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Found 70 Enz. Inhib. hit(s) with Target = 'Bromodomain testis-specific protein [22-138]'
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550507(US11306105, Compound 300)
Affinity DataIC50:  60nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562599(US11406645, Compound 502)
Affinity DataIC50:  61nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562619(US11406645, Compound 504)
Affinity DataIC50:  69nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562623(US11406645, Compound 505)
Affinity DataIC50:  75nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataIC50:  77nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataIC50:  77nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562570(US11406645, Compound 501)
Affinity DataIC50:  82nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM562610(US11406645, Compound 503)
Affinity DataIC50:  89nMAssay Description:Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550490(US11306105, Compound 106)
Affinity DataIC50:  105nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543481(US11279703, TABLE 6.351 | US11279703, TABLE 6.353 ...)
Affinity DataIC50:  118nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550487(US11306105, Compound 103)
Affinity DataIC50:  120nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550485(US11306105, Compound 101)
Affinity DataIC50:  120nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543570(US11279703, TABLE 6.159 | US11643396, Example SG4-...)
Affinity DataIC50:  131nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550496(US11306105, Compound 200)
Affinity DataIC50:  132nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550492(US11306105, Compound 108)
Affinity DataIC50:  133nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543479(US11279703, TABLE 6.289 | US11279703, TABLE 6.296 ...)
Affinity DataIC50:  140nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550493(US11306105, Compound 109)
Affinity DataIC50:  142nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543757(US11279703, TABLE 6.347)
Affinity DataIC50:  177nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)
Affinity DataIC50:  182nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataIC50:  183nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543776(US11279703, TABLE 6.366 | US11279703, TABLE 6.388)
Affinity DataIC50:  185nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543789(US11279703, TABLE 6.379 | US11279703, TABLE 6.380)
Affinity DataIC50:  185nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550491(US11306105, Compound 107)
Affinity DataIC50:  187nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543682(US11279703, TABLE 6.271)
Affinity DataIC50:  189nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543795(US11279703, TABLE 6.385 | US11279703, TABLE 6.386)
Affinity DataIC50:  194nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550494(US11306105, Compound 110)
Affinity DataIC50:  197nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550488(US11306105, Compound 104)
Affinity DataIC50:  216nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543791(US11279703, TABLE 6.381 | US11279703, TABLE 6.382)
Affinity DataIC50:  223nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543569(US11279703, TABLE 6.158 | US11279703, TABLE 6.169 ...)
Affinity DataIC50:  228nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.119 | US11279703, TABLE 6.128 ...)
Affinity DataIC50:  230nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543516(US11279703, TABLE 6.119 | US11279703, TABLE 6.128 ...)
Affinity DataIC50:  230nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543638(US11279703, TABLE 6.227)
Affinity DataIC50:  230nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543795(US11279703, TABLE 6.385 | US11279703, TABLE 6.386)
Affinity DataIC50:  268nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543701(US11279703, TABLE 6.290)
Affinity DataIC50:  268nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543797(US11279703, TABLE 6.387)
Affinity DataIC50:  281nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543776(US11279703, TABLE 6.366 | US11279703, TABLE 6.388)
Affinity DataIC50:  292nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543789(US11279703, TABLE 6.379 | US11279703, TABLE 6.380)
Affinity DataIC50:  302nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543756(US11279703, TABLE 6.346)
Affinity DataIC50:  308nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543677(US11279703, TABLE 6.266)
Affinity DataIC50:  312nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543684(US11279703, TABLE 6.273)
Affinity DataIC50:  320nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543639(US11279703, TABLE 6.228)
Affinity DataIC50:  322nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543758(US11279703, TABLE 6.348)
Affinity DataIC50:  329nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543649(US11279703, TABLE 6.238)
Affinity DataIC50:  363nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543505(US11279703, TABLE 5.3 | US11279703, TABLE 6.240 | ...)
Affinity DataIC50:  406nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550486(US11306105, Compound 102)
Affinity DataIC50:  458nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550489(US11306105, Compound 105)
Affinity DataIC50:  565nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550501(US11306105, Compound 205)
Affinity DataIC50:  612nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543617(US11279703, TABLE 6.206 | US11279703, TABLE 6.229)
Affinity DataIC50:  632nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM543578(US11279703, TABLE 6.167 | US11279703, TABLE 6.172)
Affinity DataIC50:  638nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM550502(US11306105, Compound 206)
Affinity DataIC50:  642nMAssay Description:Acetyl-Histone Binding Assay. Assays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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