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Found 5 Enz. Inhib. hit(s) with Target = 'T-type calcium channel alpha 1G subunit'
TargetT-type calcium channel alpha 1G subunit(Mus musculus)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50452245(Act-709478)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of Cav3.1 in mouse assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT-type calcium channel alpha 1G subunit(Mus musculus)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50514577(CHEMBL3581591)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetT-type calcium channel alpha 1G subunit(Mus musculus)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50514578(CHEMBL4464354)
Affinity DataIC50:  2.30E+3nMAssay Description:Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetT-type calcium channel alpha 1G subunit(Mus musculus)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090184(CHEMBL3581573)
Affinity DataIC50:  3.50E+3nMAssay Description:Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT-type calcium channel alpha 1G subunit(Mus musculus)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50514579(CHEMBL4575063)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as increase in current amplitude at holding potential of -100 mV by whole cell e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed