- peroxisome proliferator-activated receptor gamma (ppar gamma)
- gamma secretase
- gamma-cystathionase
- gamma-secretase
- ppar-gamma
- rar-gamma
- gamma-aminobutyric acid receptor subunit alpha-1/gamma-2
- dag kinase gamma
- g gamma-i
- gamma hydroxybutyric, ghb
- gamma-carbonic anhydrase
- gamma-glutamylcysteine synthetase
- gmp-pde gamma
- p38 delta/gamma
- ppar alpha/gamma
- gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2
- gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-1
- gamma-aminobutyric acid receptor subunit alpha-2/beta-3/gamma-2
- gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2
- gamma-aminobutyric acid receptor subunit alpha-4/beta-2/gamma-2
- gamma-aminobutyric acid receptor subunit alpha-4/beta-3/gamma-2
- gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-1
- gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2
- gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2
- akap-7 isoform gamma
- dna-pk/ p110-gamma
- interferon gamma receptor 1
- interferon gamma-inducing factor
- nuclear receptor ror-gamma
- phospholipase c, gamma 1
- phospholipase c-gamma-1
- phospholipase c-gamma-2
- pi3k-alpha/ p110-gamma
- retinoic acid receptor gamma
- retinoic acid receptor, gamma
- gamma-secretase subunit aph-1a/gamma-secretase subunit aph-1b/gamma-secretase subunit pen-2/nicastrin/presenilin-1/presenilin-2
- 14-3-3 protein gamma
- cam kinase ii delta/gamma
- casein kinase i gamma 2
- gaba receptor gamma-1 subunit
- gamma carbonic anhydrase family protein
- gamma-amino-n-butyrate transaminase
- gamma-secretase subunit pen-2
- nuclear receptor ror-gamma (rorc)
- peroxisome proliferator-activated receptor gamma
- phosphoinositide 3-kinase (pi3k), gamma
- phosphoinositide 3-kinase-c2-gamma
- protein-glutamine gamma-glutamyltransferase 2
- protein-glutamine gamma-glutamyltransferase 6
- protein-glutamine gamma-glutamyltransferase e
- protein-glutamine gamma-glutamyltransferase k
- protein-glutamine gamma-glutamyltransferase z
- protein-glutamine gamma-glutamyltransferase, liver
- retinoic acid receptor rxr-gamma
- retinoic acid receptors gamma / alpha
- retinoid-related orphan receptor-gamma
- urease subunit alpha/beta/gamma
- gamma-secretase subunit aph-1a/gamma-secretase subunit pen-2/nicastrin [34-709]/presenilin-1
- acetylcholine receptor; alpha1/beta1/delta/gamma
- casein kinase i gamma 1 isoform
- nuclear receptor ror-gamma [238-497]
- nuclear receptor ror-gamma [258-518]
- peroxisome proliferator-activated receptor gamma (pparg)
- receptor-type tyrosine-protein phosphatase gamma
- retinoic acid receptor gamma [183-417]
- retinoic acid receptor rxr-alpha/gamma
- retinoid-related orphan receptor-gamma (rorgt)
- serine/threonine-protein kinase mrck gamma
- urease subunit alpha [f36l]/beta/gamma
- gamma-aminobutyric acid receptor subunit alpha-1 [g200c]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-1 [s205c]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-1 [t206c]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-1 [v202c]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-1 [v211c]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-3 [26-473]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-3 [26-473]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-3 [26-473]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-2 [26-512]/gamma-2 [40-467]
- gamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-3 [26-473]/gamma-2 [40-467]
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1
- acetylcholine receptor subunit alpha/beta/delta/gamma
- amp-activated protein kinase, gamma-1 subunit
- camp-dependent protein kinase catalytic subunit gamma
- eukaryotic translation initiation factor 4 gamma 1
- gamma-aminobutyric acid receptor subunit alpha (gabaa)
- gamma-aminobutyric acid receptor subunit alpha-1
- gamma-aminobutyric acid receptor subunit alpha-3
- gamma-aminobutyric acid receptor subunit beta-1
- gamma-aminobutyric acid receptor subunit rho-1
- gamma-aminobutyric acid receptor subunit rho-2
- gamma-aminobutyric acid receptor subunit rho-3
- mitogen-activated protein kinase 12 (p38 gamma)
- nicotinic acetylcholine receptor alpha1/beta1/gamma/delta
- nuclear receptor ror-gamma (aa 262-507)
- nuclear receptor ror-gamma [258-518,y502f]
- peroxisome proliferator-activated receptor alpha/delta/gamma
- peroxisome proliferator-activated receptor gamma [205-505]
- voltage-dependent calcium channel gamma-1 subunit
- gamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,a118c]
- gamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,m169c]
- gamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,t120c]
- acetylcholine receptor protein alpha/beta/delta/gamma chain
- gabaa receptor, alpha-3, beta-2, gamma-2
- gabaa receptor, alpha-4, beta-3, gamma-2
- gabaa receptor, alpha-5, beta-2, gamma-2
- gabaa receptor, alpha-5, beta-3, gamma-2
- gabaa subunit alpha-1, beta-2, gamma-2
- gamma-aminobutyric acid receptor subunit alpha-2 (gabra2)
- gamma-aminobutyric acid receptor subunit alpha-2/delta
- phosphatidylinositol 3-kinase c2 domain-containing subunit gamma
- phosphatidylinositol 4-phosphate 5-kinase type i gamma
- phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- pi(5)p 4-kinase type ii gamma
- retinoic acid-related nuclear receptor gamma t (rorgammat)
- retinoid x receptor gamma/retinoic acid receptor alpha
- serine/threonine-protein phosphatase pp1-gamma catalytic subunit
- gamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-200],p14867[176-456]
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [663-759]
- ampk complex 1 (alpha-1,beta-1,gamma-1)
- ampk complex 7 (alpha-2,beta-1,gamma-1)
- gaba a receptor alpha-1/beta-1/gamma-2
- gaba a receptor alpha-2/beta-2/gamma-2
- gaba a receptor alpha-3/beta-2/gamma-2
- gaba a receptor alpha-4/beta-3/gamma-2
- gaba a receptor alpha-5/beta-3/gamma-2
- gaba a receptor alpha-6/beta-2/gamma-2
- gaba receptor alpha-1/beta-1/gamma-2 subunit
- gaba receptor alpha-1/beta-2/gamma-2 subunit
- gaba receptor alpha-2/beta-2/gamma-2 subunit
- gaba receptor alpha-2/beta-3/gamma-2 subunit
- gaba receptor alpha-3/beta-3/gamma-2 subunit
- gaba receptor alpha-4/beta-3/gamma-2 subunit
- gaba receptor alpha-5/beta-3/gamma-2 subunit
- gaba receptor alpha-6/beta-2/gamma-2 subunit
- gaba-a receptor; alpha-1/beta-3/gamma-2
- gaba-a receptor; alpha-5/beta-3/gamma-2
- gaba-a receptor; alpha-6/beta-3/gamma-2
- gamma-aminobutyric acid receptor (gaba(a)) subunit alpha-4
- gamma-aminobutyric acid receptor subunit alpha-1/beta-1
- gamma-aminobutyric acid receptor subunit alpha-1/beta-2
- gamma-aminobutyric acid receptor subunit alpha-1/beta-3
- gamma-aminobutyric acid receptor subunit alpha-4/beta-3
- gamma-aminobutyric acid receptor subunit alpha-4/beta3/delta
- gamma-aminobutyric acid receptor subunit alpha-6/beta-2
- gamma-aminobutyric acid receptor subunit alpha-6/beta-3
- gamma-aminobutyric acid receptor subunit beta-1/beta-2
- gamma-aminobutyric acid type b receptor subunit 1/2
- peroxisome proliferator-activated receptor gamma/nuclear receptor corepressor 2
- phosphatidylinositol 4,5-biphosphate 3-kinase catalytic subunit gamma (pik3cg)
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- phosphorylase b kinase gamma catalytic chain, liver/testis isoform
- protein-glutamine gamma-glutamyltransferase 2/tyrosine-protein kinase jak3
- retinoic acid-related nuclear receptor gamma t (ror t)
- serine/threonine-protein phosphatase 2b catalytic subunit gamma isoform
- amp-activated protein kinase alpha-2/beta-2/gamma-2
- calcium/calmodulin-dependent protein kinase type ii subunit gamma (camkllg)
- gabaa receptor mutant, alpha-1 (a160c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1 (d97c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1 (f99c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1 (g157c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1 (s204c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1 (t162c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1 (y209c), beta-2, gamma-2
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (d56c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (f77c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (l140c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (r132c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (r144c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (r185c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (r194c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (t126c)
- gabaa receptor mutant, alpha-1, beta-2, gamma-2 (t142c)
- gamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta
- gamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta
- gamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta
- gamma-aminobutyric acid receptor subunit alpha-4/beta-2/delta
- gamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta
- gamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta
- gamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta
- peroxisome proliferator-activated receptor gamma/retinoic acid receptor rxr-alpha
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/gamma isoform
- phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (144-1102)
- protein-glutamine gamma-glutamyltransferase 2/receptor-type tyrosine-protein phosphatase eta
- calcium/calmodulin-dependent protein kinase type ii subunit alpha/beta/delta/gamma
- peroxisome proliferator-activated receptor gamma [182-505]/regulatory protein gal4 [1-147]
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta/gamma isoform
- protein kinase c alpha/beta/delta/epsilon/eta/gamma/theta/zeta type
Guanosine 5 -(gamma-S)triphosphate BDBM35866 GTP-gamma-S gamma-Thio-GTP
3-(gamma,gamma-dimethylallyl)resveratrol BDBM50269596 CHEMBL457145
BDBM50269598 3-(gamma,gamma-dimethylpropenyl)moracinM CHEMBL463125
BDBM50269599 5-(gamma,gamma-dimethylallyl)-oxyresveratrol CHEMBL463126
gamma-cyclodextrin BDBM36126
alpha-methyl-gamma,gamma-diphenylallenecarboxylic acid ethyl ester CHEMBL443611 BDBM50292631
CHEMBL558092 BDBM50294101 N1-Benzylamine-N3-(gamma,gamma-dimethylallyl)guanidine Bis-(trifluoroacetate)
TMe-gamma-cyclodextrin BDBM36248
gamma-methyl-APB BDBM82005
4-[N3-gamma,gamma-Dimethyallyl)guanidino]-1-guanidino-butane bis(trifluoroacetate) BDBM50294103 CHEMBL549342
BDBM50205417 CHEMBL220200 UTP-gamma-S
BDBM50250088 [gamma-lactam4,5]PACAP27 CHEMBL524528
BDBM50250089 CHEMBL501268 [gamma-lactam4,5]PACAP38
CHEMBL514745 3'-[gamma-hydroxymethyl-(E)-gamma-methylallyl]-2,4,2',4'-tetrahydroxychalcone 11'-O-coumarate BDBM50250979
N1-[3'-Aminopropyl)-3-aminopropyl]-N3-(gamma,gamma-dimethylallyl)-guanidine bis(trifluoroacetate) CHEMBL553638 BDBM50294102
Cycloartenol Trans-Ferulate BDBM50483936 Gamma Oryzanol 3-O-Ferulylcycloartenol Cycloartenyl Ferulate Cycloartenol Ferulate Gamma-Oryzanol
KWELL Gammallin Gexane BDBM50410525 LINDANE HEXICIDE Gamma Benzene Hydrochloride Gammaxene GAMENE HEXACHLORANE BENZENE HEXACHLORIDE, GAMMA
BDBM50275048 CHEMBL446976 2-octyl gamma-bromoacetoacetate
BDBM92992 L-glutamate gamma-methyl ester
CHEMBL1098291 BDBM50531188 Carnosic Acid Gamma-Lactone
CHEMBL244883 BDBM50199731 methotrexate gamma-hydroxamic acid
CHEMBL85937 BDBM50104419 Glutamyl-gamma-boronate analogue
CHEMBL87796 Glutamyl-gamma-boronate analogue BDBM50104413
NSC_440317 BDBM86479 CAS_440317 ATP,Gamma S
alpha, gamma-diketo acid, 1 BDBM33409
(2S)-6-(gamma,gamma-dimethylallyl)-3',4'-dimethoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone BDBM50241693 CHEMBL516860
CHEMBL267603 BDBM50199734 folate gamma-L-phenylalaninehydroxamic acid
US9328123, Rotenone B BDBM224807 Gamma-irradiated rotenone
methotrexate gamma-L-phenylalaninehydroxamic acid CHEMBL396296 BDBM50199733
CHEMBL464609 BDBM50241692 (2S)-6-(gamma,gamma-dimethylallyl)-5,4'-dihydroxy-3'-methoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone
4-Hydroxyvaleric acid lactone dihydro-5-methyl-2(3H)-furanone gamma-valerolactone 4-Valerolactone gamma-Pentanolactone 4-Methyl-4-hydroxybutanoic acid lactone CHEMBL195593 5-methyldihydrofuran-2(3H)-one BDBM50168010 4-Pentanolide gamma-Pentalactone 4-Methyl-gamma-butyrolactone 4-Hydroxypentanoic acid lactone
(2S)-6-(gamma,gamma-dimethylallyl)-5-3'-dihydroxy-4'-methoxy-6'',6''dimethylpyran[2'',3''7,8]flavanone CHEMBL451703 BDBM50241688
CHEMBL455606 BDBM50241687 (2S)-6-(gamma,gamma-dimethylallyl)-5-hydroxy-3',4'-dimethoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone
CHEMBL494570 1-(6-aminohexyl)-3-(3-methylbut-2-enyl)guanidine BDBM50294113 N-(gamma,gamma-Dimethylallyl)-N-(6-aminohexyl)-guanidine
N-(gamma,gamma-Dimethylallyl)-N-(5-aminopentyl)-guanidine BDBM50294112 1-(5-aminopentyl)-3-(3-methylbut-2-enyl)guanidine CHEMBL495424
CHEMBL1398 Alpha-Phenyl-Gamma-Butyrolactone alpha-phenylbutyrolactone BDBM50180937
CHEMBL388879 methotrexate gamma-L-proline-hydroxamic acid BDBM50199735
Gamma2-MSH GAMMA-MSH BDBM82413 CAS_72711-43-4
GHB BDBM50023575 4-hydroxybutanoic acid 4-hydroxybutyric acid 4-hydroxy-butyric acid CHEMBL1342 Xyrem gamma-hydroxybutyric acid Gamma Hydroxybutyric Acid
4,4-difluoro-N(gamma)-hydroxy-L-arginine CHEMBL476417 BDBM50266728
2-Nitrooxy-N-[3-(1,2,3,4-tetrahydro-acridin-9-ylamino)-propyl]-acetamide 9-[N-gamma-(2'-(nitrooxy)acetyl)-gamma-aminopropylamino]-1,2,3,4-tetrahydroacridine CHEMBL269865 BDBM50233367
BDBM50270551 P1,P4-di(uridine 5'-)beta,gamma-difluoromethylenetetraphosphate CHEMBL502712
CAS_57659-38-8 Acetylenic GABA-7 BDBM81477 GAMMA-ACETYLENIC GABA
P1,P4-di(uridine 5'-)beta,gamma-dichloromethlyenetetraphosphate BDBM50270552 CHEMBL476021
adenosine 5'-O-(3-thiotriphosphate) ATP{gamma}S BDBM36312
9-[N-gamma-(3'-(nitrooxy)propyl)-gamma-aminobutylamino]-1,2,3,4-tetrahydroacridine BDBM50233374 N-(3-Nitrooxy-propyl)-N'-(1,2,3,4-tetrahydro-acridin-9-yl)-butane-1,4-diamine CHEMBL407320
2,8-dimethyl-5-(2-pyrazine-2-ylethyl)-gamma-carboline CHEMBL1783970 BDBM50346049
1-(Guanidino)-17-(N1-(gamma,gamma-dimethylallyl)guanidino)-9-azaheptadecane tris(trifluoroacetate) BDBM50294104 CHEMBL560699 N-(8-{8-[N'-(3-Methyl-but-2-enyl)-guanidino]-octylamino}-octyl)-guanidine
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- ChEMBL_1753388 (CHEMBL4188148) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production pre-incubated for 1 hr followed by IFN-gamma addition and measured after 18 hrs
- ChEMBL_1737497 (CHEMBL4153247) Antagonist activity at P2X7 in LPS/IFN gamma differentiated human THP-1 cells
- ChEMBL_2078875 (CHEMBL4734666) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells centrifuged for 10 mins
- ChEMBL_1650863 (CHEMBL3999997) Inhibition of IDO1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine levels preincubated for 15 mins followed by IFN-gamma/LPS stimulation for overnight by LC/MS/MS analysis
- ChEMBL_1838987 (CHEMBL4339120) Inhibition IDO1 in LPS/IFN-gamma stimulated human whole blood assessed as reduction in tryptophan/kynurenine level preincubated for 15 mins followed by LPS/IFN-gamma stimulation measured after 20 hrs by LC-MS/MS analysis
- ChEMBL_1670928 (CHEMBL4020957) Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs followed by IFN-gamma addition measured after 1 hr by In-cell western assay
- ChEMBL_2526317 Inhibition of JAK1/JAK2 in human whole blood assessed as reduction in IFN-gamma-induced STAT1 phosphorylation in monocytes preincubated for 1 hr followed by IFN-gamma stimulation and measured after 8 to 20 mins by FACS analysis
- ChEMBL_853436 (CHEMBL2155294) Inhibition of COX2-mediated 2-arachidonoylglycerol oxygenation in LPS/IFN-gamma-stimulated mouse RAW264.7 cells assessed as 2-AG to PGE2-G/PGD2-G conversion treated 2 hrs after LPS/IFN-gamma stimulation measured after 6 hrs
- ChEMBL_2545854 Inhibition of JAK1/JAK2 signaling pathway in human U2OS cells assessed as reduction in IFN-gamma-induced STAT1 phosphorylation preincubated with compound for 1 hr followed by IFN-gamma addition and measured after 1 hr by TR-FRET analysis
- ChEMBL_2107563 (CHEMBL4816238) Inhibition of IFN-gamma-induced STAT1 transcriptional activity in human HepG2 cells by luciferase reporter gene assay
- ChEMBL_2119554 (CHEMBL4828620) Inhibition of IDO1 in IFN-gamma induced human HeLa cells measured after 48 hrs by fluorescence assay
- ChEMBL_2316503 Inhibition of IDO1 in IFN-gamma treated human HeLa cells incubated for 48 hrs by absorbance based analysis
- ChEMBL_1909137 (CHEMBL4411583) Inhibition of JAK1/JAK2 signaling pathway in human CD14 +ve cells of whole blood assessed as reduction in IFN-gamma induced STAT1 phosphorylation preincubated for 45 mins followed by IFN-gamma addition and measured measured after 15 mins by FACS assay
- ChEMBL_1685554 (CHEMBL4036033) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate after 24 hrs
- ChEMBL_1779693 (CHEMBL4236685) Inhibition of IFN-gamma-stimulated IDO1 in human HeLa cells after 24 hrs by Ehrlich's reagent based assay
- ChEMBL_590887 (CHEMBL1042997) Inhibition of indoleamine 2,3-dioxygenase in IFN-gamma-stimulated human HeLa cells assessed as kynurenine formation by spectrophotometry
- ChEMBL_652247 (CHEMBL1225450) Inhibition of indoleamine-2,3-dioxygenase in human A431 cells assessed as inhibition of IFN-gamma-stimulated kynurenine production
- ChEMBL_1650851 (CHEMBL3999985) Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
- ChEMBL_1784807 (CHEMBL4256324) Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
- ChEMBL_1913238 (CHEMBL4415821) Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
- ChEMBL_2124799 (CHEMBL4834032) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells incubated for 48 hrs by fluorescence microplate reader assay
- ChEMBL_2022039 (CHEMBL4675852) Inhibition of JAK1/JAK2 signaling pathway in human whole blood spiked with CD14 +ve cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation preincubated for 45 mins followed by IFN-gamma addition and measured measured after 15 mins immunostaining based by FACS assay
- ChEMBL_2035528 (CHEMBL4689686) Inhibition of IDO1 in LPS and IFN-gamma-stimulated human Whole blood assessed as reduction in kynurenine production using isotope-labeled tryptophan as substrate incubated for 15 mins followed by LPS and IFN-gamma stimulation measured after 18 hrs by LC-MS/MS analysis
- ChEMBL_1855397 (CHEMBL4356126) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production incubated for 18 hrs
- ChEMBL_1869802 (CHEMBL4370868) Inhibition of IDO1 in IFN-gamma-induced human HeLa cells assessed as reduction in L-kynurenine level after 24 hrs
- ChEMBL_2069926 (CHEMBL4725179) Inhibition of IDO1 in recombinant IFN-gamma induced human HeLa cells incubated for 18 hrs by fluorescence microplate reader assay
- ChEMBL_2069927 (CHEMBL4725180) Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay
- ChEMBL_2078890 (CHEMBL4734681) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells incubated for 6 hrs by p-dimethylaminobenzaldehyde reagent based assay
- ChEMBL_2207937 (CHEMBL5120645) Inhibition of JAK1/JAK2 signaling pathway in human U-937 cells assessed as reduction of IFN-gamma induced ICAM1 expression
- ChEMBL_2246301 (CHEMBL5160511) Inhibition of IDO1 in IFN gamma-stimulated human HeLa cells measured after 48 hrs by fluorescence based microplate reader assay
- ChEMBL_1758066 (CHEMBL4193074) Inhibition of IFN-gamma stimulated STAT3 (unknown origin) expressed in human HeLa cells after 6 hrs by luciferase reporter gene assay
- ChEMBL_1936260 (CHEMBL4482019) Inhibition of IDO1 in IFN-gamma/LPS stimulated human THP-1 cells assessed as reduction in kynurenine production after 24 hrs
- ChEMBL_2078894 (CHEMBL4734685) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells incubated for 48 hrs by p-dimethylaminobenzaldehyde reagent based colorimetric assay
- ChEBML_1703591 Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2 induced IFN-gamma production after 18 hrs by ELISA
- ChEMBL_1546967 (CHEMBL3748070) Inhibition of IFN-gamma-stimulated IDO1 activity in human HeLa cells using L-tryptophan as substrate after 48 hrs by spectrophotometric analysis
- ChEMBL_1576410 (CHEMBL3802839) Inhibition of IFN gamma-induced STAT3 (unknown origin) activation in HeLa-STAT3-Luc cells after 6 hrs by luciferase reporter gene assay
- ChEMBL_1988859 (CHEMBL4622406) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay
- ChEMBL_2078858 (CHEMBL4734649) Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells incubated for 48 hrs using L-tryptophan as substrate by absorbance method
- ChEMBL_1546974 (CHEMBL3748077) Inhibition of IFN-gamma-stimulated IDO1 activity in human HeLa cells using L-tryptophan as substrate after 48 hrs by microplate reader analysis
- ChEMBL_1703591 (CHEMBL4054824) Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2 induced IFN-gamma production after 18 hrs by ELISA
- ChEMBL_1857722 (CHEMBL4358451) Inhibition of IDO1 in IFN-gamma/LPS stimulated human PBMC assessed as reduction in kynurenine production after 48 hrs by RapidFire MS assay
- ChEMBL_1857750 (CHEMBL4358479) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production after 48 hrs by RapidFire MS assay
- ChEMBL_1936259 (CHEMBL4482018) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production incubated for 24 hrs relative to control
- ChEMBL_2224438 (CHEMBL5137951) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells in presence of heme measured after 20 hrs by heme-competitive binding assay
- ChEMBL_2491108 Inhibition of IDO1 in IFN-gamma induced human HeLa cells using L-tryptophan as substrate incubated for 24 hrs by absorbance based microplate analysis
- ChEMBL_2015001 (CHEMBL4668579) Inhibition of LPS/IFN-gamma induced NO-dependent iNOS activity in mouse RAW 264.7 cells incubated for 16 hrs by Griess reagent based assay
- ChEMBL_2069931 (CHEMBL4725184) Inhibition of IDO1 in IFN-gamma/LPS induced human whole blood assessed as tryptophan/kynurenine level measured after 18 hrs by RapidFire mass spectrometry
- ChEMBL_2078869 (CHEMBL4734660) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-Trp as substrate incubated for 48 hrs by Ehrlich reagent based assay
- ChEMBL_2078872 (CHEMBL4734663) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as effect on KYN level incubated for 48 hrs by rapidfire-mass spectrometry
- ChEMBL_1707523 (CHEMBL4058756) Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB method
- ChEMBL_1759370 (CHEMBL4194378) Inhibition of IDO1 in human IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production using L-tryptophan substrate incubated for 24 hrs
- ChEMBL_1907196 (CHEMBL4409554) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 24 hrs
- ChEMBL_2078877 (CHEMBL4734668) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as effect on kynurenine level incubated for 48 hrs by p-dimethylaminobenzaldehyde based assay
- ChEMBL_1707524 (CHEMBL4058757) Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human THP1 cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB method
- ChEMBL_1707525 (CHEMBL4058758) Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine production after 24 hrs by LC-MS/MS method
- ChEMBL_2054791 (CHEMBL4709792) Inhibition of IDO1 in IFN-gamma-induced human HeLa cells assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 24 hrs
- ChEMBL_1923386 (CHEMBL4426342) Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs by infrared scanning analysis
- ChEMBL_2078855 (CHEMBL4734646) Inhibition of IDO1 in human HeLa cells preincubated for 1 hr followed by IFN-gamma stimulation and measured after 20 hrs by Ehrlich colorimetric reagent based assay
- ChEMBL_2184624 (CHEMBL5096706) Agonist activity at mouse STING assessed as IFN-beta secretion
- ChEMBL_1994392 (CHEMBL4628287) Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 24 hrs by UV-spectrophotometry
- ChEMBL_1855446 (CHEMBL4356175) Inhibition of IFN-gamma stimulated IDO1 in human HeLa cells assessed as reduction in formation of kynurenine incubated for 48 hrs in presence of IFNgamma by microplate reader assay
- ChEMBL_2035521 (CHEMBL4689679) Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated for 48 hrs by fluorescence based assay
- ChEMBL_2046340 (CHEMBL4701039) Antagonist activity at adenosine 2A receptor in BALB/c mouse T cells assessed as reduction in CGS-21680-induced suppression of IFN-gamma secretion incubated for 24 hrs by ELISA
- ChEMBL_2162573 (CHEMBL5047434) Inhibition of JAK1/JAK3 signalling in human PBMC assessed as inhibition of IL-2 stimulated IFN-gamma release incubated for 1 hr followed by IL-2 stimulation by MSD assay
- ChEMBL_2285162 Inhibition of IFN-alpha induced STAT3 phosphorylation in human PBMC preincubated with compound for 30 mins followed by IFN-alpha stimulation and measured after 15 mins by flow cytometric analysis
- ChEMBL_1843570 (CHEMBL4343997) Inhibition of STING in human THP1 cells by IFN reporter gene assay
- ChEMBL_1349852 (CHEMBL3268428) Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay
- ChEMBL_1513935 (CHEMBL3611617) Antagonist activity at Kv1.3 in human whole blood assessed as inhibition of thapsigargin-induced IFN-gamma secretion incubated for 30 prior to thapsigargin induction measured after 48 hrs by electrochemilluminescent immunoassay
- ChEMBL_1620337 (CHEMBL3862620) Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma addition measured after 6 hrs by luciferase reporter gene assay
- ChEMBL_2373096 Agonist activity at STING in human THP-1 cells by IFN-reporter based assay
- ChEMBL_2292020 Inhibition of JAK1/TYK2 in human M07E cells assessed as reduction of IFN alpha stimulated STAT phosphorylation preincubated for 30 mins followed by IFN alpha stimulation for 15 mins by flow cytometry method
- ChEMBL_1555055 (CHEMBL3767633) Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning at 100 uM after 24 hrs by microtiter plate reader
- ChEMBL_1555056 (CHEMBL3767634) Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning at 400 uM after 24 hrs by microtiter plate reader
- ChEMBL_161149 (CHEMBL767417) Inhibition of Protein kinase C gamma (PKC-gamma)
- ChEMBL_1350279 (CHEMBL3267262) Binding affinity to IFNAR (unknown origin) assessed as inhibition of interaction with IFN-alpha
- ChEMBL_1368159 (CHEMBL3299207) Inhibition of JAK1/TYK2 in human whole blood assessed as inhibition of IFN-alpha-induced STAT-3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition measured after 15 mins by FACS analysis
- ChEMBL_2309268 Inhibition of JAK1/TYK2 in human M07E cells assessed as reduction of IFN alpha stimulated STAT phosphorylation preincubated for 30 mins followed by IFN alpha stimulation and measured after 15 mins by flow cytometry method
- ChEBML_154356 Binding affinity towards peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEBML_154541 Binding affinity for Peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEMBL_196000 (CHEMBL800489) Binding affinity for Retinoic Acid Receptor gamma (RAR gamma)
- ChEMBL_1722940 (CHEMBL4137940) Inverse agonist activity at RORgammat in human PBMC-derived CD4-positive Th-17 polarized cells assessed as reduction in IL4/anti-IFN-gamma antibody-stimulated IL-17 secretion after 48 to 72 hrs by ELISA
- ChEMBL_1737460 (CHEMBL4153210) Antagonist activity at P2X7 in LPS/IFN gamma differentiated human THP-1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins followed by BzATP stimulation for 30 mins by ELISA
- ChEMBL_2116726 (CHEMBL4825792) Inhibition of TYK2/JAK1 signaling pathway in human whole blood assessed as reduction in IFN-alpha induced STAT3 phosphorylation incubated for 60 mins followed by IFN-alpha addition and measured after 20 mins by fluorescence assay
- ChEMBL_1473820 (CHEMBL3418719) Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins followed by BzATP induction measured after 30 mins by ELISA
- ChEMBL_154356 (CHEMBL759117) Binding affinity towards peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEMBL_154522 (CHEMBL762149) Binding affinity against Peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEMBL_154525 (CHEMBL762152) Binding affinity against peroxisome proliferator activated receptor gamma (PPAR-gamma)
- ChEMBL_2526316 Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFN-alpha-induced STAT1 phosphorylation in monocytes preincubated for 1 hr followed by IFN-alpha stimulation and measured after 8 to 20 mins by FACS analysis
- ChEMBL_1843571 (CHEMBL4343998) Inhibition of STING in human THP1 cells in presence of PFO by IFN reporter gene assay
- ChEMBL_1843574 (CHEMBL4344001) Inhibition of STING in human THP1 cells in presence of digitonin by IFN reporter gene assay
- ChEMBL_1931156 (CHEMBL4434407) Inhibition of TYK2 in human whole blood assessed as reduction in IFN-alpha stimulated TYK2 phosphorylation
- ChEMBL_2094265 (CHEMBL4775528) Inhibition of TYK2 in IFN-alpha stimulated human Kit225 T cells by luciferase reporter gene assay
- ChEMBL_2353683 Inhibition of TYK2 signalling pathway in human PBMC cells assessed as IFN alpha induced p-STAT1 level
- ChEMBL_2353684 Inhibition of TYK2 signalling pathway in human PBMC cells assessed as IFN alpha induced p-STAT3 level
- ChEMBL_1909136 (CHEMBL4411582) Inhibition of JAK1/TYK2 signaling pathway in human lymphocytes of whole blood assessed as reduction in IFN-alpha induced STAT3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition and measured measured after 15 mins by FACS assay
- ChEMBL_2022031 (CHEMBL4675844) Inhibition of JAK1/TYK2 signaling pathway in human whole blood lymphocytes assessed as reduction in IFN-alpha induced STAT3 phosphorylation preincubated for 45 mins followed by IFN-alpha addition and measured measured after 15 mins by FACS assay
- ChEMBL_2240650 (CHEMBL5154546) Inhibition of JAK1/TYK2 signalling in human whole blood assessed as inhibition of IFN-alpha stimulated STAT1 phosphorylation in CD4+ lymphocytes preincubated for 1 hr followed by IFN-alpha stimulation and incubated for 20 mins by flow cytometry analysis
- ChEMBL_2526313 Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFN-alpha-induced STAT1 phosphorylation in CD3+ T cells preincubated for 1 hr followed by IFN-alpha stimulation and measured after 8 to 20 mins by FACS analysis
- ChEMBL_2545852 Inhibition of JAK1/TYK2 signaling pathway in human U2OS cells assessed as reduction in IFN-alphaB2-induced STAT1 phosphorylation preincubated with compound for 1 hr followed by IFN-alphaB2 addition and measured after 1 hr by TR-FRET analysis
- ChEBML_154188 In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEMBL_154215 (CHEMBL759460) Binding affinity against human Peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEMBL_305792 (CHEMBL827980) Inhibition of human Protein kinase C gamma using [gamma-33P]-ATP
- ChEMBL_1933658 (CHEMBL4479310) Antagonist activity at human P2X7 receptor in LPS/IFN-gamma-differentiated human THP-1 cells assessed as suppression of BzATP-stimulated IL-1beta release per-incubated for 30 mins before BzATP addition and measured after 30 mins by ELISA
- ChEMBL_2062459 (CHEMBL4717712) Inhibition of human IDO1 in IFN-gamma-induced human MDA-MB-231 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate pretreated for 4 hrs followed substrate addition measured after 5 hrs by UV-vis spectrophotometric analysis
- ChEMBL_2376406 Inhibition of IDO1 in IFN-gamma-induced human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate preincubated for 24 hrs followed by substrate addition and measured after 30 mins by SpectraMax microplate reader analysis
- ChEBML_153616 In vitro transcription activation on human peroxisome proliferator activated receptor-gamma (PPAR gamma)
- ChEBML_222303 In vitro binding affinity against human PPAR gamma (peroxisome proliferator-activated gamma receptor)
- ChEMBL_2545868 Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFN-alpha-induced STAT1 phosphorylation in CD4+ T cells preincubated with compound for 30 mins followed by IFN-alpha addition and measured after 20 mins by flow cytometry analysis
- ChEMBL_154361 (CHEMBL756623) In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)
- ChEMBL_154548 (CHEMBL757883) In vitro binding affinity against human PPAR gamma (peroxisome proliferator-activated gamma receptor)
- ChEMBL_222303 (CHEMBL841917) In vitro binding affinity against human PPAR gamma (peroxisome proliferator-activated gamma receptor)
- ChEMBL_2184645 (CHEMBL5096727) Antagonist activity at STING (unknown origin) in L929 cells assessed as IFN-beta RNA level q-RTPCR analysis
- ChEBML_154534 Agonist activity against PPAR gamma
- ChEBML_68901 Inhibitory activity against gamma-secretase
- ChEMBL_358169 (CHEMBL854203) Inhibition of gamma secretase
- ChEMBL_364830 (CHEMBL870177) Inhibition of PPAR gamma
- ChEMBL_389284 (CHEMBL868040) Inhibition of PTP gamma
- ChEMBL_438619 (CHEMBL888950) Inhibition of gamma-secretase
- ChEMBL_453103 (CHEMBL902249) Inhibition of Gamma-secretase
- ChEMBL_458481 (CHEMBL941797) Inhibition of PKC gamma
- ChEMBL_458510 (CHEMBL941826) Inhibition of P38 gamma
- ChEMBL_475761 (CHEMBL930277) Inhibition of p38-gamma
- ChEMBL_481048 (CHEMBL997488) Inhibition of PKC gamma
- ChEMBL_489230 (CHEMBL989977) Inhibition of p38beta/gamma
- ChEMBL_509592 (CHEMBL1001353) Inhibition of PI3K gamma
- ChEMBL_582355 (CHEMBL1063392) Inhibition of p38-gamma
- ChEMBL_606945 (CHEMBL1072688) Inhibition of p38-gamma
- ChEMBL_625017 (CHEMBL1109685) Inhibition of p38-gamma
- ChEMBL_627033 (CHEMBL1104515) Inhibition of p38-gamma
- ChEMBL_644879 (CHEMBL1211156) Inhibition of p38-gamma
- ChEMBL_664522 (CHEMBL1259904) Inhibition of PI3K-gamma
- ChEMBL_716959 (CHEMBL1670987) Inhibition of PPAR gamma
- ChEMBL_758493 (CHEMBL1811571) Inhibition of p38-gamma
- ChEMBL_68435 (CHEMBL683047) Binding affinity against Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2
- ChEMBL_70702 (CHEMBL685338) Binding affinity for Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2
- ChEMBL_757720 (CHEMBL1809664) Inhibition of PLK1 assessed as [33P]-gamma-ATP incorporation into substrate by gamma counting
- ChEMBL_2184621 (CHEMBL5096703) Agonist activity to C-terminal domain STING (139 to 379 residues) in human PBMC assessed as IFN-beta secretion
- ChEMBL_2185626 (CHEMBL5097708) Inhibition of cGAS expressed in human THP-1 cells assessed as reduction of IFN-beta expression by ELISA assay
- ChEMBL_2281199 Agonist activity at STING in human THP1-Dual cells assessed as increase in IFN-beta secretion incubated for 24 hrs
- ChEMBL_2354047 Antagonist activity at TLR7 in human Whole blood cell assessed as reduction in IFN-alpha level measured after 30 mins
- ChEMBL_2354048 Antagonist activity at TLR9 in human Whole blood cell assessed as reduction in IFN-alpha level measured after 30 mins
- ChEMBL_302648 (CHEMBL839938) Binding affinity towards gamma-aminobutyric-acid GABA-A receptor alpha-4-beta-3-gamma-2
- ChEMBL_302649 (CHEMBL839939) Binding affinity towards gamma-aminobutyric-acid GABA-A receptor alpha-6-beta-3-gamma-2
- ChEMBL_69813 (CHEMBL678910) Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2
- ChEMBL_757718 (CHEMBL1809662) Inhibition of Aur-A assessed as [33P]-gamma-ATP incorporation into substrate by gamma counting
- ChEMBL_2207934 (CHEMBL5120642) Inhibition of JAK1/TYK2 signaling pathway in human primary T-cells assessed as reduction of IFN-alpha induced STAT1 phosphorylation
- ChEMBL_2354033 Antagonist activity at TLR7 in human PBMC cells assessed as reduction in IFN alpha measured after 20 hrs by AlphaLISA assay
- ChEMBL_2354035 Antagonist activity at TLR9 in human PBMC cells assessed as reduction in IFN alpha measured after 20 hrs by AlphaLISA assay
- ChEBML_153125 Inhibition of protein kinase C-gamma
- ChEBML_153154 Inhibition of protein kinase C gamma
- ChEBML_154532 Activity against murine PPAR gamma receptor
- ChEBML_161146 Inhibition of Protein kinase C gamma
- ChEBML_161147 Inhibition of Protein kinase C gamma
- ChEBML_161148 Inhibition of Protein kinase C gamma
- ChEBML_161284 Inhibition of Protein kinase C gamma
- ChEBML_161285 Inhibition of Protein kinase C gamma
- ChEBML_163495 Effective concentration against RAR-gamma receptor
- ChEMBL_1349386 (CHEMBL3269976) Inhibition of human PPAR-gamma
- ChEMBL_1762449 (CHEMBL4197696) Inhibition of human gamma-secretase
- ChEMBL_208172 (CHEMBL819078) Binding affinity against gamma thrombin
- ChEMBL_2267333 Inhibition of p110 gamma (unknown origin)
- ChEMBL_2272293 Inhibition of gamma-secretase (unknown origin)
- ChEMBL_2272599 Inhibition of PI3K gamma (unknown origin)
- ChEMBL_2294027 Inhibition of gamma-secretase (unknown origin)
- ChEMBL_2422156 Agonist activity at human PPAR gamma
- ChEMBL_2517236 Inhibition of p110 gamma (unknown origin)
- ChEMBL_2583445 Inhibition of PI3K gamma (unknown origin)
- ChEMBL_377005 (CHEMBL868560) Inhibition of DNA polymerase gamma
- ChEMBL_463059 (CHEMBL928969) Inhibition of human p38-gamma
- ChEMBL_612859 (CHEMBL1067548) Inhibition of p38-gamma MAPK
- ChEMBL_655504 (CHEMBL1244548) Binding affinity to p38-gamma
- ChEMBL_687469 (CHEMBL1292145) Inhibition of human PKC-gamma
- ChEMBL_773493 (CHEMBL1839859) Inhibition of recombinant p38-gamma
- Inhibition Assay Inhibition assay using gamma-secretase.
- ChEMBL_154354 (CHEMBL880951) Binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma) was determined by HTRF assay
- ChEMBL_70537 (CHEMBL681094) Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2
- ChEMBL_70714 (CHEMBL682418) Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2
- ChEMBL_757717 (CHEMBL1809661) Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma counting
- ChEMBL_757719 (CHEMBL1809663) Inhibition of CDK2/Cyclin A assessed as [33P]-gamma-ATP incorporation into substrate by gamma counting
- ChEMBL_2452064 Inhibition of PI3K p110-gamma (unknown origin) in presence of [gamma-32P]ATP by radioactivity based kinase assay
- ChEMBL_631390 (CHEMBL1109142) Inhibition of Plk2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631391 (CHEMBL1109143) Inhibition of Plk3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631403 (CHEMBL1109155) Inhibition of VEGFR3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631405 (CHEMBL1109157) Inhibition of KIT assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631407 (CHEMBL1109159) Inhibition of AKT1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631408 (CHEMBL1109160) Inhibition of ALK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631410 (CHEMBL1109162) Inhibition of CDC7 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631411 (CHEMBL1109163) Inhibition of CDK7 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631413 (CHEMBL1111118) Inhibition of CHK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631415 (CHEMBL1111952) Inhibition of ERK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631416 (CHEMBL1111953) Inhibition of FGFR1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631417 (CHEMBL1111954) Inhibition of IGF1R assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631419 (CHEMBL1111956) Inhibition of IKK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631421 (CHEMBL1111958) Inhibition of LCK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631422 (CHEMBL1111959) Inhibition of MAPKAPK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631423 (CHEMBL1111960) Inhibition of MET assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631424 (CHEMBL1111961) Inhibition of NEK6 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631426 (CHEMBL1111963) Inhibition of PAK4 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631427 (CHEMBL1111964) Inhibition of PDK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631430 (CHEMBL1111967) Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631431 (CHEMBL1111968) Inhibition of RET assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631432 (CHEMBL1111969) Inhibition of STK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631434 (CHEMBL1111971) Inhibition of TrkA assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631617 (CHEMBL1106611) Inhibition of VEGFR2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_68433 (CHEMBL683045) Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-6-beta-3-gamma-2
- ChEMBL_69814 (CHEMBL678911) Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2
- ChEMBL_70099 (CHEMBL678329) Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2
- ChEMBL_70261 (CHEMBL681248) Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2
- ChEMBL_70416 (CHEMBL682251) Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2
- ChEMBL_70695 (CHEMBL681480) Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2
- ChEMBL_745831 (CHEMBL1776201) Inhibition of NEK6 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745832 (CHEMBL1776202) Inhibition of NIM1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745833 (CHEMBL1776203) Inhibition of P38alpha assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745834 (CHEMBL1776204) Inhibition of PAK4 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745836 (CHEMBL1776206) Inhibition of PDK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745837 (CHEMBL1776207) Inhibition of EphA2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745838 (CHEMBL1776208) Inhibition of ERK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745839 (CHEMBL1776209) Inhibition of FAK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745840 (CHEMBL1776210) Inhibition of FGFR1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745842 (CHEMBL1776212) Inhibition of Haspin assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745843 (CHEMBL1776213) Inhibition of IGFR1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745844 (CHEMBL1776214) Inhibition of IKK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745845 (CHEMBL1776215) Inhibition of IR assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745846 (CHEMBL1776216) Inhibition of JAK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745847 (CHEMBL1776217) Inhibition of JAK3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745848 (CHEMBL1776218) Inhibition of KIT assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745849 (CHEMBL1776219) Inhibition of LCK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745850 (CHEMBL1776220) Inhibition of LYN assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745851 (CHEMBL1776221) Inhibition of MAPKAPK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745852 (CHEMBL1776222) Inhibition of MET assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745853 (CHEMBL1776223) Inhibition of MNK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745854 (CHEMBL1776224) Inhibition of MPS1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745855 (CHEMBL1776225) Inhibition of MST4 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745933 (CHEMBL1776303) Inhibition of PERK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745934 (CHEMBL1776304) Inhibition of PIM1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745935 (CHEMBL1776305) Inhibition of PIM2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745936 (CHEMBL1776306) Inhibition of PKAalpha assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745937 (CHEMBL1776307) Inhibition of PKCbeta assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745938 (CHEMBL1776308) Inhibition of RET assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745939 (CHEMBL1776309) Inhibition of ROS1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745941 (CHEMBL1775240) Inhibition of Syk assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745942 (CHEMBL1775241) Inhibition of TLK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745943 (CHEMBL1775242) Inhibition of TRKA assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745944 (CHEMBL1775243) Inhibition of TYK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745945 (CHEMBL1775244) Inhibition of VEGFR2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745946 (CHEMBL1775245) Inhibition of VEGFR3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745947 (CHEMBL1775246) Inhibition of ZAP70 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747145 (CHEMBL1777511) Inhibition of PLK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747146 (CHEMBL1777512) Inhibition of PLK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747147 (CHEMBL1777513) Inhibition of PLK3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747248 (CHEMBL1776507) Inhibition of FLT3 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747249 (CHEMBL1776508) Inhibition of MELK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747251 (CHEMBL1776510) Inhibition of ABL assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747252 (CHEMBL1776511) Inhibition of ACK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747253 (CHEMBL1776512) Inhibition of AKT1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747254 (CHEMBL1776513) Inhibition of ALK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747257 (CHEMBL1776516) Inhibition of BRK assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747258 (CHEMBL1776517) Inhibition of BUB1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747265 (CHEMBL1776524) Inhibition of CHK1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747266 (CHEMBL1776525) Inhibition of EEF2K assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_1684603 (CHEMBL4035082) Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA
- ChEMBL_2184622 (CHEMBL5096704) Agonist activity to C-terminal domain STING HAQ mutant (139 to 379 residues) in human PBMC assessed as IFN-beta secretion
- ChEMBL_2354049 Antagonist activity at TLR7 in mouse Splenocyte assessed as reduction in IFN-alpha level measured after 20 hrs by Spectramax M5 method
- ChEMBL_2354050 Antagonist activity at TLR9 in mouse Splenocyte assessed as reduction in IFN-alpha level measured after 20 hrs by Spectramax M5 method
- ChEBML_147141 Binding affinity for gamma-S binding assay
- ChEBML_161272 Inhibition of human Protein kinase C gamma
- ChEBML_161274 Inhibition of human Protein kinase C gamma
- ChEBML_196013 Binding affinity towards Retinoic acid receptor gamma
- ChEBML_196319 Binding affinity against Retinoic acid receptor gamma
- ChEBML_196322 Binding affinity for Retinoic acid receptor gamma
- ChEBML_196329 Binding affinity against Retinoic acid receptor gamma
- ChEBML_306114 In vitro binding affinity for PPAR-gamma
- ChEBML_68902 Inhibitory concentration against gamma-secretase was determined
- ChEMBL_1365495 (CHEMBL3297010) Inhibition of human DNA polymerase gamma
- ChEMBL_1450781 (CHEMBL3363926) Inhibition of PI3K-gamma (unknown origin)
- ChEMBL_153124 (CHEMBL758470) Inhibition of protein kinase C gamma
- ChEMBL_153154 (CHEMBL761877) Inhibition of protein kinase C gamma
- ChEMBL_154187 (CHEMBL762736) Transcriptional activation by human PPAR gamma
- ChEMBL_154211 (CHEMBL759456) Inhibitory concentration of the PPAR gamma)
- ChEMBL_1583672 (CHEMBL3815759) Inhibition of PI3K gamma (unknown origin)
- ChEMBL_161143 (CHEMBL767411) Inhibition of protein kinase C gamma
- ChEMBL_161145 (CHEMBL767413) Inhibition of Protein kinase C gamma
- ChEMBL_161146 (CHEMBL767414) Inhibition of Protein kinase C gamma
- ChEMBL_161284 (CHEMBL766914) Inhibition of Protein kinase C gamma
- ChEMBL_163481 (CHEMBL772394) Transcriptional activation for RAR gamma receptor
- ChEMBL_1762453 (CHEMBL4197700) Inhibition of gamma-secretase (unknown origin)
- ChEMBL_1925267 (CHEMBL4428339) Inhibition of gamma secretase (unknown origin)
- ChEMBL_2026875 (CHEMBL4681033) Agonist activity at human PPAR-gamma
- ChEMBL_2199021 (CHEMBL5111537) Inhibition of human DNA polymerase gamma
- ChEMBL_220901 (CHEMBL824656) Binding affinity at human PPAR gamma
- ChEMBL_339276 (CHEMBL867229) Binding affinity to human PPAR gamma
- ChEMBL_424080 (CHEMBL855083) Displacement of Fluormone from PPAR gamma
- ChEMBL_473713 (CHEMBL939369) Inhibition of p38-gamma MAP kinase
- ChEMBL_476359 (CHEMBL921519) Binding affinity at PPAR gamma receptor
- ChEMBL_533421 (CHEMBL983382) Inhibition of human DNA polymerase gamma
- ChEMBL_537070 (CHEMBL986219) Binding affinity to human p38-gamma
- ChEMBL_68895 (CHEMBL678617) Inhibition of human gamma-secretase activity
- ChEMBL_68900 (CHEMBL676871) In vitro inhibition of gamma secretase.
- ChEMBL_720298 (CHEMBL1679164) Inhibition of human DNA polymerase gamma
- ChEMBL_941101 (CHEMBL2330898) Inhibition of PKC gamma (unknown origin)
- ChEMBL_154377 (CHEMBL758986) in vitro agonist activity against peroxisome proliferator activated receptor-gamma (PPAR-gamma), using alkaline phosphatase activity transactivator assay
- ChEMBL_558101 (CHEMBL956591) Displacement of [3H]GHB from gamma-hydroxybutyrate binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranes
- ChEMBL_631394 (CHEMBL1109146) Inhibition of Aurora A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631401 (CHEMBL1109153) Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631406 (CHEMBL1109158) Inhibition of c-ABL assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631409 (CHEMBL1109161) Inhibition of Aurora B assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631418 (CHEMBL1111955) Inhibition of GSK3-beta assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631420 (CHEMBL1111957) Inhibition of insulin receptor assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631428 (CHEMBL1111965) Inhibition of PKA-alpha assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631429 (CHEMBL1111966) Inhibition of PKC-beta assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_745841 (CHEMBL1776211) Inhibition of GSK3-beta assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747255 (CHEMBL1776514) Inhibition of Aur-A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747256 (CHEMBL1776515) Inhibition of Aur-B assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747259 (CHEMBL1776518) Inhibition of CDC7/DBF4 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747260 (CHEMBL1776519) Inhibition of CDK1/CYCB assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747261 (CHEMBL1776520) Inhibition of CDK2/CYCA assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747262 (CHEMBL1776521) Inhibition of CDK2/CYCE assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747263 (CHEMBL1776522) Inhibition of CDK4/CYCD1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_747264 (CHEMBL1776523) Inhibition of CDK5/P25 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEBML_1684604 Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA
- ChEMBL_2184606 (CHEMBL5096688) Agonist activity at STING in human L929 cells assessed as IFN-beta RNA level measured after 4 hrs by qRT-PCR analysis
- ChEMBL_2322395 Activation of STING signalling pathway in human PBMC cells assessed as increase in IFN-beta level incubated for 4 hrs by ELISA method
- ChEMBL_2354052 Antagonist activity at TLR7 in mouse Whole blood cell assessed as reduction in IFN-alpha level measured after 20 hrs by AlphaLISA method
- ChEMBL_2354053 Antagonist activity at TLR9 in mouse Whole blood cell assessed as reduction in IFN-alpha level measured after 20 hrs by AlphaLISA method
- ChEMBL_631393 (CHEMBL1109145) Inhibition of CDK2/Cyclin A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631400 (CHEMBL1109152) Inhibition of CDK1/Cyclin B assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631402 (CHEMBL1109154) Inhibition of CDK2/Cyclin E assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631412 (CHEMBL1111117) Inhibition of CDK4/Cyclin D1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_631414 (CHEMBL1111951) Inhibition of EGFR isoform 1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_68434 (CHEMBL683046) Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2
- ChEMBL_70256 (CHEMBL682715) Agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes
- ChEMBL_70411 (CHEMBL682825) Agonist activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes
- ChEMBL_70701 (CHEMBL685337) Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2
- ChEMBL_1684604 (CHEMBL4035083) Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA
- ChEMBL_1989204 (CHEMBL4622751) Antagonist activity at TLR9 in human pDC assessed as inhibition of ODN2216-induced IFN-alpha production incubated for 24 hrs measured by ELISA
- ChEMBL_2198049 (CHEMBL5110565) Agonist activity at STING in human THP-1 cells assessed as increase in IFN-beta secretion incubated for 5 hrs by AlphaLISA assay
- ChEBML_139553 Activation of murine PPAR gamma ligand binding domain
- ChEBML_153232 Maximum transcriptional activation of human PPAR gamma receptor
- ChEBML_196016 Binding affinity towards human Retinoic acid receptor gamma
- ChEBML_196170 Transcriptional activation of retinoic acid receptor RAR gamma
- ChEBML_70524 Binding affinity for retinoic acid receptor RAR gamma
- ChEBML_70528 Binding affinity for retinoic acid receptor RAR gamma
- ChEMBL_1442318 (CHEMBL3377679) Binding affinity to PPAR-gamma (unknown origin)
- ChEMBL_153629 (CHEMBL762525) In vitro transcriptional activation by PPAR gamma
- ChEMBL_153632 (CHEMBL762528) In vitro transcriptional activation by PPAR gamma
- ChEMBL_153634 (CHEMBL762530) Final binding affinity against PPAR-gamma receptor
- ChEMBL_153635 (CHEMBL762531) Initial binding affinity against PPAR-gamma receptor
- ChEMBL_161274 (CHEMBL772955) Inhibition of human Protein kinase C gamma
- ChEMBL_161278 (CHEMBL772959) Inhibition of Protein kinase C gamma (PKC)
- ChEMBL_1721611 (CHEMBL4136611) Inhibition of cystathionine gamma-lyase (unknown origin)
- ChEMBL_195999 (CHEMBL800488) Binding affinity for Retinoic acid receptor gamma
- ChEMBL_196001 (CHEMBL800490) Binding affinity for Retinoic acid receptor gamma
- ChEMBL_196006 (CHEMBL797870) Agonistic activity towards retinoic acid receptor-gamma
- ChEMBL_196007 (CHEMBL797871) Antagonistic activity towards retinoic acid receptor-gamma
- ChEMBL_196015 (CHEMBL798025) Selective activity towards retinoic acid receptor-gamma
- ChEMBL_196308 (CHEMBL805023) Transactivation potency for Retinoic acid receptor gamma
- ChEMBL_196322 (CHEMBL806265) Binding affinity for Retinoic acid receptor gamma
- ChEMBL_196640 (CHEMBL800753) Agonistic activity towards retinoid X receptor-gamma
- ChEMBL_196641 (CHEMBL800754) Antagonistic activity towards retinoid X receptor-gamma
- ChEMBL_196642 (CHEMBL800755) Selective activity towards retinoid X receptor-gamma
- ChEMBL_196643 (CHEMBL800756) Synergistic activity towards retinoid X receptor-gamma
- ChEMBL_306114 (CHEMBL830065) In vitro binding affinity for PPAR-gamma
- ChEMBL_320732 (CHEMBL880877) Dissociation constant for Retinoic acid receptor gamma
- ChEMBL_439784 (CHEMBL888894) Displacement of [3H]rosiglitazone from PPAR gamma
- ChEMBL_531813 (CHEMBL991525) Antagonist activity at protein kinase C gamma
- ChEMBL_543160 (CHEMBL1014320) Inhibition of gamma-glutamyltranspeptidase by colorimetric assay
- ChEMBL_586604 (CHEMBL1061183) Binding constant for full-length p38-gamma
- ChEMBL_774246 (CHEMBL1908463) Binding constant for p38-gamma kinase domain
- ChEMBL_978823 (CHEMBL2423425) Inhibition of PI-3K gamma (unknown origin)
- ChEMBL_434338 (CHEMBL919396) Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding
- ChEMBL_70095 (CHEMBL678325) Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytes
- ChEMBL_70691 (CHEMBL679474) Effective agonist dose for human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytes
- ChEMBL_1831743 (CHEMBL4331751) Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFN-alpha stimulated TYK2 phosphorylation by caspase3/7 reagent-based Western blot analysis
- ChEMBL_1831744 (CHEMBL4331752) Inhibition of JAK1 in human Jurkat cells assessed as reduction in IFN-alpha stimulated JAK1 phosphorylation by caspase3/7 reagent-based Western blot analysis
- ChEMBL_1831745 (CHEMBL4331753) Inhibition of JAK2 in human Jurkat cells assessed as reduction in IFN-alpha stimulated JAK2 phosphorylation by caspase3/7 reagent-based Western blot analysis
- ChEMBL_1831746 (CHEMBL4331754) Inhibition of JAK3 in human Jurkat cells assessed as reduction in IFN-alpha stimulated JAK3 phosphorylation by caspase3/7 reagent-based Western blot analysis
- ChEMBL_70090 (CHEMBL677036) Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2
- ChEMBL_70252 (CHEMBL682711) Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2
- ChEMBL_70257 (CHEMBL681244) Effective dose for agonist activity on human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 in Xenopus oocytes
- ChEMBL_70407 (CHEMBL680434) Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2
- ChEMBL_70552 (CHEMBL680671) Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-5-beta-3-gamma-2
- ChEBML_161307 Binding affinity for protein kinase C gamma-C1B domain
- ChEBML_196331 Inhibition of [3H]ATRA binding to RAR gamma receptor
- ChEBML_221639 Inhibition of p56 lck autophosphorylation, gamma-[33P]ATP incorporation
- ChEMBL_147142 (CHEMBL754174) Binding affinity for gamma-S binding assay; Inactive
- ChEMBL_153232 (CHEMBL764465) Maximum transcriptional activation of human PPAR gamma receptor
- ChEMBL_154518 (CHEMBL764404) Transcriptional activation of peroxisome proliferator activated receptor gamma
- ChEMBL_154539 (CHEMBL760259) Binding affinity for peroxisome proliferator activated receptor gamma
- ChEMBL_1563455 (CHEMBL3783048) Agonist activity at PPAR-gamma receptor (unknown origin)
- ChEMBL_195987 (CHEMBL807693) Transcriptional activation of Retinoic acid receptor RAR gamma
- ChEMBL_195988 (CHEMBL879244) Transcriptional activation of Retinoic acid receptor RAR gamma
- ChEMBL_196157 (CHEMBL804930) Transcriptional activation of Retinoic acid receptor RAR gamma
- ChEMBL_196160 (CHEMBL804933) Transcriptional activation of Retinoic acid receptor RAR gamma
- ChEMBL_196170 (CHEMBL804943) Transcriptional activation of retinoic acid receptor RAR gamma
- ChEMBL_196178 (CHEMBL804951) Transcriptional activation of Retinoic acid receptor RAR gamma
- ChEMBL_196667 (CHEMBL803399) Transcriptional activation of Retinoic acid receptor RAR gamma
- ChEMBL_197216 (CHEMBL798964) Transcriptional activation of Retinoid X receptor RXR gamma
- ChEMBL_197219 (CHEMBL798967) Transcriptional activation of Retinoid X receptor RXR gamma
- ChEMBL_197233 (CHEMBL801379) Transcriptional activation of Retinoid X receptor RXR gamma
- ChEMBL_197234 (CHEMBL801380) Effective concentrations against Retinoic acid receptor RXR-gamma
- ChEMBL_197243 (CHEMBL803365) Binding affinity towards Retinoic acid receptor RXR-gamma
- ChEMBL_2267394 Inhibition of human gamma secretase by western blot assay
- ChEMBL_2494610 Agonist activity at full length ERR-gamma (unknown origin)
- ChEMBL_2521088 Inhibition of peroxisome proliferator-activated receptors gamma (unknown origin)
- ChEMBL_305937 (CHEMBL833484) Inhibition of human Peroxisome proliferator activated receptor gamma
- ChEMBL_306190 (CHEMBL830984) In vitro binding affinity for human PPAR gamma
- ChEMBL_320735 (CHEMBL881208) Binding affinity towards peroxisome proliferator activated receptor gamma
- ChEMBL_339279 (CHEMBL868414) Transactivation by human PPAR gamma in COS1 cells
- ChEMBL_643027 (CHEMBL1176541) Binding affinity to human NTR1 by gamma counting
- ChEMBL_643028 (CHEMBL1176542) Binding affinity to human NTR2 by gamma counting
- ChEMBL_68428 (CHEMBL682874) Inhibition of Gamma-aminobutyric acid type B receptor
- ChEMBL_70524 (CHEMBL681081) Binding affinity for retinoic acid receptor RAR gamma
- ChEMBL_70649 (CHEMBL678640) Binding affinity against Gamma-amino-N-butyrate transaminase
- ChEMBL_70659 (CHEMBL678649) Inhibitory activity against Gamma-amino-N-butyrate transaminase
- ChEMBL_951390 (CHEMBL2349764) Inhibition of human FAK using [gamma-33P]ATP
- ChEMBL_1989205 (CHEMBL4622752) Antagonist activity at TLR7 in human pDC assessed as inhibition of inactivated flu-virus induced IFN-alpha production incubated for 24 hrs measured by ELISA
- ChEMBL_2322376 Activation of STING signalling pathway in human wild type THP-1 cells assessed as increase in IFN-beta secretion incubated for 4 hrs by ELISA method
- ChEMBL_154529 (CHEMBL760250) In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assay (SPA)
- ChEMBL_2452108 Inhibition of human recombinant PI3K p110-gamma incubated for 120 mins in presence of [gamma-33P]ATP by radioactivity based scintillation proximity assay
- ChEMBL_68432 (CHEMBL683044) Antagonistic potency against human Gamma-aminobutyric acid A receptor alpha-6-beta-3-gamma-2 expressed in Xenopus oocytes at 1 mM
- ChEMBL_70098 (CHEMBL678328) Antagonistic potency against human Gamma-aminobutyric acid A receptor alpha-1-beta-3-gamma-2 expressed in Xenopus oocytes at 1 mM
- ChEMBL_70106 (CHEMBL681641) Binding affinity to human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2, determined using [3H]-Ro- 15-1788 radioligand
- ChEMBL_70260 (CHEMBL681247) Antagonistic potency against human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 expressed in Xenopus oocytes at 1 mM
- ChEMBL_70415 (CHEMBL682250) Antagonistic potency against human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes at 1 mM
- ChEMBL_70538 (CHEMBL681095) Antagonistic potency against human Effective dose for agonist activity on human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2
- ChEMBL_70539 (CHEMBL682901) Antagonistic potency against human Effective dose for agonist activity on human Gamma-aminobutyric acid A receptor alpha-4-beta-3-gamma-2
- ChEMBL_70694 (CHEMBL679477) Antagonistic potency against human Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in Xenopus oocytes at 1 mM
- ChEMBL_303742 (CHEMBL829785) Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 expressed in HEK293 cells
- ChEMBL_303743 (CHEMBL829786) Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-2-beta-2-gamma-2 expressed in HEK293 cells
- ChEMBL_303744 (CHEMBL829787) Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in HEK293 cells
- ChEMBL_70266 (CHEMBL681405) Binding affinity to human gamma-amino butyric-acid A receptor alpha-2-beta-3-gamma-2, using a [3H]-Ro- 15-1788 radioligand
- ChEMBL_70418 (CHEMBL682253) Binding affinity to human gamma-amino butyric-acid A receptor alpha-3-beta-3-gamma-2, using a [3H]-Ro- 15-1788 radioligand
- ChEMBL_2363663 Inhibition of JAK1/2-mediated STAT1 phosphorylation in human M07E cells preincubated for 30 mins followed by IFN-alpha stimulation measured after 15 mins by flow cytometry
- ChEBML_154201 Peroxisome proliferator activated receptor gamma agonistic activity in HepG2 cells.
- ChEBML_154209 In vitro binding affinity for human PPAR gamma in SPA
- ChEBML_68750 Compound was tested for inhibitory potency against gamma-Glutamyl Hydrolase.
- ChEMBL_153619 (CHEMBL760384) Displacement of PPARgamma agonist from human PPAR gamma receptor
- ChEMBL_154051 (CHEMBL760856) Agonistic activity for human Peroxisome proliferator activated receptor gamma
- ChEMBL_161277 (CHEMBL772958) Inhibition of human Protein kinase C gamma with [Ca2+]
- ChEMBL_161286 (CHEMBL766916) Inhibition of Protein kinase C gamma at 1 uM
- ChEMBL_161293 (CHEMBL772101) Binding affinity for Protein kinase C gamma C1a domain
- ChEMBL_161299 (CHEMBL772107) Binding affinity for Protein kinase C gamma C1b domain
- ChEMBL_161305 (CHEMBL772113) Binding affinity for protein kinase C gamma-C1A domain
- ChEMBL_161307 (CHEMBL772115) Binding affinity for protein kinase C gamma-C1B domain
- ChEMBL_1625827 (CHEMBL3868296) Inhibition of PI3K-gamma (unknown origin) by KinaseGlo assay
- ChEMBL_1762450 (CHEMBL4197697) Inhibition of human gamma-secretase by cell based assay
- ChEMBL_1925268 (CHEMBL4428340) Inhibition of gamma secretase (unknown origin) mediated Notch signaling
- ChEMBL_1925288 (CHEMBL4428360) Inhibition of gamma secretase (unknown origin) mediated Notch activation
- ChEMBL_196165 (CHEMBL804938) Inhibition of binding to retinoid A receptor RAR gamma
- ChEMBL_196166 (CHEMBL804939) Dissociation constant for binding to Retinoic acid receptor gamma
- ChEMBL_196331 (CHEMBL801568) Inhibition of [3H]ATRA binding to RAR gamma receptor
- ChEMBL_197227 (CHEMBL798203) Dissociation constant for binding to Retinoid X receptor gamma
- ChEMBL_2019878 (CHEMBL4673691) Inhibition of PI3K-gamma (unknown origin) by HTRF assay
- ChEMBL_2213986 (CHEMBL5127118) Inhibition of ROR gamma (unknown origin) by FRET analysis
- ChEMBL_2538106 Inhibition of human p38-gamma by discoverX kinome scan assay
- ChEMBL_2583448 Inhibition of PI3K gamma (unknown origin) by membrane capture assay
- ChEMBL_302915 (CHEMBL830375) Binding affinity for murine peroxisome proliferator activated receptor gamma
- ChEMBL_302951 (CHEMBL841786) Binding affinity for human peroxisome proliferator activated receptor gamma
- ChEMBL_304205 (CHEMBL829745) Effective concentration against human Peroxisome proliferator activated receptor gamma
- ChEMBL_304215 (CHEMBL829755) Effective concentration for human peroxisome proliferator-activated receptor gamma
- ChEMBL_304468 (CHEMBL832684) Agonist response against human PPAR gamma in transactivation assay
- ChEMBL_306293 (CHEMBL828585) Inhibition of human Peroxisome proliferator activated receptor gamma binding
- ChEMBL_306696 (CHEMBL830853) Inhibition of human peroxisome proliferator activated receptor gamma binding
- ChEMBL_321366 (CHEMBL881510) Inhibitory concentration against mitogen-activated protein kinase p38-gamma
- ChEMBL_327489 (CHEMBL861781) Activity against PPAR gamma in human by FRET assay
- ChEMBL_376900 (CHEMBL871385) Inhibition of gamma secretase expressed in SH-SY5Y cells
- ChEMBL_440752 (CHEMBL889849) Inhibition of gamma secretase-mediated amyloid-beta peptid aggregation
- ChEMBL_447416 (CHEMBL896440) Inhibition of gamma secretase in APP-transfected CHO cells
- ChEMBL_463298 (CHEMBL930799) Inhibition of human gamma secretase in human SHSY5Y cells
- ChEMBL_70647 (CHEMBL678638) Concentration dependent inactivation of Gamma-amino-N-butyrate transaminase
- ChEMBL_70656 (CHEMBL678646) The Dissociation Constant for Gamma-amino-N-butyrate transaminase
- ChEMBL_756564 (CHEMBL1804637) Inhibition of human Nek2 in using [gamma-32P] ATP
- ChEMBL_767530 (CHEMBL1825642) Inhibition of CDK9 by [33P]gamma-ATP incorporation assay
- ChEMBL_789438 (CHEMBL1924414) Displacement of [125I]galanin from GalR1 by gamma counting
- ChEMBL_789439 (CHEMBL1924415) Displacement of [125I]galanin from GalR2 by gamma counting
- ChEMBL_839974 (CHEMBL2090370) Inhibition of PI3K gamma by continuous TR-FRET assay
- ChEMBL_951382 (CHEMBL2349756) Inhibition of YES (unknown origin) using [gamma-33P]ATP
- ChEMBL_951384 (CHEMBL2349758) Inhibition of MLK1 (unknown origin) using [gamma-33P]ATP
- ChEMBL_951385 (CHEMBL2349759) Inhibition of HGK (unknown origin) using [gamma-33P]ATP
- ChEMBL_951386 (CHEMBL2349760) Inhibition of MLCK (unknown origin) using [gamma-33P]ATP
- ChEMBL_951387 (CHEMBL2349761) Inhibition of GCK (unknown origin) using [gamma-33P]ATP
- ChEMBL_951388 (CHEMBL2349762) Inhibition of FGR (unknown origin) using [gamma-33P]ATP
- ChEMBL_951389 (CHEMBL2349763) Inhibition of FYN (unknown origin) using [gamma-33P]ATP
- ChEMBL_951391 (CHEMBL2349765) Inhibition of CHK2 (unknown origin) using [gamma-33P]ATP
- ChEMBL_631389 (CHEMBL1109141) Inhibition of GST-tagged PLK1 expressed in H5 insect cells assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_70250 (CHEMBL682709) Binding affinity towards human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2 using [3H]Ro-151788 expressed in L(tk-) cells
- ChEMBL_70262 (CHEMBL681249) Displacement of [3H]Ro-151788 from human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 stably expressed in L(tk-) cells
- ChEMBL_70405 (CHEMBL680432) Binding affinity towards human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 using [3H]Ro-151788 expressed in L(tk-) cells
- ChEMBL_70410 (CHEMBL682824) Effective dose for agonist activity on activity on human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expressed in Xenopus oocytes
- ChEMBL_808454 (CHEMBL1961030) Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
- ChEMBL_2198046 (CHEMBL5110562) Agonist activity at human wild type haplotype STING in human PBMC cells assessed as increase in IFN-beta secretion incubated for 3 hrs by luminescence based analysis
- ChEBML_154360 Binding affinity was determined by displacement of 20 nM [3H]- thiazolidinedione from 4 nM biotinylated human Peroxisome proliferator activated receptor gamma (PPAR gamma) ligand binding domain
- ChEMBL_303793 (CHEMBL829842) Displacement of [3H]-Ro- 15-1788 from human gamma-aminobutyric-acid GABA-A receptor alpha-1-beta-3-gamma-2 expressed in L(tk-) cells
- ChEMBL_303794 (CHEMBL829843) Displacement of [3H]-Ro- 15-1788 from human gamma-aminobutyric-acid GABA-A receptor alpha-2-beta-3-gamma-2 expressed in L(tk-) cells
- ChEMBL_303795 (CHEMBL829844) Displacement of [3H]-Ro- 15-1788 from human gamma-aminobutyric-acid GABA-A receptor alpha-3-beta-3-gamma-2 expressed in L(tk-) cells
- ChEMBL_303796 (CHEMBL829845) Displacement of [3H]-Ro- 15-1788 from human gamma-aminobutyric-acid GABA-A receptor alpha-5-beta-3-gamma-2 expressed in L(tk-) cells
- ChEMBL_911966 (CHEMBL3058797) Inhibition of Setaria cervi Gamma-glutamyltranspeptidase using L-gamma-glutamyl-p-nitroanilide as substrate incubated for 15 min prior to substrate addition by spectrophotometric analysis
- ChEMBL_2349430 Inhibition of TYK2 in HEK-Blue alpha/beta cells pretreated for 60 mins followed by IFN-alpha stimulation for 16 to 18 hrs by Quanti-Blue based SEAP assay
- ChEBML_154050 Agonist activity against human peroxisome proliferator activated receptor gamma was determined
- ChEBML_154208 In vitro binding affinity against human peroxisome proliferator activated receptor gamma
- ChEBML_196014 Inhibition of [3H]RA to binding Retinoic acid receptor RAR gamma
- ChEBML_68572 Inhibition of mammalian Gamma-aminobutyric acid type B receptor (potent agonist)
- ChEBML_70657 Apparent dissociation constants for inactivation of Gamma-amino-N-butyrate transaminase
- ChEBML_70671 Binding affinity against Gamma-amino-N-butyrate transaminase in pig brain
- ChEMBL_154209 (CHEMBL759454) In vitro binding affinity for human PPAR gamma in SPA
- ChEMBL_1546996 (CHEMBL3748099) Inhibition of human ALK5 in presence of (33P)gamma ATP
- ChEMBL_1546997 (CHEMBL3748100) Inhibition of human KDR in presence of (33P)gamma ATP
- ChEMBL_1546999 (CHEMBL3748102) Inhibition of human ALK2 in presence of (33P)gamma ATP
- ChEMBL_1762445 (CHEMBL4197692) Inhibition of gamma-secretase (unknown origin) assessed as notch cleavage
- ChEMBL_196164 (CHEMBL804937) Inhibition of binding to murine Retinoic acid receptor RAR gamma
- ChEMBL_196325 (CHEMBL806268) Binding constant for baculovirus-expressed Retinoic acid receptor RAR gamma
- ChEMBL_196327 (CHEMBL806270) In vitro binding affinity for Retinoic acid receptor RAR gamma
- ChEMBL_197224 (CHEMBL798972) Inhibition of binding to murine Retinoid X receptor RXR gamma
- ChEMBL_197225 (CHEMBL798334) Inhibition of binding to murine Retinoid X receptor RXR gamma
- ChEMBL_2422154 Agonist activity at human PPAR gamma by luciferase reporter gene assay
- ChEMBL_2456061 Binding affinity to human DNA polymerase gamma assessed as inhibition constant
- ChEMBL_2544454 Inhibition of PLK1 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544455 Inhibition of PLK2 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544456 Inhibition of PLK3 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544457 Inhibition of FLT3 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544458 Inhibition of MELK (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544459 Inhibition of CK2 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544460 Inhibition of ABL (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544461 Inhibition of ACK1 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544462 Inhibition of AKT1 (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_2544463 Inhibition of ALK (unknown origin) in presence of [gamma-33P]ATP
- ChEMBL_305529 (CHEMBL828550) Inhibitory activity against Gamma-secretase from APP-transfected CHO cells
- ChEMBL_305707 (CHEMBL827222) In vitro inhibition of human Peroxisome proliferator activated receptor gamma
- ChEMBL_310661 (CHEMBL838008) Maximal intrinsic response against peroxisome proliferator activated receptor gamma transactivation
- ChEMBL_352177 (CHEMBL867852) Displacement of [3H]phorbol 12,13-dibutyrate from PKC gamma-C1A
- ChEMBL_352178 (CHEMBL869658) Displacement of [3H]phorbol 12,13-dibutyrate from PKC gamma-C1B
- ChEMBL_354055 (CHEMBL870009) Inhibition of LPS/interferon gamma-stimulated TNFalpha release from HPBMC
- ChEMBL_430029 (CHEMBL917205) Inhibition of gamma secretase isolated from HeLa cells by ELISA
- ChEMBL_44334 (CHEMBL651610) Transcriptional activity against RXR:PPAR-gamma synergy was determined in vitro
- ChEMBL_589589 (CHEMBL1052142) Inhibition of recombinant CHK2 by [gamma-33P]ATP based assay
- ChEMBL_589590 (CHEMBL1052143) Inhibition of recombinant MET by [gamma-33P]ATP based assay
- ChEMBL_591797 (CHEMBL1041537) Inhibition of FGFR3 by [gamma-33-P]ATP based assay
- ChEMBL_591798 (CHEMBL1041538) Inhibition of PDGFRalpha by [gamma-33-P]ATP based assay
- ChEMBL_591799 (CHEMBL1041539) Inhibition of PDGFRbeta by [gamma-33-P]ATP based assay
- ChEMBL_591800 (CHEMBL1041540) Inhibition of TIE2 by [gamma-33-P]ATP based assay
- ChEMBL_591805 (CHEMBL1041545) Inhibition of Lck by [gamma-33-P]ATP based assay
- ChEMBL_643026 (CHEMBL1176540) Displacement of [125I]NT from rat NTR2 by gamma counting
- ChEMBL_665132 (CHEMBL1260395) Inhibition of [3H]PDBu binding to PKC gamma C1A peptide
- ChEMBL_68414 (CHEMBL680330) Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5
- ChEMBL_885943 (CHEMBL2215705) Inhibition of GSK3beta using [gamma-33P]ATP by AlphaScreen analysis