron-sulfur domain-containing protein 1
(Rattus norvegicus)
Northeastern Ohio Universities
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Displacement of [3H]rosiglitazone from rat liver mitochondrial mitoNEET by scintillation counting
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CDGSH iron-sulfur domain-containing protein 2
(Homo sapiens)
West Virginia University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 2.29E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal His6-tagged NAF1 expressed in Escherichia coli by scintillation proximity assay
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 3.75E+3nM
Assay Description:
Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 3.80E+3nM
Assay Description:
Inhibition of human BSEP expressed in HEK293 cell membrane vesicles assessed as reduction in 3H-TCA uptake incubated for 5 mins by radiodetection met...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 4.40E+3nM
Assay Description:
Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 4.40E+3nM
Assay Description:
Inhibition of PPARgamma (unknown origin) phosphorylation at pS273 residue
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Target
Sodium/bile acid cotransporter
(Homo sapiens (Human))
Southwest Jiaotong University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 5.10E+3nM
Assay Description:
Inhibition of HA-tagged human NTCP expressed in human U2OS cells assessed as reduction in [14C]taurocholate uptake preincubated for 10 mins followed ...
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Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 6.36E+3nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
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Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 6.40E+3nM
Assay Description:
Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 2.10E+4nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 2.20E+4nM
Assay Description:
Transrepression activity at human PPARgamma expressed in HEK293 cells assessed as inhibition of TNFalpha induced NF-kappaB promoter activity pretreat...
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Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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IC50: 2.95E+4nM
Assay Description:
Inhibition of human ERG expressed in CHO cells by patch clamp assay
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Bile salt export pump
(Rattus norvegicus)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: 4.00E+4nM
Assay Description:
Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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IC50: 6.00E+4nM
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Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
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Target
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human))
TBA
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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IC50: 4.00E+5nM
Assay Description:
Inhibition of PTP1B (unknown origin)
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 280nM
Assay Description:
Agonist activity at human PPARgamma expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at GAL4-tagged human PPAR receptor
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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EC50: 260nM
Assay Description:
Agonist activity at N-terminal Gal4 fused human PPARgamma LBD transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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EC50: 40nM
Assay Description:
Transactivation of GAL4-tagged human PPARgamma LBD expressed in human HepG2 cells at 100 nM to 100 uM incubated for 20 to 22 hrs by luciferase report...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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EC50: 259nM
Assay Description:
Transactivation of human PPARgamma transfected in U2OS cells co-tranfected with human RXR measured after 24 hrs by luciferase reporter assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at GAL4-tagged human PPAR receptor
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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EC50: 200nM
Assay Description:
Agonist activity at recombinant human PPARgamma LBD (205 to 505 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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EC50: 76nM
Assay Description:
Agonist activity at GAL4-tagged PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation incubated for ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Kd: 48nM
Assay Description:
Binding affinity to PPARg (unknown origin) by SPR assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 481nM
Assay Description:
Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as recruitment of TIF2 incubated for 16 hrs by luciferase reporter ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 297nM
Assay Description:
Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as recruitment of MED1 incubated for 16 hrs by luciferase reporter ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 156nM
Assay Description:
Agonist activity at human PPARgamma transfected in human HEK293 cells incubated for 18 hrs by Renilla/Firefly dual-luciferase reporter assay
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Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
University Of Toledo College Of Pharmacy And Pharmaceutical Sciences
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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EC50: 3.39E+3nM
Assay Description:
Agonist activity at human PPARalpha transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv...
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Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
University Of Toledo College Of Pharmacy And Pharmaceutical Sciences
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 8.89E+3nM
Assay Description:
Agonist activity at human PPARdelta transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv...
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Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 144nM
Assay Description:
Agonist activity at human PPARgamma transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 1.92E+5nM
Assay Description:
Agonist activity at human Gal4 fused PPARgamma LBD expressed in COS-7 cells incubated for 24 hrs by firefly luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 83nM
Assay Description:
Agonist activity at recombinant N-terminal His6 -tagged GFP fused PPARgamma LBD (unknown origin) (203 to 477 residues) expressed in Escherichia cell ...
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Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 169nM
Assay Description:
Agonist activity at PPARgamma (unknown origin)
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 100nM
Assay Description:
Partial agonist activity at sGSF-PPARgamma (unknown origin) assessed as CBP-1 recruitment by HT-FRET assay
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Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Kd: 3.30E+3nM
Assay Description:
Binding affinity to PPARgamma LBD (unknown origin) assessed as dissociation constant followed by heating for 3 mins by Bradford assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 26nM
Assay Description:
Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in FITC-labeled PGC-1alpha coactivator peptide recruitment by HTRF as...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 4.40E+4nM
Assay Description:
Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in FITC-labeled PGC-1alpha coactivator peptide recruitment in presenc...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 134nM
Assay Description:
Agonist activity at pBIND tagged human PPARgamma expressed in human HEK293 cells incubated for 18 hrs by dual luciferase reporter assay relative to c...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 40nM
Assay Description:
Agonist activity at yeast Gal4-fused human PPARgamma transfected in human HepG2 cells assessed as transactivation by measuring beta-galactosidase act...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 49nM
Assay Description:
Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 120nM
Assay Description:
Agonist activity at human PPARgamma measured by dual luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 27nM
Assay Description:
Agonist activity at Gal4-fused PPARgamma (unknown origin) expressed in human U2OS cells co-transfected with pSG5 expression vector preincubated for 4...
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Target
Platelet-derived growth factor receptor alpha/beta
(Mus musculus (mouse))
TBA
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Kd: 650nM
Assay Description:
Binding affinity to human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer assessed as dissociation constant ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 300nM
Assay Description:
Binding affinity to PPARgamma (unknown origin)
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 9nM
Assay Description:
Agonist activity at human PPARgamma transfected in HEK293 cells assessed increase in luciferase activity incubated for 24 hrs
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 730nM
Assay Description:
Agonist activity at GAL4-fused human PPARgamma expressed in HepG2 cells
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at PPAR-gamma in human BMMSC cells assessed as induction of adiponectin production in presence of IDX adipogenic induction medium an...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 1nM
Assay Description:
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...
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Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
University Of Toledo College Of Pharmacy And Pharmaceutical Sciences
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 5.25E+3nM
Assay Description:
After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 10nM
Assay Description:
Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase reporter gene assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Suez Canal University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 1.15E+4nM
Assay Description:
Agonist activity at FFAR1 (unknown origin) assessed as increase in ERK1/2 MAP kinase phosphorylation
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 39nM
Assay Description:
Agonist activity at human GAL4-PPARgamma ligand binding domain expressed in human HepG2 cells by luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor gamma
(Mus musculus)
Institute Of Chinese Materia Medica
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 30nM
Assay Description:
Agonist activity at mouse PPARgamma expressed in HEK293 cells co-expressing with Gal4 reporter vector after 24 hrs by dual-luciferase reporter assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 40nM
Assay Description:
Agonist activity at GAL4-DNA binding domain fused human PPARgamma ligand binding domain expressed in human HepG2 cells assessed as receptor transacti...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 87nM
Assay Description:
Agonist activity at human PPARgamma transfected in human MCF7 cells after 16 hrs by luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
University Of Toledo College Of Pharmacy And Pharmaceutical Sciences
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 240nM
Assay Description:
Transactivation of N-terminal Gal4 DNA binding domain-linked human PPARalpha ligand binding domain after 24 hrs by luciferase reporter gene assay rel...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 89nM
Assay Description:
Transcriptional activation of peroxisome proliferator activated receptor gamma
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 260nM
Assay Description:
Agonist activity at GAL4-tagged human PPARgamma ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter...
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Target
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human))
Xiamen University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Kd: 1.50E+4nM
Assay Description:
Binding affinity to RXRalpha-LBD (unknown origin) measured up to 120 sec by surface plasma resonance method
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 40nM
Assay Description:
Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
K
on
: 0.145M
-1
s
-1
Assay Description:
Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
Kd: 1.20nM
Assay Description:
Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 95nM
Assay Description:
Displacement of N-terminal biotin-labeled SMRT-ID1 (2339 to 2363 residues) from recombinant GST-tagged PPARgamma (unknown origin) expressed in Escher...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 52nM
Assay Description:
Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled LCOR (39 to ...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 117nM
Assay Description:
Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled NCoA3 (671 t...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 316nM
Assay Description:
Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled SRC1 (619 to...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 326nM
Assay Description:
Displacement of N-terminal biotin-labeled NCOR-ID1 (2253 to 2277 residues) from recombinant GST-tagged PPARgamma (unknown origin) expressed in Escher...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 114nM
Assay Description:
Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled NCoA3 (607 t...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 332nM
Assay Description:
Transactivation of recombinant GST-tagged PPARgamma (unknown origin) expressed in Escherichia coli assessed as N-terminal biotin-labeled PGC1alpha (1...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 300nM
Assay Description:
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 1.10E+3nM
Assay Description:
Transactivation activity at Gal4 fused full length human PPARgamma LBD expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 240nM
Assay Description:
Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 396nM
Assay Description:
Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 396nM
Assay Description:
Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
University Of Toledo College Of Pharmacy And Pharmaceutical Sciences
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 1.00E+4nM
Assay Description:
Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assay
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Copy BDB DOI
Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 4nM
Assay Description:
Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 39nM
Assay Description:
Transactivation of GAL4-tagged human PPARgamma LBD expressed in human HepG2 cells after 20 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 40nM
Assay Description:
Agonist activity at GAL4-fused PPARgamma LBD (unknown origin) expressed in HEK293 cells assessed as receptor transactivation after 18 hrs by dual luc...
More data for this Ligand-Target Pair
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 83nM
Assay Description:
Agonist activity at human PPARgamma after 22 to 24 hrs by luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor alpha/delta/gamma
(Homo sapiens (Human))
Yeungnam University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
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Affinity Data
EC50: 1.60E+3nM
Assay Description:
Transactivation of PPAR transfected in human HepG2 cells after 20 hrs by PPAR-luciferase assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 100nM
Assay Description:
Agonist activity at PPARgamma (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 120nM
Assay Description:
Agonist activity at human GAL4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 8nM
Assay Description:
Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor alpha/delta/gamma
(Homo sapiens (Human))
Yeungnam University
Curated by
ChEMBL
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 120nM
Assay Description:
Activation of PPAR in human HepG2 cells after 24 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 10nM
Assay Description:
Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in human HepG2 cells by transactivation assay
More data for this Ligand-Target Pair
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 20nM
Assay Description:
Transactivation activity at Homo sapiens (human) PPARgamma
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 4nM
Assay Description:
Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by lucifer...
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 210nM
Assay Description:
Partial agonist activity at recombinant N-terminal GFP-fused PPARgamma LBD (unknown origin) assessed as increase in biotinylated-CBP peptide recruitm...
More data for this Ligand-Target Pair
Target Info
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Universit?? De Rennes 1
Ligand
BDBM50030474
(Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...)
Copy SMILES
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Affinity Data
EC50: 115nM
Assay Description:
Partial agonist activity at recombinant N-terminal GFP-fused PPARgamma LBD (unknown origin) assessed as increase in biotinylated-SRC1 peptide recruit...
More data for this Ligand-Target Pair
Target Info
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