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Found 2 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 1 [601-1600]'
TargetDNA (cytosine-5)-methyltransferase 1 [601-1600](Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491448(US10975056, Example 422 | US11771711, Reference co...)
Affinity DataIC50:  79nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Human truncated DNMT1(601-1600),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA (cytosine-5)-methyltransferase 1 [601-1600](Homo sapiens (Human))
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491184(2-(4-Chlorophenyl)-2-((3,5-dicyano-6-(dimethylamin...)
Affinity DataIC50:  631nMAssay Description:This assay used Scintillation Proximity technology in a signal increase format to evaluate the potency of compounds. Human truncated DNMT1(601-1600),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent