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Adenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.300nMAssay Description:Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.300nMAssay Description:Inhibition of [3H]CHA (N6-cyclohexyl adenosine) to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.300nMAssay Description:Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.320nMMore data for this Ligand-Target Pair

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Adenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.320nMAssay Description:Inhibition of N6-[3H]cyclohexyladenosine binding to guinea pig forebrain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.320nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.400nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in bovine cortical membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.450nMAssay Description:Displacement of [3H]R-PIA or [3H]CGS 21680 from human adenosine A1 receptor in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.450nMAssay Description:Inhibition of [3H]- (R)-P1A binding to adenosine A1 receptorMore data for this Ligand-Target Pair

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Adenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.530nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in pig cortical membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Binding affinity at adenosine A1 receptor from rat brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Binding affinity against Adenosine A1 receptor using [3H]CHA in rat brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Displacement of [3H]CHA from adenosine A1 receptor of rat whole brainMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligandMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Binding affinity towards adenosine A1 receptor on rat whole brain membrane using [3H]N6-cyclohexyladenosineMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Binding affinity against Adenosine A1 receptor using N6-[3H]cyclohexyladenosine in rat brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.590nMAssay Description:Inhibition of binding of [3H]N6-cyclohexyladenosine to adenosine A1 receptor of rat whole brain membranes.Checked by AuthorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.600nMAssay Description:Affinity for Adenosine A1 receptor determined by [3H]N6-cyclohexyladenosine binding to rat brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.760nMAssay Description:Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.800nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.800nMAssay Description:Displacement of [3H]PIA from adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.800nMAssay Description:Binding affinity against low affinity component of adenosine A1 receptors from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 0.800nMMore data for this Ligand-Target Pair

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PDB KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Oryctolagus cuniculus (Rabbit))
Pfizer

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1nMMore data for this Ligand-Target Pair

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Details PubMed

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.10nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair

PDB Reactome pathway
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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.20nMAssay Description:Tested for inhibition of adenosine A1 receptor binding to rat brainMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.20nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor of Wistar rat forebrainMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.20nMAssay Description:Binding affinity against adenosine A1 receptor in rat brain membranes using [3H]CHA as radioligandMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.5nMAssay Description:Displacement of [3H]R-PIA from rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.80nMAssay Description:Displacement of [3H]R-PIA from human A1 adenosine receptor expressed in CHO cells after 60 min by Perkin Elmer Liquid Scintillation AnalyzerMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.25nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.30nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.30nM ΔG°: -45.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assay using adenosine receptor.More data for this Ligand-Target Pair

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Details US Patent

Adenosine receptor A3(Chick)
University Of Illinois At Chicago

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.63nMMore data for this Ligand-Target Pair

Reactome pathway
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PDB Reactome pathway KEGG
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Adenosine receptor A1(Chick)
University Of Illinois At Chicago

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.87nMMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 4.40nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in absence of GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.07nMAssay Description:Binding affinity for adenosine A1 receptor was assayed by displacement of [3H]DPCPX from rat cortical membranes.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.10nMAssay Description:Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR by scintillation counting analysisMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]DPCPX in rat cortical membranes in the absence of GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in rat brain cortical membranes in absence of GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Binding affinity for Adenosine A1 receptor of rat cortical membrane by displacing [3H]DPCPX More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Binding affinity to adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Displacement of [3H]DPCPX from rat cortical membranes Adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]DPCPX in rat cortical membranes in the absence of GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 5.90nMAssay Description:Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 7.14nMAssay Description:Affinity towards adenosine A1 receptor from rat cortical membranes using [3H]DPCPXMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 7.90nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in rat whole brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 7.90nMAssay Description:Displacement of [3H]PD116948 from Long-Evans rat whole brain membrane A1AR incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 8.5nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in Sprague-Dawley rat whole brain after 1 hr by scintillation countingMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 9nM ΔG°: -45.5kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [3H]DPCPX binding from the A1AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined in parallel ass...More data for this Ligand-Target Pair

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Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 10nMAssay Description:Displacement of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 10nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 10nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 10nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in Sprague-Dawley rat whole brain membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 15nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 15nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranes in absence of GTPMore data for this Ligand-Target Pair

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Adenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 20nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]CPX in guinea pig DDT membrane; 19.5+/-12.0More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 21.5nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor in DDT1MF-2 cellsMore data for this Ligand-Target Pair

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Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 26nMAssay Description:Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranesMore data for this Ligand-Target Pair

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Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 26nMAssay Description:Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 35nMAssay Description:Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligandMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 35nMAssay Description:Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligandMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 35nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]DPCPX in rat cortical membranes in the presence of GTP.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 35nMAssay Description:Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 35nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in rat brain cortical membranes in presence of GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 43nMMore data for this Ligand-Target Pair

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PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 43nMAssay Description:Agonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as activation of adenylyl cyclase activityMore data for this Ligand-Target Pair

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UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Oryctolagus cuniculus (rabbit))
Pfizer

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 49nMMore data for this Ligand-Target Pair

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Details PubMed

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 63nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in presence of 0.1 mM GTPMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 72nMAssay Description:Inhibitory activity against Beta-glucosidase from E-coliMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 72nMAssay Description:Affinity for human Adenosine A3 receptor expressed in CHO cellMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 72nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from human A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 89.1nMMore data for this Ligand-Target Pair

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Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 97nMAssay Description:Binding affinity to rat adenosine A3 receptor in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 99nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranes in presence of 0.1 mM GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 120nMAssay Description:Binding affinity for Adenosine A3 receptor expressed in HEK 293 cells by displacing i[125I]-ABMECAMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 120nMAssay Description:Binding affinity athuman Adenosine A3 receptor expressed in HEK 293 cells by [125I]AB-MECA displacement.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 130nMAssay Description:Binding affinity against low affinity component of adenosine A1 receptors from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 130nMAssay Description:Binding affinity against low affinity component of adenosine A1 receptors from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 137nMAssay Description:Binding affinity towards Adenosine A3 receptor (W243 A mutant receptor)More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 142nMAssay Description:Binding affinity towards human Adenosine A3 receptor wild typeMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 230nMAssay Description:Binding affinity towards rat Adenosine A1 receptor using [3H]-DPCPXMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 240nMAssay Description:Binding affinity to human adenosine A3 receptor in CHO cellsMore data for this Ligand-Target Pair

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Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 240nMAssay Description:Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO ...More data for this Ligand-Target Pair

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Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 260nMAssay Description:Affinity to Adenosine A3 receptor of rat testis membrane using [3H](R)-PIA with 150 nM DPCPXMore data for this Ligand-Target Pair

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Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Rattus norvegicus)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 274nMAssay Description:Displacement of [125I]- AB-MECA from rat adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 280nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 281nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 281nMAssay Description:Displacement of [125I]-AB-MECA binding to human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 281nMAssay Description:Affinity towards Adenosine A3 receptor expressed in HEK 293 cells using [125I]AB-MECA radioligandMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
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Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 321nMAssay Description:Tested for inhibition of adenosine A2 receptor binding to rat brainMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 321nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2A receptor of rat striatal tissueMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 331nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Sprague-Dawley rat striatal membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 336nMAssay Description:Binding affinity against adenosine A2 receptor from rat striatum using [3H]NECA as radioligand.More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 336nMAssay Description:Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 380nMAssay Description:Affinity to Adenosine A2A receptor of rat brain striatum using [3H]-CGS- 21680More data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 385nMAssay Description:Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.More data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 390nMAssay Description:Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway
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GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 421nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatal membranes using [3H]NECA as radioligandMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 460nMAssay Description:Displacement of [3H]NECA from rat striatal A2A adenosine receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 460nMAssay Description:Binding affinity at adenosine A2 receptor from rat striatal membranes by [3H]NECA displacement.More data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 460nMAssay Description:Binding affinity towards adenosine A2 receptor on rat striatal membrane using [3H]NECA as radioligandMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 460nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Binding affinity for Adenosine A1 receptor in corpora striata of rats using [3H]NECAMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Binding affinity against Adenosine A2 receptor using [3H]NECA with 50 nM CPA in rat striatal brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Affinity for Adenosine A2 receptor determined by [3H]NECA binding to rat striatal membranesMore data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Displacement of [3H]R-PIA or [3H]CGS 21680 from human adenosine A2A receptor in CHO cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 462nMAssay Description:Binding affinity for Adenosine A1 receptor in corpora striata of rats using [3H]NECAMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 510nMMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 510nMAssay Description:Inhibition of [3H]- NECA binding to adenosine receptor A2More data for this Ligand-Target Pair

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Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A3(Mus musculus)
Medical College Of Wisconsin

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 534nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from mouse A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 557nMAssay Description:Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysisMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 580nMAssay Description:Binding affinity against Adenosine A2A receptor using [3H]-CGS- 21680 as the radioligand in rat striatal membranesMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 580nMAssay Description:Binding affinity against Adenosine A2A receptor using [3H]-CGS- 21680 as the radioligand in rat striatal membranesMore data for this Ligand-Target Pair

Purchase CHEMBL MMDB PC cid PC sid PDB Patents Similars

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 580nMAssay Description:Binding affinity against Adenosine A2A receptor by using [3H]CGS-21680 as radioligandMore data for this Ligand-Target Pair

Purchase CHEMBL MMDB PC cid PC sid PDB Patents Similars

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 580nMAssay Description:Binding affinity for adenosine A2A receptor of rat striatal membrane by displacing [3H]-ZM 241385More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 580nMAssay Description:Displacement of [3H]-CGS- 21980 from Adenosine A2A receptor of rat striatal membranes More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 615nMAssay Description:Binding affinity towards Adenosine A3 receptor (H95A mutant receptor)More data for this Ligand-Target Pair

Purchase CHEMBL MMDB PC cid PC sid PDB Patents Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 790nMAssay Description:Displacement of [3H]-ZM 241385 binding to human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

Purchase CHEMBL MMDB PC cid PC sid PDB Patents Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 794nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 794nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from human A2A adenosine receptor expressed in HEK293 cell m...More data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 794nMMore data for this Ligand-Target Pair

Purchase CHEMBL MMDB PC cid PC sid PDB Patents Similars

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 794nMAssay Description:Displacement of [3H]CGS21680 from human A2a adenosine receptor expressed in HEK293 cells after 60 min by Perkin Elmer Liquid Scintillation AnalyzerMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Mus musculus)
Medical College Of Wisconsin

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 808nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from mouse A2A adenosine receptor expressed in HEK293 cell m...More data for this Ligand-Target Pair

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Adenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 810nMAssay Description:Displacement of [3H]CGS21680 from adenosine A1 receptor in pig striatum membraneMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 857nMAssay Description:Displacement of specific [3H]-CGS- 21680 binding to adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Equilibrative nucleoside transporter 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.10E+3nMAssay Description:Inhibition of [3H]NBTI binding to equilibrative nucleoside transport protein 1 (ENT1) in human erythrocyte membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.22E+3nMAssay Description:Displacement of [3H]CGS21680 from adenosine A1 receptor in bovine striatum membraneMore data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.65E+3nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Adenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.70E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.00E+3nMAssay Description:Binding affinity against adenosine A1 receptors from rat brain membranes using [3H]CCPAMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.00E+3nMMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.00E+3nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Adenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.40E+3nMAssay Description:Binding affinity against high affinity component of adenosine A1 receptors from rat brain membranes using [3H]DPCPXMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.47E+3nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 3.25E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Adenosine receptor A2a(Rattus norvegicus (rat))
Novo Nordisk

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 3.37E+3nMAssay Description:Binding affinity for adenosine A2A receptor was determined by displacement of [3H]-DPCPX from rat striatal membranes.More data for this Ligand-Target Pair

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PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Details PubMed

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 1.86E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

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PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.12E+4nMAssay Description:Displacement of [3H]- ZM-241385 from human adenosine A2B receptor expressed in HEK cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

Ki: 2.95E+4nMAssay Description:Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR in presence of GTP by radioligand binding assayMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 0.320nMAssay Description:Evaluated for binding affinity against Adenosine A1 receptorChecked by AuthorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 0.350nMAssay Description:Binding affinity to adenosine A1 receptor of rat brain membranes without NaCl by inhibition of [125-I]-labeled aminobenzyl adenosine bindingMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 1nMAssay Description:Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 2.70nMAssay Description:Agonist activity at adenosine A1 receptor assessed as inhibition of isoproterenol-stimulated cAMP accumulation in DDT1MF-2 cellsMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 7.10nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortical membrane in absence of 100 uM GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 8.30nMAssay Description:Displacement of [3H]DPCPX from rat brain cortical membrane A1AR assessed as GTP shiftMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 58nMAssay Description:Inhibition of Adenylate cyclase activity in rat fat cell membrane at adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 65nMAssay Description:Displacement of [3H]DPCPX from rat brain cortical membrane A1AR in absence of GTP by scintillation counting analysisMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 154nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortical membrane in presence of 100 uM GTPMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 538nMAssay Description:Displacement of [3H]DPCPX from rat brain cortical membrane A1AR in presence of 100 uM of GTP by scintillation counting analysisMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 640nMAssay Description:Evaluated for the binding affinity towards the Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 720nMAssay Description:Binding affinity towards adenosine A1 receptor rat brain membranes with 1 M NaCl by inhibition of [125-I]-labeled aminobenzyl adenosine bindingMore data for this Ligand-Target Pair

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PDB Reactome pathway
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Adenosine receptor A2a/A2b(Rattus norvegicus)
Merrell Dow Research Institute

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 1.16E+3nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 1.10E+4nMAssay Description:Inhibition of photolabeling of 34 kDa polypeptide in adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 1.40E+4nMAssay Description:Inhibition of photolabeling of 24 kDa polypeptide in adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Genome polyprotein(West Nile virus)
University Of Pittsburgh

Curated by PubChem BioAssay

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: >5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair

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Details PCBioAssay

23S rRNA methylase leader peptide(Escherichia coli)TBA

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 6.30E+4nMMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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rRNA adenine N-6-methyltransferase(Bacillus subtilis)TBA

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 8.00E+4nMMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Phosphoglycerate kinase 1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: 3.90E+6nMAssay Description:evaluated for the inhibition of Trypanosoma brucei Phosphoglycerate kinase (PGK)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

Glyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

IC50: >5.00E+6nMAssay Description:Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicanaMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 7.98E+3nMAssay Description:Stimulation of [35S]GTP-gamma-S, against human adenosine A3 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 4.20nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to human adenosine A1 receptorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
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Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 20nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to adenosine A1 receptor of rat cerebral cortical membraneMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

Adenosine receptor A2a/A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 2.20E+3nMAssay Description:Stimulation of adenylate cyclase activity in human platelet membrane at A2 receptorMore data for this Ligand-Target Pair

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Adenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 12.6nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 0.190nMAssay Description:Compound was evaluated for the Adenosine A1 receptor agonist potency.More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 16.9nMAssay Description:Agonist activity at adenosine A1 receptor in rat cortical membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 14nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Adenosine receptor A1(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 13.3nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to rat brain membranes by adenosine A1 receptor activationMore data for this Ligand-Target Pair

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Adenosine receptor A1(GUINEA PIG)
Kyowa Hakko Kogyo

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 7.90nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 6.30nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 10 mins by l...More data for this Ligand-Target Pair

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PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Adenosine receptor A3(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP K_i Database

BDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)

EC50: 242nMAssay Description:Effect on forskolin-stimulated cyclic AMP production in intact chinese hamster ovary (CHO) cell expressing the human Adenosine A3 receptorMore data for this Ligand-Target Pair

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