Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 42 hits in this display
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 1.80nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 2.63nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 120nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 130nMAssay Description:Inhibition of human N-terminal His6-tagged BRDT (21 to 137 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 1 hrMore data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 130nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 130nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 130nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 220nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 290nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 581nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 678nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 680nMAssay Description:AlphaScreen is a bead-based, non-radioactive Amplified Luminescent Proximity Homogeneous Assay. The details are not described in this patent.More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 736nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 790nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 1.40E+3nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
IC50: 1.40E+3nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Kd: 123nMAssay Description:Binding affinity to recombinant human His6-TEV protease-tagged BRD4 bromodomain 1 expressed in bacteria by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
BDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Kd: 123nMAssay Description:Binding affinity to human N-terminal His6-tagged BRDTexpressed in Escherichia coli BL21 (DE3) cells (21 to 137 residues) incubated for 1 hrMore data for this Ligand-Target Pair