Query String: PPARgamma agonist
US10806720, Compound Enobosarm-(agonist) BDBM50529668 US11648234, Compound Enobosarm-(agonist) Ostarine MK-2866 Gtx-024 US11230523, Compound Enobosarm-(agonist) Enobosarm
Adenosine receptor agonist, 7 BDBM200211
Adenosine receptor agonist, 9 BDBM200213
BDBM200215 Adenosine receptor agonist, 11
BDBM200216 Adenosine receptor agonist, 13
BDBM200217 Adenosine receptor agonist, 14
BDBM85137 CCK-A Agonist 45
BDBM85140 CCK-A Agonist 32
BDBM85141 CCK-A Agonist 24
BDBM85142 CCK-A Agonist 42
BDBM85143 CCK-A Agonist 34
BDBM85146 CCK-A Agonist 30
BDBM85147 CCK-A Agonist 22
BDBM85148 CCK-A Agonist 21
BDBM85149 CCK-A Agonist 33
BDBM85150 CCK-A Agonist 25
BDBM85151 CCK-A Agonist 18
BDBM85152 CCK-A Agonist 23
BDBM85153 CCK-A Agonist 20
BDBM85155 CCK-A Agonist 31
BDBM85156 CCK-A Agonist 41
BDBM85160 CCK-A Agonist 27
BDBM85161 CCK-A Agonist 43
BDBM85162 CCK-A Agonist 44
CCK-A Agonist 15 BDBM85145
CCK-A Agonist 26 BDBM85158
CCK-A Agonist 28 BDBM85144
CCK-A Agonist 37 BDBM85139
CCK-A Agonist 38 BDBM85138
CCK-A Agonist 39 BDBM85159
CCK-A Agonist 40 BDBM85157
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- AT2R AGONIST
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- GLP-1R Agonist and Therapeutic Method Thereof
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- Dack, KN; Johnson, PS; Henriksson, K; Eirefelt, S; Carnerup, MA; Stahlhut, M; Ollerstam, AK Topical 'dual-soft' glucocorticoid receptor agonist for dermatology. Bioorg Med Chem Lett 30: (2020)
- ChEMBL_2304146 Agonist activity at human PPARgamma
- ChEMBL_2493626 Agonist activity at human PPARgamma
- ChEMBL_749292 (CHEMBL1785227) Agonist activity at PPARgamma
- ChEMBL_822294 (CHEMBL2038597) Agonist activity at PPARgamma
- ChEMBL_1458369 (CHEMBL3369562) Agonist activity at human PPARgamma
- ChEMBL_1832094 (CHEMBL4332102) Agonist activity at human PPARgamma
- ChEMBL_2208398 (CHEMBL5121347) Agonist activity at human PPARgamma
- ChEMBL_2281510 Agonist activity at PPARgamma (unknown origin)
- ChEMBL_2304140 Agonist activity at PPARgamma (unknown origin)
- ChEMBL_2346687 Agonist activity at PPARgamma (unknown origin)
- ChEMBL_478518 (CHEMBL922480) Agonist activity at human PPARgamma
- ChEMBL_796445 (CHEMBL1937760) Agonist activity at dog PPARgamma
- ChEMBL_796451 (CHEMBL1937766) Agonist activity at rat PPARgamma
- ChEMBL_796454 (CHEMBL1937769) Agonist activity at mouse PPARgamma
- ChEMBL_1477261 (CHEMBL3428953) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1501099 (CHEMBL3587447) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1506585 (CHEMBL3598338) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1543495 (CHEMBL3750342) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1673159 (CHEMBL4023188) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1795016 (CHEMBL4267133) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1797055 (CHEMBL4269172) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1832152 (CHEMBL4332160) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1843846 (CHEMBL4344273) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1895987 (CHEMBL4398022) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_1989286 (CHEMBL4623021) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_2016851 (CHEMBL4670429) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_2046821 (CHEMBL4701520) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_2160010 (CHEMBL5044760) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_2213999 (CHEMBL5127131) Inverse agonist activity at human PPARgamma
- ChEMBL_2243122 (CHEMBL5157332) Agonist activity at PPARgamma (unknown origin)
- ChEMBL_461488 (CHEMBL927499) Agonist activity at human recombinant PPARgamma
- ChEMBL_1895988 (CHEMBL4398023) Partial agonist activity at PPARgamma (unknown origin)
- ChEMBL_2304144 Agonist activity at PPARgamma in human HepG2 cells
- ChEMBL_380767 (CHEMBL867360) Agonist activity at PPARgamma by transactivation assay
- ChEMBL_633997 (CHEMBL1117970) Agonist activity at Gal4-fused human PPARgamma
- ChEMBL_634000 (CHEMBL1117973) Agonist activity at Gal4-fused mouse PPARgamma
- ChEMBL_1444973 (CHEMBL3371805) Agonist activity at GAL4-tagged PPARgamma (unknown origin)
- ChEMBL_1775436 (CHEMBL4232428) Agonist activity at GAL4-fused human PPARgamma LBD
- ChEMBL_332325 (CHEMBL865192) Agonist activity at PPARgamma transfected in HEK293 cells
- ChEMBL_447649 (CHEMBL896656) Agonist activity at human PPARgamma by transactivation assay
- ChEMBL_455158 (CHEMBL887188) Agonist activity at human PPARgamma by transactivation assay
- ChEMBL_456458 (CHEMBL887279) Agonist activity at human PPARgamma by transactivation assay
- ChEMBL_466292 (CHEMBL950256) Agonist activity at mouse PPARgamma by transactivation assay
- ChEMBL_552431 (CHEMBL1001848) Agonist activity at PPARgamma receptor by cofactor assay
- ChEMBL_627745 (CHEMBL1116167) Agonist activity at PPARgamma assessed as transcriptional activation
- ChEMBL_746399 (CHEMBL1776358) Agonist activity at PPARgamma in mouse 3T3L1 cells
- ChEMBL_153619 (CHEMBL760384) Displacement of PPARgamma agonist from human PPAR gamma receptor
- ChEMBL_2304142 Agonist activity at PPARgamma (unknown origin) assessed as transcriptional activation
- ChEMBL_575838 (CHEMBL1025345) Agonist activity at human PPARgamma by Gal4 transactivation assay
- ChEMBL_630344 (CHEMBL1112866) Agonist activity at human PPARgamma by Gal4 transactivation assay
- ChEMBL_750879 (CHEMBL1786324) Displacement of radio-labeled full agonist from PPARgamma receptor
- ChEMBL_2298063 Partial agonist activity at PPARgamma (unknown origin) in presence of GW1929
- ChEMBL_2300465 Agonist activity at GAL4-fused human PPARgamma expressed in HepG2 cells
- ChEMBL_453571 (CHEMBL885571) Agonist activity at PPARgamma in CV1 cells by transactivation assay
- ChEMBL_456358 (CHEMBL888369) Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay
- ChEMBL_2148792 (CHEMBL5033190) Agonist activity at PPARgamma (unknown origin) assessed as inhibition by agonist-induced corepressor NCoR release assay
- ChEMBL_2298061 Partial agonist activity at PPARgamma (unknown origin) by luciferase reporter gene assay
- ChEMBL_310147 (CHEMBL838126) Agonist activity against human PPARgamma in COS-1 cell Gal4 assay
- ChEMBL_453678 (CHEMBL885679) Agonist activity at PPARgamma in mouse 3T3-L1 cells by IRBA
- ChEMBL_464735 (CHEMBL933081) Agonist activity at PPARgamma in HEK293 cells by GAL4 transactivation assay
- ChEMBL_519279 (CHEMBL947731) Agonist activity at human PPARgamma transactivation expressed in human HePG2 cells
- ChEMBL_544083 (CHEMBL1019543) Agonist activity at human PPARgamma in U2OS cells by transactivation assay
- ChEMBL_562737 (CHEMBL1022409) Agonist activity at human PPARgamma receptor by cell based transactivation assay
- ChEMBL_977422 (CHEMBL2417309) Agonist activity at PPARgamma (unknown origin) by nuclear receptor cofactor assay
- ChEMBL_2242113 (CHEMBL5156323) Agonist activity at human PPARgamma measured by dual luciferase reporter gene assay
- ChEMBL_459988 (CHEMBL944031) Agonist activity at PPARgamma expressed in HEK293 cells by GAL4 transactivation assay
- ChEMBL_468713 (CHEMBL929849) Agonist activity at human PPARgamma expressed in CV1 cells by transactivation assay
- ChEMBL_468721 (CHEMBL930876) Agonist activity at mouse PPARgamma expressed in CV1 cells by transactivation assay
- ChEMBL_514886 (CHEMBL972694) Agonist activity at PPARgamma transfected in HEK293 cells by GAL4 transactivation assay
- ChEMBL_558112 (CHEMBL959041) Agonist activity at human PPARgamma receptor by cell based transient transfection assay
- ChEMBL_558115 (CHEMBL959044) Agonist activity at mouse PPARgamma receptor by cell based transient transfection assay
- ChEMBL_590547 (CHEMBL1059362) Agonist activity at human PPARgamma assessed as luciferase activity by transactivation assay
- ChEMBL_2200545 (CHEMBL5113061) Inverse agonist activity at PPARgamma LBD (unknown origin) assessed as recruitment of corepressor NCOR2 to PPARgamma LBD by LanthaScreen TR-FRET assay
- ChEMBL_2200547 (CHEMBL5113063) Inverse agonist activity at PPARgamma in human RT112/84-FABP4 cells assessed as reduction in PPARgamma transactivation measured by Nanoluciferase reporter gene assay
- ChEMBL_2296038 Partial agonist activity at PPARgamma (unknown origin) by TR-FRET-based competitive binding assay
- ChEMBL_452361 (CHEMBL902600) Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assay
- ChEMBL_454547 (CHEMBL886574) Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assay
- ChEMBL_456953 (CHEMBL924315) Agonist activity at human PPARgamma expressed in NIH3T3 cells by GAL4 transactivation assay
- ChEMBL_459989 (CHEMBL944032) Agonist activity at PPARgamma expressed in HEK293 cells assessed as aP2 gene induction
- ChEMBL_461779 (CHEMBL927785) Agonist activity at human PPARgamma assessed as receptor activation by cell based assay
- ChEMBL_461781 (CHEMBL927787) Agonist activity at mouse PPARgamma assessed as receptor activation by cell based assay
- ChEMBL_466274 (CHEMBL950103) Agonist activity at human PPARgamma expressed in monkey CV1 cells by transactivation assay
- ChEMBL_468345 (CHEMBL931808) Agonist activity at human recombinant PPARgamma in HEK293 cells by GAL4 transactivation assay
- ChEMBL_469931 (CHEMBL938400) Agonist activity at human PPARgamma-Gal4 in HEK293 cells by luciferase reporter assay
- ChEMBL_582389 (CHEMBL1063426) Agonist activity at human PPARgamma expressed in U2OS cells by luciferase transactivation assay
- ChEMBL_718367 (CHEMBL1679899) Agonist activity at human PPARgamma LBD by cell based luciferase reporter gene assay
- ChEMBL_1288935 (CHEMBL3117632) Agonist activity at mouse PPARgamma expressed in CV-1 cells by reporter gene assay
- ChEMBL_1434932 (CHEMBL3385869) Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase reporter gene assay
- ChEMBL_1901925 (CHEMBL4404147) Agonist activity at PPARgamma (unknown origin) incubated for 2 hrs by TR-FRET assay
- ChEMBL_456174 (CHEMBL888184) Agonist activity at human PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assay
- ChEMBL_749314 (CHEMBL1785095) Agonist activity at human PPARgamma in human U2OS cells by cell based transactivation assay
- ChEMBL_757049 (CHEMBL1803890) Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assay
- ChEMBL_884804 (CHEMBL2216558) Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assay
- ChEMBL_940611 (CHEMBL2327553) Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assay
- ChEMBL_2296046 Agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator RAP250 to PPARgamma LBD by TR-FRET-based nuclear receptor coactivator assay
- ChEMBL_1288928 (CHEMBL3117625) Partial agonist activity at mouse PPARgamma expressed in CV-1 cells by reporter gene assay
- ChEMBL_1541240 (CHEMBL3745416) Agonist activity at human PPARgamma assessed as induction of transactivation activity by cell based assay
- ChEMBL_1661181 (CHEMBL4010793) Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells by luciferase reporter gene assay
- ChEMBL_1731512 (CHEMBL4147048) Agonist activity at mouse PPARgamma expressed in 293T cells by dual luciferase reporter gene assay
- ChEMBL_1775426 (CHEMBL4232418) Agonist activity at human PPARgamma after 22 to 24 hrs by luciferase reporter gene assay
- ChEMBL_2339030 Agonist activity at human PPARgamma incubated for 12 hrs by cell based Steady-Glo luciferase assay
- ChEMBL_447438 (CHEMBL896461) Agonist activity at human PPARgamma in CV1 cells by GAL4 transactivation assay after 24 hrs
- ChEMBL_630655 (CHEMBL1111089) Agonist activity against human Gal4-fussed PPARgamma in HEK293 cells by luciferase reporter gene assay
- ChEMBL_748549 (CHEMBL1780402) Agonist activity at Gal4-fussed PPARgamma expressed in human HEK293 cells by reporter gene assay
- ChEMBL_760506 (CHEMBL1815491) Agonist activity at PPARgamma expressed in HEK293 after 8 hrs by luciferase reporter gene assay
- ChEMBL_801285 (CHEMBL1947834) Partial agonist activity at human PPARgamma LBD assessed as activation of PGC1 by HTRF assay
- ChEMBL_801289 (CHEMBL1947838) Partial agonist activity at human PPARgamma LBD assessed as activation of PBP by HTRF assay
- ChEMBL_2244007 (CHEMBL5158217) Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assay
- ChEMBL_566256 (CHEMBL953559) Agonist activity at human PPARgamma ligand binding domain expressed in HEK293 cells by Gal4 transactivation assay
- ChEMBL_584432 (CHEMBL1056703) Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assay
- ChEMBL_610584 (CHEMBL1068976) Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay
- ChEMBL_610592 (CHEMBL1069606) Agonist activity at mouse PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay
- ChEMBL_619894 (CHEMBL1110284) Agonist activity at PPARgamma receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assay
- ChEMBL_626262 (CHEMBL1113509) Agonist activity at human GAL4-tagged PPARgamma chimeric receptor expressed in HEK cells by transactivation assay
- ChEMBL_626931 (CHEMBL1114526) Agonist activity at N-terminal His-tagged human PPARgamma ligand binding domain by fluorescence polarization assay
- ChEMBL_750880 (CHEMBL1786325) Agonist activity at PPARgamma receptor expressed in human HepG2 cells by PPRE-luciferase reporter gene assay
- ChEMBL_800180 (CHEMBL1947742) Agonist activity at human PPARgamma expressed in MG-63 cells by reporter gene-based transactivation assay
- ChEMBL_801283 (CHEMBL1947832) Partial agonist activity at human PPARgamma LBD assessed as activation of CBP1-453 by HTRF assay
- ChEMBL_801287 (CHEMBL1947836) Partial agonist activity at human PPARgamma LBD assessed as activation of Src-1 by HTRF assay
- ChEMBL_955713 (CHEMBL2379023) Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in human HepG2 cells by transactivation assay
- ChEMBL_2170276 (CHEMBL5055335) Partial agonist activity at sGSF-PPARgamma (unknown origin) assessed as CBP-1 recruitment by HT-FRET assay
- ChEMBL_2300464 Agonist activity at human PPARgamma transfected in HEK293 cells assessed increase in luciferase activity incubated for 24 hrs
- ChEMBL_479482 (CHEMBL935698) Agonist activity at human PPARgamma expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assay
- ChEMBL_538924 (CHEMBL1033969) Displacement of fluorescent pan PPAR agonist form GST-tagged human PPARgamma ligand binding domain by FRET assay
- ChEMBL_800179 (CHEMBL1947741) Partial agonist activity at human PPARgamma expressed in MG-63 cells by reporter gene-based transactivation assay
- ChEMBL_801272 (CHEMBL1947821) Agonist activity at human PPARgamma expressed in COS-1 cells co-expressing with Gal4 by transactivation assay
- ChEMBL_464733 (CHEMBL933079) Inhibition of PPARgamma
- ChEMBL_573968 (CHEMBL1062958) Activation of PPARgamma
- ChEMBL_2280261 Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation incubated for 6 to 18 hrs by Nano-Glo luciferase assay
- ChEMBL_1436421 (CHEMBL3390165) Agonist activity at human PPARgamma expressed in HEK293 cells incubated for 18 hrs by luciferase reporter gene assay
- ChEMBL_1460054 (CHEMBL3368588) Agonist activity at human PPARgamma LBD expressed in COS7 cells after 12 hrs by Dual-Glo luciferase assay
- ChEMBL_1508904 (CHEMBL3602054) Agonist activity at human PPARgamma transfected in human MCF7 cells after 16 hrs by luciferase reporter gene assay
- ChEMBL_1807787 (CHEMBL4307146) Agonist activity at PPARgamma (unknown origin) incubated for 3 to 16 hrs by pathhunter nuclear hormone receptor assay
- ChEMBL_502072 (CHEMBL983197) Agonist activity at human PPARgamma expressed in BHK21 cells assessed as SEAP activity by luciferase reporter transactivation assay
- ChEMBL_627234 (CHEMBL1110803) Agonist activity at human PPARgamma LBD (176-477) expressed in HEK293 cells coexpressing GAL4-DBD by transactivation assay
- ChEMBL_1561279 (CHEMBL3778099) Inhibition of human PPARgamma
- ChEMBL_2298071 Transactivation of PPARgamma (unknown origin)
- ChEMBL_2491256 Inhibition of PPARgamma (unknown origin)
- ChEMBL_448678 (CHEMBL897828) Binding affinity to PPARgamma
- ChEMBL_465724 (CHEMBL932290) Binding affinity at PPARgamma
- ChEMBL_627749 (CHEMBL1116171) Binding affinity to PPARgamma
- ChEMBL_834189 (CHEMBL2072929) Binding affinity to PPARgamma
- ChEMBL_1445063 (CHEMBL3372995) Agonist activity at human GAL4-PPARgamma ligand binding domain expressed in human HepG2 cells by luciferase reporter gene assay
- ChEMBL_1463124 (CHEMBL3399107) Agonist activity at GAL4 tagged human PPARgamma ligand binding domain expressed in HEK293 cells by luciferase reporter gene assay
- ChEMBL_2286065 Agonist activity at Gal4-PPARgamma (unknown origin) transfected in HCT-116 cells incubated for 24 hrs by luciferase reporter assay
- ChEMBL_2374213 Agonist activity at PPARgamma (unknown origin) transfected in HEK293 cells incubated for 18 hrs by based dual-glo luciferase assay
- ChEMBL_2502512 Agonist activity at PPARgamma in HEK293 cells assessed as transactivation incubated for 5 to 10 mins by microplate reader analysis
- ChEMBL_643269 (CHEMBL1177258) Agonist activity at human PPARgamma-LBD expressed in COS7 cells co-transfected with Gal4 by luciferase based transactivation assay
- ChEMBL_699546 (CHEMBL1647801) Agonist activity at Gal4-fused human PPARgamma DNA binding domain expressed in HEK293 cells by luciferase reporter gene assay
- ChEMBL_832989 (CHEMBL2067033) Agonist activity at PPARgamma LBD in human 293H DA cells after 16 hrs by TR-FRET activation reporter assay
- ChEMBL_1797042 (CHEMBL4269159) Agonist activity at human GAL4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
- ChEMBL_1901930 (CHEMBL4404152) Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in HEK293T cells incubated for 24 by BrightGlo reagent based assay
- ChEMBL_2332988 Agonist activity at human PPARgamma transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assay
- ChEMBL_512442 (CHEMBL980783) Agonist activity at human PPARgamma receptor expressed in african green monkey COS cells after 48 hrs by GAL4 transactivation assay
- ChEMBL_644947 (CHEMBL1211333) Agonist activity at PPARgamma-LBD expressed in HEK293 cells assessed as Gal4-DBD interaction by cellular mammalian one hybrid assay
- ChEMBL_1515176 (CHEMBL3614523) Inhibition of PPARgamma (unknown origin)
- ChEMBL_1832155 (CHEMBL4332163) Antagonist activity at mouse PPARgamma
- ChEMBL_1895989 (CHEMBL4398024) Transactivation of PPARgamma (unknown origin)
- ChEMBL_1905390 (CHEMBL4407748) Inhibition of PPARgamma (unknown origin)
- ChEMBL_2148831 (CHEMBL5033229) Activity at PPARgamma (unknown origin)
- ChEMBL_2281511 Binding affinity to PPARgamma (unknown origin)
- ChEMBL_2281519 Antagonist activity at PPARgamma (unknown origin)
- ChEMBL_2304156 Binding affinity to PPARgamma (unknown origin)
- ChEMBL_2491257 Antagonist activity at PPARgamma (unknown origin)
- ChEMBL_425041 (CHEMBL910802) Binding affinity to human PPARgamma
- ChEMBL_940548 (CHEMBL2327166) Inhibition of PPARgamma (unknown origin)
- ChEMBL_1706702 (CHEMBL4057935) Displacement of fluormone-PPARgamma green from GST-tagged PPARgamma-LBD (unknown origin) by fluorescence polarization assay
- ChEMBL_1284596 (CHEMBL3106924) Agonist activity at human PPARgamma ligand binding domain expressed in monkey COS7 cells cotransfected with Gal4 by luciferase reporter gene assay
- ChEMBL_1665975 (CHEMBL4015771) Agonist activity at human GAL4 fused PPARgamma-Hinge-LBD expressed in HEK293T cells after 18 hrs by luciferase reporter gene assay
- ChEMBL_1804107 (CHEMBL4276399) Agonist activity at PPARgamma in human MKN45 cells assessed as cell differentiation after 5 days by Hoechst 33342 staining-based assay
- ChEMBL_1893680 (CHEMBL4395601) Agonist activity at GAL4- fused PPARgamma LBD (unknown origin) expressed in African green monkey COS7 cells by luciferase reporter gene assay
- ChEMBL_1977612 (CHEMBL4610747) Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator peptide C33 by TR-FRET assay
- ChEMBL_2123732 (CHEMBL4832965) Agonist activity at human PPARgamma transfected in human HEK293 cells incubated for 18 hrs by Renilla/Firefly dual-luciferase reporter assay
- ChEMBL_2330374 Agonist activity at PPARgamma (unknown origin) transfected in HEK293 cells incubated for 18 hrs by renilla/firefly based dual-glo luciferase assay
- ChEMBL_2461134 Agonist activity at human PPARgamma transfected in african green monkey COS7 cells assessed transcriptional activation incubated for 24 hrs by luciferase assay
- ChEBML_1636654 Displacement of fluormone-PPARgamma Green from recombinant human N-terminal GST-tagged PPARgamma-LBD by fluorescence polarization assay
- ChEMBL_1364076 (CHEMBL3292015) Antagonist activity at PPARgamma (unknown origin)
- ChEMBL_1832149 (CHEMBL4332157) Antagonist activity at PPARgamma (unknown origin)
- ChEMBL_375289 (CHEMBL865405) Transactivation of PPARgamma in CV1 cells
- ChEMBL_912978 (CHEMBL3057027) Transactivation activity at PPARgamma (unknown origin)
- ChEMBL_1665977 (CHEMBL4015773) Agonist activity at human PPARgamma LBD expressed in HEK293 cells assessed as coactivator DRIP205 protein recruitment after 18 hrs by HTRF assay
- ChEMBL_1742220 (CHEMBL4157970) Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay
- ChEMBL_1742341 (CHEMBL4158091) Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay
- ChEMBL_1785242 (CHEMBL4256759) Partial agonist activity at human PPARgamma LBD expressed HEK293T cells after 12 to 14 hrs by dual-glo luciferase reporter gene assay
- ChEMBL_1927659 (CHEMBL4430731) Agonist activity at N-terminal Gal4 fused human PPARgamma LBD transfected in HEK293 cells after 24 hrs by luciferase reporter gene assay
- ChEMBL_2051752 (CHEMBL4706451) Agonist activity at PPARgamma LBD (unknown origin) assessed as increase in recruitment of coactivator peptide fluorescein-TRAP220/DRIP by TR-FRET assay
- ChEMBL_2154911 (CHEMBL5039571) Partial agonist activity at Gal4-fused human PPARgamma LBD in HepG2 cells assessed as transactivation incubated for 20 hrs measured by luminometer
- ChEMBL_2185288 (CHEMBL5097370) Agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HepG2 cells incubated for 18 hrs by dual luciferase reporter assay
- ChEMBL_2200565 (CHEMBL5113081) Inverse agonist activity at GAL4-tagged mouse PPARgamma LBD expressed in CHO cells measured after 6 hrs by firefly luciferase reporter assay
- ChEMBL_2200567 (CHEMBL5113083) Inverse agonist activity at GAL4-tagged human PPARgamma LBD expressed in CHO cells measured after 6 hrs by firefly luciferase reporter assay
- ChEMBL_2208320 (CHEMBL5121269) Agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled PRIP/RAP250 coactivator peptide requirement by Lanthascreen TR-FRET assay
- ChEMBL_2216501 (CHEMBL5129633) Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in FITC-labeled PGC-1alpha coactivator peptide recruitment by HTRF assay
- ChEMBL_492848 (CHEMBL941195) Agonist activity at human PPARgamma ligand binding domain expressed in human HepG2 cells co-transfected with Gal4 by luciferase reporter gene assay
- ChEMBL_513558 (CHEMBL979054) Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to control
- ChEMBL_616573 (CHEMBL1099710) Agonist activity at human recombinant PPARgamma LBD expressed in african green monkey COS7 cells coexpressing GAL4 by luciferase reporter gene transactivation assay
- ChEMBL_620647 (CHEMBL1114855) Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation assay
- ChEMBL_627245 (CHEMBL1111743) Agonist activity at full length human PPARgamma expressed in HepG2 cells co-transfected with pBL-tk-luciferase by luciferase reporter gene assay
- ChEMBL_698586 (CHEMBL1647859) Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assay
- ChEMBL_747912 (CHEMBL1781231) Agonist activity at human PPARgamma-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assay
- ChEBML_1716407 Inhibition of fluormone PPARgamma Green binding to recombinant N-terminal GST-tagged human PPARgamma LBD by fluorescence polarization assay
- ChEMBL_1506465 (CHEMBL3599864) Displacement of fluormone PPARgamma green from GST-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assay
- ChEMBL_1636654 (CHEMBL3879552) Displacement of fluormone-PPARgamma Green from recombinant human N-terminal GST-tagged PPARgamma-LBD by fluorescence polarization assay
- ChEBML_1620635 Agonist activity at GAL4-tagged human PPARgamma ligand binding domain chimeric receptor expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay
- ChEMBL_1453700 (CHEMBL3364102) Agonist activity at mouse PPARgamma expressed in HEK293 cells co-expressing with Gal4 reporter vector after 24 hrs by dual-luciferase reporter assay
- ChEMBL_1501861 (CHEMBL3588048) Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay
- ChEMBL_1776595 (CHEMBL4233587) Agonist activity at PPARgamma in human HepG2 cells assessed as activation of PPRE incubated for 24 hrs by dual luciferase reporter gene assay
- ChEMBL_2103700 (CHEMBL4812203) Agonist activity at human Gal4 fused PPARgamma LBD expressed in COS-7 cells incubated for 24 hrs by firefly luciferase reporter gene assay
- ChEMBL_2148292 (CHEMBL5032690) Agonist activity at human PPARgamma transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactivation assay
- ChEMBL_2208319 (CHEMBL5121268) Agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled TRAP220/DRIP-2 coactivator peptide requirement by Lanthascreen TR-FRET assay
- ChEMBL_2218662 (CHEMBL5131996) Inverse agonist activity at His6-tagged PPARgamma LBD (unknown origin) assessed as N-terminal biotinylated PGC1a coactivator peptide recruitment by TR-FRET assay
- ChEMBL_2263415 (CHEMBL5218426) Partial agonist activity at PPARgamma (unknown origin) assessed as increase in fluorescein labeled PRIP/RAP250 coactivator peptide requirement by Lanthascreen TR-FRET assay
- ChEMBL_572393 (CHEMBL1035294) Agonist activity at human PPARgamma receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation assay
- ChEMBL_642072 (CHEMBL1176104) Partial agonist activity at rat PPARgamma-LBD expressed in CHO-K1 cells co-transfected with GAL4 assessed as luciferase activity by transactivation assay
- ChEMBL_642076 (CHEMBL1176108) Partial agonist activity at human PPARgamma-LBD expressed in CHO-K1 cells co-transfected with GAL4 assessed as luciferase activity by transactivation assay
- ChEMBL_642079 (CHEMBL1176273) Partial agonist activity at mouse PPARgamma-LBD expressed in CHO-K1 cells co-transfected with GAL4 assessed as luciferase activity by transactivation assay
- ChEMBL_754671 (CHEMBL1805526) Agonist activity at PPARgamma expressed in HepG2 cells co-expressing PPRE assessed as transcriptional activation after 24 hrs by luciferase reporter gene assay
- ChEMBL_792687 (CHEMBL1930423) Agonist activity at human PPARgamma ligand binding domain expressed in COS-1 cells after 24 hrs by luciferase reporter gene-based luminometric analysis
- ChEMBL_880126 (CHEMBL2214362) Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivation assay
- ChEMBL_944086 (CHEMBL2341919) Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase reporter gene assay
- ChEMBL_2280259 Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of fluorescein labeled corepressor NCOR2 Smrt-ID2 peptide to PPARgamma LBD incubated for 24 hrs by LanthaScreen TR-FRET assay
- ChEMBL_304584 (CHEMBL828475) In vitro binding affinity against human PPARgamma
- ChEMBL_425031 (CHEMBL912552) Activity at human PPARgamma in CV1 cells
- ChEMBL_462571 (CHEMBL928497) Displacement of [3H]Rosiglitazone from human PPARgamma
- ChEMBL_627747 (CHEMBL1116169) Inhibition of PPARgamma assessed as transcriptional activity
- ChEMBL_912979 (CHEMBL3057028) Transactivation activity at Homo sapiens (human) PPARgamma
- ChEBML_1672306 Agonist activity at GAL4N fused human PPARgamma LBD expressed in HEK293 cells co-expressing TK-MH100x4-Luc after 24 hrs by luciferase reporter gene assay
- ChEMBL_1477131 (CHEMBL3428440) Agonist activity at PPARgamma ligand binding domain (unknown origin) using fluormone Pan-PPAR green tracer by TR-FRET assay based competitive ligand binding method
- ChEMBL_1672313 (CHEMBL4022342) Agonist activity at GAL4 fused human PPARgamma LBD (174 to 475 residues) expressed in HEK293T cells after 18 hrs by luciferase reporter gene assay
- ChEMBL_1858614 (CHEMBL4359343) Partial agonist activity at Gal4-fused PPARgamma LBD (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assay
- ChEMBL_1931086 (CHEMBL4434337) Agonist activity at PPARgamma (unknown origin) assessed as receptor transactivation after 24 hrs by TK-PPRE-Luc expressing cells based luciferase reporter gene assay
- ChEMBL_2013170 (CHEMBL4666748) Agonist activity at human Gal4-DBD fused PPARgamma LBD (unknown origin) expressed in COS-7 cells incubated for 24 hrs by firefly luciferase assay
- ChEMBL_2016850 (CHEMBL4670428) Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene assay
- ChEMBL_2170255 (CHEMBL5055314) Partial agonist activity at GAL4-tagged human PPARgamma LBD expressed in HEK293T cells incubated for 12 to 14 hrs by dual-Glo luciferase assay
- ChEMBL_2243610 (CHEMBL5157820) Agonist activity at pBIND tagged human PPARgamma expressed in human HEK293 cells incubated for 18 hrs by dual luciferase reporter assay relative to control
- ChEMBL_506977 (CHEMBL938813) Agonist activity at human PPARgamma expressed in mouse NIH/3T3 cells assessed as receptor activation after 16 hrs by luciferase based reporter gene assay
- ChEMBL_509887 (CHEMBL998732) Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by luciferase reporter assay
- ChEMBL_535521 (CHEMBL986147) Agonist activity at human PPARgamma expressed in african green monkey CV-1 co-transfected with GAL4 by by dual-glo luciferase reporter gene assay
- ChEMBL_539582 (CHEMBL1035757) Agonist activity at human PPARgamma ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transactivation assay
- ChEMBL_544072 (CHEMBL1019532) Agonist activity at human PPARgamma expressed in african green monkey CV1 cells co-transfected with Gal4 assessed as reporter activity by transient transactivation assay
- ChEMBL_591832 (CHEMBL1042381) Agonist activity at GAL4-tagged human PPARgamma ligand binding domain expressed in human HepG2 cells assessed as receptor transactivation by luciferase reporter gene assay
- ChEMBL_740347 (CHEMBL1764348) Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by transactivation assay
- ChEBML_1672311 Agonist activity at 3' GAL4 DNA binding domain fused mouse PPARgamma LBD expressed in U-2 OS cells after 40 hrs by luciferase reporter gene assay
- ChEMBL_1672306 (CHEMBL4022335) Agonist activity at GAL4N fused human PPARgamma LBD expressed in HEK293 cells co-expressing TK-MH100x4-Luc after 24 hrs by luciferase reporter gene assay
- ChEMBL_2060113 (CHEMBL4715114) Agonist activity at full-length PPARgamma (unknown origin) expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dual-Glo luciferase assay
- ChEMBL_2104549 (CHEMBL4813052) Agonist activity at Gal4-fused human PPARgamma expressed in monkey CV1 cells assessed as receptor transactivation incubated for 45 hrs by luciferase reporter gene assay
- ChEMBL_520073 (CHEMBL940694) Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by luciferase reporter gene assay
- ChEMBL_696727 (CHEMBL1638639) Partial agonist activity at human PPARgamma-LBD expressed in HEK293T cells assessed as induction of receptor transactivation after 24 hrs by luciferase reporter gene assay
- ChEMBL_885704 (CHEMBL2212305) Agonist activity at PPARgamma-LBD expressed in human L02 cells co-expressing pGL3-SV40-GAL4 after 24 hrs by luciferase reporter gene based transactivation assay
- ChEMBL_1927649 (CHEMBL4430721) Displacement of [3H]rosiglitazone from PPARgamma (unknown origin)
- ChEMBL_352521 (CHEMBL860010) Displacement of [3H]rosiglitazone from PPARgamma by SPA
- ChEMBL_355605 (CHEMBL853176) Effect on human PPARgamma transactivation in 293T cells
- ChEMBL_437001 (CHEMBL886017) Effect on PPARgamma transactivation activity in HEK293 cells
- ChEMBL_566255 (CHEMBL953558) Binding affinity to PPARgamma by fluorescence polarization assay
- ChEMBL_575837 (CHEMBL1025344) Displacement of [3H]rosiglitazone from human PPARgamma receptor
- ChEMBL_718347 (CHEMBL1679767) Binding affinity to PPARgamma by fluorescence polarization assay
- ChEMBL_1756927 (CHEMBL4191935) Agonist activity at GAL4-fused PPARgamma LBD (unknown origin) expressed in HEK293 cells assessed as receptor transactivation after 18 hrs by dual luciferase reporter gene assay
- ChEMBL_2100239 (CHEMBL4808635) Agonist activity at human PPARgamma expressed in CHO cells assessed as increase in receptor transcriptional activity incubated for 24 hrs by dual luciferase reporter gene assay
- ChEMBL_2170278 (CHEMBL5055337) Partial agonist activity at recombinant sGSF-PPARgamma (unknown origin) assessed as reduction in rosiglitazone induced CBP-1 recruitment incubated for 1 hr by HTRF competitive assay
- ChEMBL_2216509 (CHEMBL5129641) Partial agonist activity at PPARgamma LBD (unknown origin) assessed as increase in FITC-labeled PGC-1alpha coactivator peptide recruitment in presence of GW9662 by HTRF assay
- ChEMBL_2269557 Agonist activity at PPARgamma in human BMMSC cells assessed as promotion of adiponectin secretion by measuring increase in adiponectin level in presence of IDX medium by ELISA
- ChEMBL_2300218 Agonist activity at GST fused PPARgamma (unknown origin) expressed in Escherichia coli DH5alpha in presence of [3H]BRL49653 incubated for 2 hrs by liquid scintillation counter analysis
- ChEMBL_805974 (CHEMBL1960410) Agonist activity at GAL4-tagged human PPARgamma ligand binding domain expressed in HepG2 cells assessed as transactivation after 20 hrs by beta-galactosidase reporter gene assay
- ChEMBL_1456191 (CHEMBL3361946) Binding affinity to human PPARgamma by SPA/Abse5 assay
- ChEMBL_2165873 (CHEMBL5050734) Inhibition of PPARgamma (unknown origin) phosphorylation at pS273 residue
- ChEMBL_2277703 Binding affinity to PPARgamma (unknown origin) by competitive binding assay
- ChEMBL_304362 (CHEMBL840102) Effective concentration against human PPARgamma expressed in HepG2 cells
- ChEMBL_389968 (CHEMBL868631) Binding affinity to PPARgamma by radio ligand binding assay
- ChEMBL_556513 (CHEMBL956508) Displacement of [3H]rosigliatzone from PPARgamma in rat adipocytes
- ChEMBL_572391 (CHEMBL1035292) Inhibition of human PPARgamma receptor by scintillation proximity assay
- ChEMBL_610660 (CHEMBL1071680) Inhibition of human PPARgamma receptor by ligand displacement assay
- ChEMBL_796384 (CHEMBL1937699) Transactivation of human PPARgamma expressed in CHO-K1 cells
- ChEMBL_801271 (CHEMBL1947820) Binding affinity to human PPARgamma by scintillation proximity assay
- ChEMBL_1809453 (CHEMBL4308812) Agonist activity at PPARgamma in human MKN45 cells assessed as induction of cell aggregation incubated for 5 days by Hoechst 33342 staining based IN cell analyzer method
- ChEMBL_1840162 (CHEMBL4340377) Agonist activity at human PPARgamma expressed in African green monkey COS7 cells assessed as increase in receptor transcriptional activity by luciferase reporter gene assay relative to rosiglitazone
- ChEMBL_2149040 (CHEMBL5033438) Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by dual-Glo luciferase assay
- ChEMBL_2218661 (CHEMBL5131995) Inverse agonist activity at His6-tagged PPARgamma LBD (unknown origin) assessed as N-terminal biotinylated PGC1a coactivator peptide recruitment in presence of rosiglitazone by TR-FRET assay
- ChEMBL_2248188 (CHEMBL5162398) Agonist activity at yeast Gal4-fused human PPARgamma transfected in human HepG2 cells assessed as transactivation by measuring beta-galactosidase activity incubated for 20 hrs by luminometry
- ChEMBL_2269578 Partial agonist activity at PPARgamma in human BMMSC cells assessed as promotion of adiponectin secretion by measuring increase in adiponectin level in presence of IDX medium by ELISA
- ChEMBL_948911 (CHEMBL2341205) Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
- ChEMBL_1844145 (CHEMBL4344572) Agonist activity at human PPARgamma expressed in nonhuman mammalian cells assessed as increase in receptor transcriptional activity incubated for 22 to 24 hrs by luciferase reporter gene assay
- ChEMBL_1858625 (CHEMBL4359354) Partial agonist activity at recombinant N-terminal GFP-fused PPARgamma LBD (unknown origin) assessed as increase in biotinylated-CBP peptide recruitment measured after 2 hrs by HTRF assay
- ChEMBL_1858626 (CHEMBL4359355) Partial agonist activity at recombinant N-terminal GFP-fused PPARgamma LBD (unknown origin) assessed as increase in biotinylated-SRC1 peptide recruitment measured after 2 hrs by HTRF assay
- ChEMBL_2066568 (CHEMBL4721821) Agonist activity at recombinant human PPARgamma LBD (205 to 505 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by luciferase reporter gene assay
- ChEMBL_2472175 Agonist activity at GAL4-tagged human PPARgamma transfected in African green monkey COS7 cells assessed as transcriptional activation by measuring effective concentration incubated for 24 hrs by luciferase assay
- ChEMBL_2484584 Partial agonist activity at N-terminal Gal4-fused human PPARgamma LBD transfected in human HepG2 cells assessed as receptor transactivation incubated for 20 hrs by luciferase based luminometric assay
- ChEMBL_806234 (CHEMBL1958775) Agonist activity at human PPARgamma expressed in CHO cells co-transfected with pGL3-PPRE3-TK-luc assessed as transactivation after 24 hrs by firefly luciferase reporter gene assay
- ChEMBL_1456192 (CHEMBL3361947) Binding affinity to human PPARgamma by SPA/summary (Abse5) assay
- ChEMBL_1834023 (CHEMBL4334031) Binding affinity to PPARgamma (unknown origin) by TR-FRET assay
- ChEMBL_2014076 (CHEMBL4667654) Binding affinity to PPARgamma (unknown origin) by TR-FRET assay
- ChEMBL_2374957 Displacement of [3H ]rosiglitazone from human PPARgamma by radioligand binding assay
- ChEMBL_438927 (CHEMBL889270) Activity at human PPARgamma receptor by cell based transactivation assay
- ChEMBL_438960 (CHEMBL889304) Displacement of [3H]BRL49653 from PPARgamma by scintillation proximity assay
- ChEMBL_635648 (CHEMBL1119540) Transactivation of PPARgamma assessed as induction of alkaline phosphatase activity
- ChEMBL_795138 (CHEMBL1936610) Displacement of [3H]-AD-5061 from human GST-tagged PPARgamma
- ChEMBL_815395 (CHEMBL2027047) Displacement of [3H]-AD-5061 from human GST-tagged PPARgamma
- ChEMBL_1984719 (CHEMBL4618125) Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6 hrs by dual luciferase reporter gene assay
- ChEMBL_2280278 Inverse agonist activity at human PPARgamma expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional repression preincubated for 6 hrs followed by luciferin addition by luminescence method
- ChEMBL_2300221 Agonist activity at yeast GAL4-fused human PPARgamma expressed in human HepG2 cells co-expressing pFR-Luc assessed as luciferase activity incubated for 48 hrs by Luciferase reporter gene Assay
- ChEMBL_496540 (CHEMBL996817) Agonist activity at human PPARgamma ligand binding domain expressed in human HepG2 cells co-transfected with PPRE3-TK-luc assessed as induction of beta-galactosidase activity by transactivation assay
- ChEMBL_608118 (CHEMBL1074807) Agonist activity at human full length PPARgamma expressed in human HepG2 cells co-transfected with PPRE3-TK-luc assessed as induction of beta-galactosidase activity by firefly luciferase assay
- ChEMBL_2280298 Inverse agonist activity at PPARgamma in mouse 3T3-L1 adipocytes assessed as inhibition of adipogenesis by measuring lipid droplet staining by BODIPY 495 incubated for 6 days by fluorescence based assay
- ChEMBL_565041 (CHEMBL959184) Agonist activity at PPARgamma ligand binding domain expressed in human HeLa cells co-transfected with Gal4-DBD assessed as transcriptional activation by Gal4 response element-driven luciferase reporter gene assay
- ChEMBL_700724 (CHEMBL1645939) Agonist activity at human PPARgamma expressed in HepG2 cells co-transfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 hrs by luciferase based transactivation assay
- ChEMBL_1458370 (CHEMBL3369563) Binding affinity to human His-tagged PPARgamma LBD by SPR method
- ChEMBL_1565229 (CHEMBL3782623) Competitive binding affinity to PPARgamma (unknown origin) by TR-FRET assay
- ChEMBL_1911903 (CHEMBL4414349) Binding affinity to recombinant PPARgamma (unknown origin) by isothermal titration calorimetry
- ChEMBL_2165848 (CHEMBL5050709) Binding affinity to PPARgamma (unknown origin) by lanthascreen TR-FRET assay
- ChEMBL_425010 (CHEMBL912531) Displacement of tritium labeled ligand from human PPARgamma by SPA assay
- ChEMBL_819639 (CHEMBL2033824) Binding affinity to GST-tagged human PPARgamma by TR-FRET analysis
- ChEMBL_880132 (CHEMBL2214368) Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetry
- ChEMBL_1462847 (CHEMBL3399721) Agonist activity at GAL4-DNA binding domain fused human PPARgamma ligand binding domain expressed in human HepG2 cells assessed as receptor transactivation incubated for 20 hrs by luciferase reporter gene assay
- ChEMBL_1894780 (CHEMBL4396701) Agonist activity at full length human FLAG-tagged GAL4-DBD fused PPARgamma LBD (205 to 505 residues) expressed in COS1 cells measured after 18 hrs by dual luciferase reporter gene assay
- ChEMBL_2085052 (CHEMBL4766315) Agonist activity at human CMV-fused PPARgamma LBD/RXRalpha (unknown origin) expressed in African green monkey CV1 cells transfected with luciferase plasmid measured after 24 hrs by luciferase reporter gene assay
- ChEMBL_2160026 (CHEMBL5044776) Agonist activity at mouse PPARgamma in Cos7 cells transfected with pBIND and pGL4.35 Gal4 UAS Luc reporter plasmid by measuring luciferase activity incubated for 16 hrs by luciferase reporter gene assay
- ChEMBL_2165849 (CHEMBL5050710) Agonist activity at Gal4-fused PPARgamma (unknown origin) expressed in human U2OS cells co-transfected with pSG5 expression vector preincubated for 40 hrs followed by substrate addition by microplate reader assay
- ChEMBL_820376 (CHEMBL2037719) Agonist activity at human recombinant PPARgamma expressed in CHO cells cotransfected with pGL3-PPRE3-TK-luc reporter assessed as beta-galactosidase activity at after 24 hrs by luciferase based transactivation assay
- ChEMBL_901085 (CHEMBL3062690) Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after 4 days by insulin receptor binding assay
- ChEMBL_1832100 (CHEMBL4332108) Binding affinity to PPARgamma (unknown origin) by TR-FRET competitive binding assay
- ChEMBL_1995679 (CHEMBL4629574) Binding affinity to recombinant PPARgamma LBD (unknown origin) by isothermal titration calorimetry
- ChEMBL_2296037 Binding affinity to PPARgamma (unknown origin) by TR-FRET-based competitive binding assay
- ChEMBL_389972 (CHEMBL868635) Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazone
- ChEMBL_393997 (CHEMBL854666) Activity at PPARgamma by luciferase reporter gene transactivation assay in COS7 cells
- ChEMBL_396485 (CHEMBL911539) Transactivation of human PPARgamma in CV1 cells by luciferase reporter gene assay
- ChEMBL_438961 (CHEMBL889303) Transactivation of human PPARgamma in CV-1 cells by GAL4 reporter assay
- ChEMBL_454546 (CHEMBL886573) Displacement of fluorescein labeled ligand from PPARgamma receptor by fluorescence polarization assay
- ChEMBL_460036 (CHEMBL943155) Displacement of [3H]rosiglitazone from human PPARgamma receptor by scintillation proximity assay
- ChEMBL_496449 (CHEMBL1004580) Displacement of [3H]rosiglitazone from mouse PPARgamma receptor by scintillation proximation assay
- ChEMBL_741373 (CHEMBL1764899) Displacement of [3H]GW 2433 from human PPARgamma by scintillation proximity assay
- ChEMBL_832987 (CHEMBL2067031) Binding affinity to PPARgamma LBD by fluorescence polarization based competitive binding assay
- ChEMBL_944087 (CHEMBL2341920) Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assay
- ChEMBL_970845 (CHEMBL2406696) Binding affinity to GST-tagged human PPARgamma LBD by ligand displacement assay
- ChEMBL_1779840 (CHEMBL4236832) Synergistic agonist activity at human PPARgamma LBD assessed as biotin-labeled PGC1alpha (130 to 154 residues) co-activator recruitment after 1 hr in presence of 0.37 uM rosiglitazone by TR-FRET assay
- ChEMBL_1779841 (CHEMBL4236833) Synergistic agonist activity at human PPARgamma LBD assessed as biotin-labeled PGC1alpha (130 to 154 residues) co-activator recruitment after 1 hr in presence of 1 uM rosiglitazone by TR-FRET assay
- ChEMBL_1779842 (CHEMBL4236834) Synergistic agonist activity at human PPARgamma LBD assessed as biotin-labeled PGC1alpha (130 to 154 residues) co-activator recruitment after 1 hr in presence of 10 uM rosiglitazone by TR-FRET assay
- ChEMBL_1878653 (CHEMBL4380047) Inverse agonist activity at His6-tagged PPARgamma LBD (unknown origin) assessed as inhibition of rosiglitazone-induced N-terminal biotinylated co-activator SRC1 box2 peptide recruitment measured after 30 mins by TR-FRET assay
- ChEMBL_2117957 (CHEMBL4827023) Partial agonist activity at GAL4 DBD-fused PPARgamma LBD (unknown origin) expressed in pG5 luc and pBIND transfected HEK293T cells assessed as transcriptional activation incubated for 12 hrs by fluorescence based luciferase assay
- ChEMBL_2160023 (CHEMBL5044773) Agonist activity at human PPARgamma transfected in Cos7 cells co-expressing with pBIND and pGL4.35 Gal4 UAS Luc reporter plasmid by measuring luciferase activity incubated for 16 hrs by luciferase reporter gene assay
- ChEMBL_1501030 (CHEMBL3587211) Activity at PPARgamma (unknown origin) assessed as transactivation activity by reporter gene assay
- ChEMBL_1559784 (CHEMBL3779737) Displacement of [3H]rosiglitazone from human recombinant PPARgamma receptor expressed in Escherichia coli
- ChEMBL_496803 (CHEMBL1008816) Displacement of [3H]BRL49653 from PPARgamma ligand binding domain by scintillation proximity assay
- ChEMBL_529095 (CHEMBL971112) Activation of PPARgamma transfected in human MCF7 cells by luciferase reporter gene assay
- ChEMBL_106050 (CHEMBL718216) Agonist potency against cloned Metabotropic glutamate receptor 2 agonist
- ChEMBL_1867731 (CHEMBL4368706) Antagonist actvity in pFA-GAL4-DBD fused PPARgamma LBD (unknown origin) transfected in HEK293T cells assessed as inhibition of rosiglitazone-induced PPARgamma transactivation incubated for 24 hrs by luciferase reporter gene assay
- ChEMBL_2157890 (CHEMBL5042640) Agonist activity at human GAL4 DBD-fused PPARgamma LBD (203 to 505 residues) transfected in HEK293T cells assessed as fold activation incubated for 14 to 16 hrs by Renilla/Firefly dual-luciferase reporter assay
- ChEMBL_2357055 Agonist activity at PPAR gamma in GeneBLAzer PPARgamma-UAS-bla HEK 293H cells preincubated with compound for 16 to 24 hrs followed by substrate addition and measured after 2 hrs by fluorescence plate reader analysis
- ChEMBL_2373842 Agonist activity at human PPARgamma-LBD transfected in HEK293T cells co-transfected with pFR-Luc/pRL-SV40 assessed as transfection efficiency by measuring luciferase activity measured after 16 hrs by Gal4 hybrid reporter gene assay
- ChEMBL_2422439 Agonist activity at human PPARgamma transfected in African green monkey COS-7 cells co-transfected with pGL4.35 and pBIND reporter gene plasmid assessed as receptor transactivation incubated for 16 hrs by luciferase reporter gene assay
- ChEMBL_1995677 (CHEMBL4629572) Agonist activity at recombinant human pFA-CMV fused PPARgamma expressed in HEK293T cells transfected with pFR-luciferase plasmid and pRL-SV40 plasmid incubated for 14 to 16 hrs by dual glo luciferase reporter gene assay
- ChEMBL_1658515 (CHEMBL4008127) Binding affinity to PPARgamma (unknown origin) assessed as thermodynamic dissociation constant by SPR assay
- ChEMBL_1658550 (CHEMBL4008162) Binding affinity to PPARgamma (unknown origin) assessed as kinetic dissociation constant by SPR assay
- ChEMBL_2212709 (CHEMBL5125658) Binding affinity to PPARgamma (unknown origin) by TR-FRET based LanthaScreen competitive binding assay
- ChEMBL_573966 (CHEMBL1062956) Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assay
- ChEMBL_832988 (CHEMBL2067032) Displacement of pan-PPAR fluormone from PPARgamma LBD by TR-FRET based LanthaScreen assay
- ChEMBL_899662 (CHEMBL3052673) Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assay
- ChEMBL_933250 (CHEMBL3069174) Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay
- ChEMBL_1867743 (CHEMBL4368718) Antagonist actvity in sGFP-tagged PPARgamma LBD (unknown origin) assessed as inhibition of rosiglitazone-induced PPARgamma activation incubated for 1 hr in presence of CBP-1 cofactor peptide by HTRF based cofactor recruitment assay
- ChEBML_1669056 Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARgamma LBD by TR-FRET assay
- ChEMBL_1539559 (CHEMBL3738480) Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assay
- ChEMBL_1665979 (CHEMBL4015775) Displacement of [3H]rosiglitazone from human PPARgamma LBD expressed in HEK293 cells by filtration assay
- ChEMBL_1824732 (CHEMBL4324496) Inhibition of Gal4-tagged PPARgamma LBD (unknown origin) by cell based luciferase reporter gene assay
- ChEMBL_2220574 (CHEMBL5133908) Transactivation of Gal4-fused human PPARgamma expressed in CHO cells co expressing pG5-Luc reporter
- ChEMBL_2263411 (CHEMBL5218422) Binding affinity to PPARgamma (unknown origin) assessed as inhibition constant by Cheng-Prusoff equation analysis
- ChEMBL_460035 (CHEMBL943154) Antagonist activity at human PPARgamma receptor assessed as rosiglitazone-induced receptor activation by alphascreen assay
- ChEMBL_649482 (CHEMBL1219180) Activation of Gal4-tagged human PPARgamma expressed in CHO cells by luciferase reporter gene assay
- ChEMBL_2318527 Agonist activity at human PPARgamma (182 to 505 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed as receptor transactivation incubated for 24 to 28 hrs by luciferase reporter gene assay
- ChEMBL_2318535 Agonist activity at mouse PPARgamma (182 to 505 residues) expressed in CHO-K1 cells co-transfected with GAL4 and pGluc reporter gene plasmid assessed as receptor transactivation incubated for 24 to 28 hrs by luciferase reporter gene assay
- ChEMBL_104254 (CHEMBL714372) Agonist activity of compound towards mouse Melanocortin-4 receptor (mMC4R); partial agonist
- ChEMBL_106849 (CHEMBL714836) Agonist activity of compound towards mouse Melanocortin-3 receptor (mMC3R); partial agonist
- ChEMBL_939270 (CHEMBL2327067) Agonist activity at RXR (unknown origin) in presence of RAR agonist Am80
- ChEMBL_1455687 (CHEMBL3366032) Activation of human PPARgamma ligand binding domain expressed in COS7 cells by luciferase reporter gene assay
- ChEMBL_1728955 (CHEMBL4144233) Transactivation of human PPARgamma expressed in CHO cells after 24 hrs by luciferase reporter gene assay
- ChEMBL_1753306 (CHEMBL4188066) Displacement of fluormone Pan-PPAR Green from human GST-tagged PPARgamma-LBD by TR-FRET assay
- ChEMBL_2020972 (CHEMBL4674785) Binding affinity to human recombinant PPARgamma by Cheng-Prusoff equation based competitive binding TR-FRET assay
- ChEMBL_438962 (CHEMBL889305) Inhibition of BRL-49653 stimulated human PPARgamma transactivation in CV-1 cells by GAL4 reporter assay
- ChEMBL_512441 (CHEMBL980782) Displacement of [3H]2AD-5075 from GST-tagged human PPARgamma receptor expressed in Escherichia coli BL21
- ChEMBL_812494 (CHEMBL2014330) Transactivation of GAL4-fused PPARgamma LBD expressed in HepG2 cells after 20 hrs by luminescence assay
- ChEMBL_819633 (CHEMBL2033818) Transactivation of human PPARgamma expressed in african green monkey CV1 cells by luciferase reporter gene assay
- ChEMBL_859760 (CHEMBL2169400) Inhibition of fluormone binding to human PPARgamma LBD after 2 hrs by competitive fluorescence polarization assay
- ChEMBL_1898203 (CHEMBL4400238) Antagonist activity at human PPARgamma LBD expressed in yeast AH109 cells assessed as reduction in rosiglitazone-stimulated PPARgamma/CBP interaction by measuring alpha galactosidase activity using PNP-alpha-Gal as substrate by alpha-galactosidase based yeast-two hybrid assay
- ChEBML_153709 Agonist activity against PPAR alpha
- ChEBML_154534 Agonist activity against PPAR gamma
- ChEBML_154542 Agonist activity against PPAR delta
- ChEBML_1682489 Agonist activity at human TGR5
- ChEBML_1682491 Agonist activity at mouse TGR5
- ChEBML_1684415 Agonist activity at mouse GPR52
- ChEMBL_2267947 Agonist activity at human TLR7
- ChEMBL_2268534 Agonist activity at human FXR
- ChEMBL_2273235 Agonist activity at human TAAR1
- ChEMBL_2274190 Agonist activity at human TLR8
- ChEMBL_2275379 Agonist activity at human D4R
- ChEMBL_2276094 Agonist activity at human FXR
- ChEMBL_2281197 Agonist activity at mouse STING
- ChEMBL_2287251 Agonist activity at mouse TGR5
- ChEMBL_2287252 Agonist activity at human TGR5
- ChEMBL_2296943 Agonist activity at human P2Y1
- ChEMBL_2296961 Agonist activity at human P2Y2
- ChEMBL_2303321 Agonist activity at human RORgammat
- ChEMBL_2304136 Agonist activity at mouse PPARalpha
- ChEMBL_2304137 Agonist activity at human PPARalpha
- ChEMBL_2304145 Agonist activity at human PPARdelta
- ChEMBL_2331723 Agonist activity at human TLR3
- ChEMBL_2331724 Agonist activity at human TLR8
- ChEMBL_2331725 Agonist activity at human TLR9
- ChEMBL_2331741 Agonist activity at human TLR7
- ChEMBL_2349299 Agonist activity at human TLR8
- ChEMBL_2349325 Agonist activity at mouse TLR7
- ChEMBL_2349468 Agonist activity at mouse TLR7
- ChEMBL_2349473 Agonist activity at human TLR8
- ChEMBL_2376399 Agonist activity at human FXR
- ChEMBL_2443909 Agonist activity at mouse FPR2
- ChEMBL_452234 (CHEMBL901386) Agonist activity at GHSR
- ChEMBL_461897 (CHEMBL929033) Agonist activity at MC4R
- ChEMBL_519599 (CHEMBL943674) Agonist activity at GPR40
- ChEMBL_535176 (CHEMBL988115) Agonist activity at GHSR
- ChEMBL_539581 (CHEMBL1035756) Agonist activity at PPARalpha
- ChEMBL_598674 (CHEMBL1050755) Agonist activity at GIPR
- ChEMBL_598678 (CHEMBL1050759) Agonist activity at PTHR
- ChEMBL_605056 (CHEMBL1071918) Agonist activity at mGluR1
- ChEMBL_605058 (CHEMBL1071920) Agonist activity at mGluR5
- ChEMBL_609753 (CHEMBL1069371) Agonist activity at NET
- ChEMBL_609754 (CHEMBL1069372) Agonist activity at DAT
- ChEMBL_609755 (CHEMBL1069373) Agonist activity at SERT
- ChEMBL_625709 (CHEMBL1103539) Agonist activity at TLR8
- ChEMBL_660467 (CHEMBL1250097) Agonist activity at FXR
- ChEMBL_674528 (CHEMBL1274439) Agonist activity at RARalpha
- ChEMBL_674529 (CHEMBL1274440) Agonist activity at RARbeta
- ChEMBL_674530 (CHEMBL1274441) Agonist activity at RARgamma
- ChEMBL_740553 (CHEMBL1764754) Agonist activity at PXR
- ChEMBL_750608 (CHEMBL1785454) Agonist activity at PPARalpha
- ChEMBL_756379 (CHEMBL1805405) Agonist activity at GPR109a
- ChEMBL_772828 (CHEMBL1837700) Agonist activity at TLR7
- ChEMBL_786503 (CHEMBL1921084) Agonist activity at FXR
- ChEMBL_793710 (CHEMBL1932524) Agonist activity at TRPV1
- ChEMBL_815240 (CHEMBL2025431) Agonist activity at TLR7
- ChEMBL_816615 (CHEMBL2025329) Agonist activity at MT1
- ChEMBL_822292 (CHEMBL2038446) Agonist activity at PPARalpha
- ChEMBL_822293 (CHEMBL2038596) Agonist activity at PPARdelta
- ChEMBL_834190 (CHEMBL2072930) Agonist activity at PPARalpha
- ChEMBL_854780 (CHEMBL2161911) Agonist activity at FXR
- ChEMBL_862589 (CHEMBL2173985) Agonist activity at GPR119
- ChEMBL_1462967 (CHEMBL3398677) Activation of human PPARgamma ligand binding domain expressed in COS7 cells by dual luciferase reporter gene assay
- ChEMBL_1501028 (CHEMBL3587209) Activity at human PPARgamma transfected in HEK293 cells assessed as transactivation activity by luciferase reporter gene assay
- ChEMBL_1630581 (CHEMBL3873287) Displacement of Fluoromone from GST-tagged recombinant human PPARgamma ligand binding domain by LanthaScreen TR-FRET assay
- ChEMBL_2216514 (CHEMBL5129646) Binding affinity to PPARgamma LBD (unknown origin) assessed as inhibition constant by HTRF based competitive binding assay
- ChEMBL_2372362 Binding affinity to PPARgamma (unknown origin) assessed as inhibition constant by TR-FRET based LanthaScreen competitive binding assay
- ChEMBL_987756 (CHEMBL2439847) Displacement of fluormone from human PPARgamma LBD expressed in Escherichia coli BL21 DE3 by fluorescence polarization assay
- ChEBML_1701995 Transactivation of human Gal4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
- ChEMBL_1934452 (CHEMBL4480104) Binding affinity to human 6xHis-tagged PPARgamma ligand binding domain (206 to 477 residues) by TR-FRET assay
- ChEMBL_1978260 (CHEMBL4611395) Transactivation of GAL4-fused human PPARgamma expressed in African green monkey CV1 cells by luciferase reporter gene assay
- ChEMBL_2208318 (CHEMBL5121267) Binding affinity to PPARgamma (unknown origin) assessed as inhibition constant by Lanthascreen TR-FRET assay relative to control
- ChEMBL_520070 (CHEMBL940691) Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assay
- ChEMBL_700497 (CHEMBL1648156) Transactivation of full length human PPARgamma expressed in african green monkey CV1 cells by luciferase reporter gene assay
- ChEMBL_875864 (CHEMBL2187602) Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assay
- ChEMBL_1770685 (CHEMBL4222797) Activity at PPARgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused to the PPARgamma ligand-binding domain assessed as inhibition of transcriptional activity after 18 hrs by luminescence-based luciferase reporter gene assay
- ChEBML_1572015 Agonist activity at FXR (unknown origin)
- ChEBML_1647937 Agonist activity at mouse FFA4 receptor
- ChEBML_1647938 Agonist activity at rat FFA4 receptor
- ChEBML_1647940 Agonist activity at mouse FFA1 receptor
- ChEBML_1647942 Agonist activity at rat FFA1 receptor
- ChEBML_1686618 Agonist activity at RXRaplha (unknown origin)
- ChEBML_1686619 Agonist activity at RXRbeta (unknown origin)
- ChEBML_1686620 Agonist activity at RXRgamma (unknown origin)
- ChEBML_1686646 Agonist activity at RARaplha (unknown origin)
- ChEBML_1686647 Agonist activity at RARbeta (unknown origin)
- ChEBML_1686648 Agonist activity at RARgamma (unknown origin)
- ChEBML_1687080 Agonist activity at CCR10 (unknown origin)
- ChEBML_1687081 Agonist activity at CCR2 (unknown origin)
- ChEBML_1687084 Agonist activity at CCR5 (unknown origin)
- ChEBML_1687095 Agonist activity at CXCR5 (unknown origin)
- ChEMBL_1275520 (CHEMBL3090535) Agonist activity at human PXR
- ChEMBL_1365355 (CHEMBL3292679) Agonist activity at human TGR5
- ChEMBL_1367589 Agonist activity at GPR52 (unknown origin)
- ChEMBL_1438933 (CHEMBL3382444) Agonist activity at human GPR119
- ChEMBL_1441405 (CHEMBL3373360) Agonist activity at rat NK3R
- ChEMBL_1701231 (CHEMBL4052213) Agonist activity at mouse MC3R
- ChEMBL_1701232 (CHEMBL4052214) Agonist activity at mouse MC4R
- ChEMBL_1738581 (CHEMBL4154331) Agonist activity at rat GPR40
- ChEMBL_1738582 (CHEMBL4154332) Agonist activity at mouse GPR40
- ChEMBL_1754035 (CHEMBL4188795) Agonist activity at human GPR40
- ChEMBL_1754037 (CHEMBL4188797) Agonist activity at mouse GPR40
- ChEMBL_1776558 (CHEMBL4233550) Agonist activity at human GPR120
- ChEMBL_1797287 (CHEMBL4269404) Agonist activity at human NLRP3
- ChEMBL_1832187 (CHEMBL4332195) Agonist activity at human PPARalpha
- ChEMBL_1832188 (CHEMBL4332196) Agonist activity at human PPARdelta
- ChEMBL_1832255 (CHEMBL4332263) Agonist activity at rat KISS1R
- ChEMBL_1837345 (CHEMBL4337478) Agonist activity at human MrgprX1
- ChEMBL_1837347 (CHEMBL4337480) Agonist activity at rat MRGPRC
- ChEMBL_1837348 (CHEMBL4337481) Agonist activity at mouse MRGPRC11
- ChEMBL_1909079 (CHEMBL4411525) Agonist activity at human TRPA1
- ChEMBL_1911939 (CHEMBL4414385) Agonist activity RXRalpha (unknown origin)
- ChEMBL_1911940 (CHEMBL4414386) Agonist activity RXRbeta (unknown origin)
- ChEMBL_1911941 (CHEMBL4414387) Agonist activity RXRgamma (unknown origin)
- ChEMBL_1911945 (CHEMBL4414391) Agonist activity LXRalpha (unknown origin)
- ChEMBL_1911946 (CHEMBL4414392) Agonist activity LXRbeta (unknown origin)
- ChEMBL_1911947 (CHEMBL4414393) Agonist activity FXR (unknown origin)
- ChEMBL_1913601 (CHEMBL4416184) Agonist activity at human PXR
- ChEMBL_1989313 (CHEMBL4623048) Agonist activity at human GPR119
- ChEMBL_1991080 (CHEMBL4624815) Agonist activity at human PPARdelta
- ChEMBL_1994275 (CHEMBL4628170) Agonist activity at mouse TRPV4
- ChEMBL_2016278 (CHEMBL4669856) Agonist activity at human SST4
- ChEMBL_2016279 (CHEMBL4669857) Agonist activity at human SST5
- ChEMBL_2016280 (CHEMBL4669858) Agonist activity at human SST1
- ChEMBL_2016281 (CHEMBL4669859) Agonist activity at human SST3
- ChEMBL_2026871 (CHEMBL4681029) Agonist activity at human CAR
- ChEMBL_2026876 (CHEMBL4681034) Agonist activity at human PXR
- ChEMBL_2026879 (CHEMBL4681037) Agonist activity at human VDR
- ChEMBL_2026880 (CHEMBL4681038) Agonist activity at human ER
- ChEMBL_2026881 (CHEMBL4681039) Agonist activity at human PR
- ChEMBL_2026882 (CHEMBL4681040) Agonist activity at human TR
- ChEMBL_2026883 (CHEMBL4681041) Agonist activity at human GR
- ChEMBL_2064212 (CHEMBL4719465) Agonist activity at mouse TAAR1
- ChEMBL_2091001 (CHEMBL4772264) Agonist activity at rat NPFFR1
- ChEMBL_2091002 (CHEMBL4772265) Agonist activity at rat NPFFR2
- ChEMBL_2132067 (CHEMBL4841582) Agonist activity at human SSTR2
- ChEMBL_2192403 (CHEMBL5104763) Agonist activity at human 5HT2b
- ChEMBL_2203297 (CHEMBL5116005) Agonist activity at human SST1
- ChEMBL_2203298 (CHEMBL5116006) Agonist activity at human SST2
- ChEMBL_2203299 (CHEMBL5116007) Agonist activity at human SST3
- ChEMBL_2203300 (CHEMBL5116008) Agonist activity at human SST4
- ChEMBL_2203301 (CHEMBL5116009) Agonist activity at rat SST5
- ChEMBL_2203822 (CHEMBL5116530) Agonist activity at mouse STING
- ChEMBL_2203826 (CHEMBL5116534) Agonist activity at human STING
- ChEMBL_2208431 (CHEMBL5121380) Agonist activity at mouse LXRbeta
- ChEMBL_2208452 (CHEMBL5121401) Agonist activity at human GPR119
- ChEMBL_2239361 (CHEMBL5153257) Agonist activity at human TRPV1
- ChEMBL_2239364 (CHEMBL5153260) Agonist activity at human TRPV4
- ChEMBL_2265951 Agonist activity at rat SST2 receptor
- ChEMBL_2265952 Agonist activity at dog SST2 receptor
- ChEMBL_2266636 Agonist activity at TLR2 (unknown origin)
- ChEMBL_2267540 Agonist activity at GPR40 (unknown origin)
- ChEMBL_2267541 Agonist activity at GPR120 (unknown origin)
- ChEMBL_2268355 Agonist activity at RXRalpha (unknown origin)
- ChEMBL_2268356 Agonist activity at RXRbeta (unknown origin)
- ChEMBL_2268357 Agonist activity at RXRgamma (unknown origin)
- ChEMBL_2268537 Agonist activity at VDR (unknown origin)
- ChEMBL_2273237 Agonist activity at 5HT1A (unknown origin)
- ChEMBL_2274184 Agonist activity at TLR8 (unknown origin)
- ChEMBL_2275386 Agonist activity at D4R (unknown origin)
- ChEMBL_2275387 Agonist activity at D3R (unknown origin)
- ChEMBL_2276112 Agonist activity at FXR (unknown origin)
- ChEMBL_2280117 Agonist activity at FFAR1 (unknown origin)
- ChEMBL_2281191 Agonist activity at human TLR7 receptor
- ChEMBL_2281192 Agonist activity at human TLR8 receptor
- ChEMBL_2281515 Agonist activity at PPARalpha (unknown origin)
- ChEMBL_2281517 Agonist activity at PPARdelta (unknown origin)
- ChEMBL_2282480 Agonist activity at EP3 (unknown origin)
- ChEMBL_2283982 Agonist activity at TLR8 (unknown origin)
- ChEMBL_2283990 Agonist activity at TLR7 (unknown origin)
- ChEMBL_2287219 Agonist activity at TGR5 (unknown origin)
- ChEMBL_2287261 Agonist activity at FXR (unknown origin)
- ChEMBL_2289549 Agonist activity at AhR (unknown origin)
- ChEMBL_2292792 Agonist activity at human recombinant TRPM8
- ChEMBL_2292793 Agonist activity at TRPM8 (unknown origin)
- ChEMBL_2292794 Agonist activity at TRPA1 (unknown origin)
- ChEMBL_2303320 Inverse agonist activity at human RORgammat
- ChEMBL_2304135 Agonist activity at FXR (unknown origin)
- ChEMBL_2304138 Agonist activity at PPARalpha (unknown origin)
- ChEMBL_2304157 Agonist activity at PPARdelta (unknown origin)
- ChEMBL_2321788 Inverse agonist activity at human H3R
- ChEMBL_2323057 Agonist activity at RORgammat (unknown origin)
- ChEMBL_2327065 Agonist activity at 5HT2B (unknown origin)
- ChEMBL_2327072 Agonist activity at human 5HT2A receptor
- ChEMBL_2331719 Agonist activity at TLR8 (unknown origin)
- ChEMBL_2331720 Agonist activity at TLR7 (unknown origin)
- ChEMBL_2346685 Agonist activity at PPARalpha (unknown origin)
- ChEMBL_2346686 Agonist activity at PPARdelta (unknown origin)
- ChEMBL_2349902 Agonist activity at MOR (unknown origin)
- ChEMBL_2354067 Agonist activity at PXR (unknown origin)
- ChEMBL_2376400 Agonist activity at FXR (unknown origin)
- ChEMBL_2422156 Agonist activity at human PPAR gamma
- ChEMBL_2426870 Agonist activity at PARG (unknown origin)
- ChEMBL_2434314 Agonist activity at AMPK (unknown origin)
- ChEMBL_2437613 Agonist activity at TLR7 (unknown origin)
- ChEMBL_2468400 Agonist activity at NOD2 (unknown origin)
- ChEMBL_2483562 Agonist activity at FXR (unknown origin)
- ChEMBL_2487375 Agonist activity at RXRalpha (unknown origin)
- ChEMBL_2487376 Agonist activity at RXRbeta (unknown origin)
- ChEMBL_2487377 Agonist activity at RXRgamma (unknown origin)
- ChEMBL_2492830 Agonist activity at TRPA1 (unknown origin)
- ChEMBL_2502712 Agonist activity at RXRbeta (unknown origin)
- ChEMBL_2502713 Agonist activity at RXRgamma (unknown origin)
- ChEMBL_2503692 Agonist activity at STING (unknown origin)
- ChEMBL_339212 (CHEMBL866559) Agonist potency at MC4 receptor
- ChEMBL_389723 (CHEMBL868030) Agonist activity at human H2R
- ChEMBL_395993 (CHEMBL910338) Agonist activity at human MC1R
- ChEMBL_395995 (CHEMBL910340) Agonist activity at human MC3R
- ChEMBL_395997 (CHEMBL910342) Agonist activity at human MC4R
- ChEMBL_438312 (CHEMBL887414) Agonist activity at human AR
- ChEMBL_440538 (CHEMBL889637) Agonist activity at human CB2R
- ChEMBL_448111 (CHEMBL898367) Agonist activity at ghrelin receptor
- ChEMBL_449509 (CHEMBL899776) Agonist activity at ghrelin receptor
- ChEMBL_461176 (CHEMBL945121) Agonist activity at mGlu2 receptor
- ChEMBL_471738 (CHEMBL921010) Agonist activity at CB1 receptor
- ChEMBL_471739 (CHEMBL921011) Agonist activity at CB2 receptor
- ChEMBL_478517 (CHEMBL922479) Agonist activity at human PPARalpha
- ChEMBL_479602 (CHEMBL926798) Agonist activity at TPO receptor
- ChEMBL_491617 (CHEMBL945388) Agonist activity at GHS receptor
- ChEMBL_498031 (CHEMBL1000234) Agonist activity at PPARalpha receptor
- ChEMBL_502100 (CHEMBL983225) Agonist activity at rat PPARalpha
- ChEMBL_502101 (CHEMBL983226) Agonist activity at mouse PPARalpha
- ChEMBL_514046 (CHEMBL979069) Agonist activity at sst4 receptor
- ChEMBL_514050 (CHEMBL979073) Agonist activity at 5HT1A receptor
- ChEMBL_514051 (CHEMBL979074) Agonist activity at 5HT2B receptor
- ChEMBL_514296 (CHEMBL979126) Agonist activity at NK1 receptor
- ChEMBL_520083 (CHEMBL943687) Agonist activity at mouse PPARalpha
- ChEMBL_520085 (CHEMBL943689) Agonist activity at dog PPARalpha
- ChEMBL_523646 (CHEMBL998017) Agonist activity at androgen receptor
- ChEMBL_531312 (CHEMBL989724) Agonist activity at CB1 receptor
- ChEMBL_552261 (CHEMBL995591) Agonist activity at human PXR
- ChEMBL_591060 (CHEMBL1052813) Agonist activity at recombinant GluR5
- ChEMBL_591061 (CHEMBL1052814) Agonist activity at recombinant GluR6
- ChEMBL_598675 (CHEMBL1050756) Agonist activity at glucagon receptor
- ChEMBL_608753 (CHEMBL1067766) Agonist activity at 5HT1A receptor
- ChEMBL_625154 (CHEMBL1115175) Agonist activity at 5HT2C receptor
- ChEMBL_625299 (CHEMBL1109737) Agonist activity at 5HT2B receptor
- ChEMBL_625301 (CHEMBL1109739) Agonist activity at 5HT2A receptor
- ChEMBL_627990 (CHEMBL1105511) Agonist activity at GluA1 receptor
- ChEMBL_627991 (CHEMBL1105512) Agonist activity at GluA2 receptor
- ChEMBL_627992 (CHEMBL1105513) Agonist activity at GluA3 receptor
- ChEMBL_630082 (CHEMBL1110002) Agonist activity at human BRS3
- ChEMBL_630084 (CHEMBL1110004) Agonist activity at mouse BRS3
- ChEMBL_634710 (CHEMBL1118795) Agonist activity at alpha4beta2 nAChR
- ChEMBL_661952 (CHEMBL1252556) Agonist activity at CB2 receptor
- ChEMBL_675610 (CHEMBL1273918) Agonist activity at motilin receptor
- ChEMBL_684663 (CHEMBL1285630) Agonist activity at GluR2 receptor
- ChEMBL_718713 (CHEMBL1680932) Agonist activity at human GPR109b
- ChEMBL_718716 (CHEMBL1680935) Agonist activity at rat GPR109a
- ChEMBL_718717 (CHEMBL1680936) Agonist activity at mouse GPR109a
- ChEMBL_743285 (CHEMBL1767484) Agonist activity at P2Y2 receptor
- ChEMBL_743286 (CHEMBL1767485) Agonist activity at P2Y4 receptor
- ChEMBL_743287 (CHEMBL1767486) Agonist activity at P2Y6 receptor
- ChEMBL_745347 (CHEMBL1775467) Agonist activity at M2 receptor
- ChEMBL_745348 (CHEMBL1775468) Agonist activity at M3 receptor
- ChEMBL_745349 (CHEMBL1775469) Agonist activity at M4 receptor
- ChEMBL_745350 (CHEMBL1775470) Agonist activity at M5 receptor
- ChEMBL_746070 (CHEMBL1775457) Agonist activity at CB2 receptor
- ChEMBL_748957 (CHEMBL1781405) Agonist activity at motilin receptor
- ChEMBL_750607 (CHEMBL1786471) Partial agonist activity at PPARdelta
- ChEMBL_751026 (CHEMBL1786811) Agonist activity at human P2Y2
- ChEMBL_751027 (CHEMBL1786812) Agonist activity at human P2Y4
- ChEMBL_774918 (CHEMBL1913363) Agonist activity at S1P1 receptor
- ChEMBL_774919 (CHEMBL1913364) Agonist activity at S1P2 receptor
- ChEMBL_774921 (CHEMBL1913366) Agonist activity at S1P5 receptor
- ChEMBL_788421 (CHEMBL1918186) Agonist activity at estrogen receptor
- ChEMBL_796444 (CHEMBL1937759) Agonist activity at dog PPARalpha
- ChEMBL_796446 (CHEMBL1937761) Agonist activity at dog PPARdelta
- ChEMBL_796450 (CHEMBL1937765) Agonist activity at rat PPARalpha
- ChEMBL_796453 (CHEMBL1937768) Agonist activity at mouse PPARalpha
- ChEMBL_796455 (CHEMBL1937770) Agonist activity at mouse PPARdelta
- ChEMBL_797513 (CHEMBL1943343) Agonist activity at rat GPR40
- ChEMBL_797514 (CHEMBL1943344) Agonist activity at mouse GPR40
- ChEMBL_798318 (CHEMBL1943806) Agonist activity at human HM74A
- ChEMBL_802539 (CHEMBL1952575) Agonist activity at human S1P5R
- ChEMBL_819765 (CHEMBL2034277) Agonist activity at SIP3 receptor
- ChEMBL_819766 (CHEMBL2034278) Agonist activity at SIP1 receptor
- ChEMBL_820674 (CHEMBL2037945) Agonist activity at human GPR109b
- ChEMBL_820675 (CHEMBL2037946) Agonist activity at rat GPR109a
- ChEMBL_820676 (CHEMBL2037947) Agonist activity at mouse GPR109a
- ChEMBL_830238 (CHEMBL2060789) Agonist activity at mouse GPR120
- ChEMBL_834193 (CHEMBL2072933) Agonist activity at human PPARalpha
- ChEMBL_834194 (CHEMBL2072934) Agonist activity at rat PPARalpha
- ChEMBL_850286 (CHEMBL2150706) Agonist activity at monkey GPR81
- ChEMBL_850287 (CHEMBL2150707) Agonist activity at dog GPR81
- ChEMBL_850288 (CHEMBL2150708) Agonist activity at rat GPR81
- ChEMBL_850289 (CHEMBL2150709) Agonist activity at mouse GPR81
- ChEMBL_851151 (CHEMBL2157808) Agonist activity at alpha7 nAChR
- ChEMBL_879207 (CHEMBL2208520) Agonist activity at ghrelin receptor
- ChEMBL_886913 (CHEMBL2211869) Agonist activity at S1P4 receptor
- ChEMBL_886914 (CHEMBL2211870) Agonist activity at S1P5 receptor
- ChEMBL_933765 (CHEMBL2321101) Agonist activity at mouse TLR7
- ChEMBL_973264 (CHEMBL2412443) Agonist activity at human VDR
- ChEMBL_985965 (CHEMBL2432197) Agonist activity at mouse GPR142
- ChEMBL_2213704 (CHEMBL5126836) Inverse agonist activity at human A2A receptor assessed as inhibition of selective agonist-induced cAMP production
- ChEMBL_1463123 (CHEMBL3399106) Binding affinity to PPARgamma (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization binding assay
- ChEMBL_1747074 (CHEMBL4181584) Activation of human PPARgamma LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assay
- ChEMBL_1804110 (CHEMBL4276402) Transactivation of PPARgamma (unknown origin) transfected in human DRO cells after 24 hrs by dual luciferase reporter gene assay
- ChEMBL_1920581 (CHEMBL4423426) Transactivation of GAL4-fused human PPARgamma LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assay
- ChEMBL_1977610 (CHEMBL4610745) Competitive binding affinity to GST-tagged human PPARgamma LBD incubated for 1 to 6 hrs by TR-FRET assay
- ChEMBL_1978686 (CHEMBL4611821) Activation of human PPARgamma expressed in HEK293 cells incubated for 18 hrs by luciferase reporter assay relative to control
- ChEMBL_2269565 Displacement of fluormone pan-PPARgreen from GST-tagged human PPARgamma ligand binding domain by LanthaScreen TR-FRET competitive binding assay
- ChEMBL_2157888 (CHEMBL5042638) Agonist activity at recombinant N-terminal His6 -tagged GFP fused PPARgamma LBD (unknown origin) (203 to 477 residues) expressed in Escherichia cell Rosetta2 using biotinylated NLVPDAASKHKQLSELLRGGSGS peptide as substrate assessed as induction of Tb cryptate labelled CBP recruitment measured after 2 hrs by HTRF assay
- ChEBML_105700 Agonist potency for human Melanocortin 1 receptor
- ChEBML_106176 Agonist potency towards human Melanocortin 4 receptor
- ChEBML_106686 Agonist activity against human melanocortin receptor hMC4R
- ChEBML_106815 Agonist activity at human melanocortin receptor (hMC1R).
- ChEBML_200522 Agonist activity on human somatostatin receptor 5
- ChEMBL_1328815 (CHEMBL3227399) Agonist activity at TSHR (unknown origin)
- ChEMBL_1328819 (CHEMBL3227403) Agonist activity at LHCGR (unknown origin)
- ChEMBL_1334664 (CHEMBL3239864) Agonist activity at human CB2 receptor
- ChEMBL_1334665 (CHEMBL3238548) Agonist activity at human CB1 receptor
- ChEMBL_1336217 (CHEMBL3241465) Agonist activity at human H4 receptor
- ChEMBL_1349372 (CHEMBL3269595) Agonist activity at human PPAR-alpha
- ChEMBL_1434023 (CHEMBL3381495) Agonist activity at KOR (unknown origin)
- ChEMBL_1434024 (CHEMBL3381496) Agonist activity at MOR (unknown origin)
- ChEMBL_1435149 (CHEMBL3389500) Agonist activity at TRPM8 (unknown origin)
- ChEMBL_1502320 (CHEMBL3591554) Agonist activity at LXRalpha (unknown origin)
- ChEMBL_1502322 (CHEMBL3591556) Agonist activity at LXRbeta (unknown origin)
- ChEMBL_1543493 (CHEMBL3750340) Agonist activity at FXR (unknown origin)
- ChEMBL_1543494 (CHEMBL3750341) Agonist activity at PPARalpha (unknown origin)
- ChEMBL_1543496 (CHEMBL3750343) Agonist activity at RXRalpha (unknown origin)
- ChEMBL_1549761 (CHEMBL3757317) Agonist activity at human EP2 receptor
- ChEMBL_1549762 (CHEMBL3757318) Agonist activity at human EP3 receptor
- ChEMBL_1549763 (CHEMBL3757319) Agonist activity at human EP4 receptor
- ChEMBL_1573253 (CHEMBL3803493) Agonist activity at S1PR2 (unknown origin)
- ChEMBL_1573254 (CHEMBL3803494) Agonist activity at S1PR4 (unknown origin)
- ChEMBL_1573255 (CHEMBL3803495) Agonist activity at S1PR5 (unknown origin)
- ChEMBL_1589943 (CHEMBL3830933) Agonist activity at mouse PPAR-alpha
- ChEMBL_1589944 (CHEMBL3830934) Agonist activity at rat PPAR-alpha
- ChEMBL_1590849 (CHEMBL3830233) Agonist activity at FXR (unknown origin)
- ChEMBL_1662502 (CHEMBL4012183) Agonist activity at FFA1 (unknown origin)
- ChEMBL_1687080 (CHEMBL4037559) Agonist activity at CCR10 (unknown origin)
- ChEMBL_1687081 (CHEMBL4037560) Agonist activity at CCR2 (unknown origin)
- ChEMBL_1687082 (CHEMBL4037561) Agonist activity at CCR3 (unknown origin)
- ChEMBL_1687083 (CHEMBL4037562) Agonist activity at CCR4 (unknown origin)
- ChEMBL_1687084 (CHEMBL4037563) Agonist activity at CCR5 (unknown origin)
- ChEMBL_1687085 (CHEMBL4037564) Agonist activity at CCR6 (unknown origin)
- ChEMBL_1687087 (CHEMBL4037566) Agonist activity at CCR8 (unknown origin)
- ChEMBL_1687088 (CHEMBL4037567) Agonist activity at CCR9 (unknown origin)
- ChEMBL_1687091 (CHEMBL4037570) Agonist activity at CXCR1 (unknown origin)
- ChEMBL_1687093 (CHEMBL4037572) Agonist activity at CXCR3 (unknown origin)
- ChEMBL_1687094 (CHEMBL4037573) Agonist activity at CXCR4 (unknown origin)
- ChEMBL_1687096 (CHEMBL4037575) Agonist activity at CXCR6 (unknown origin)
- ChEMBL_1687097 (CHEMBL4037576) Agonist activity at CXCR7 (unknown origin)
- ChEMBL_1735781 (CHEMBL4151317) Agonist activity at GPR120 (unknown origin)
- ChEMBL_1771596 (CHEMBL4223708) Agonist activity at GPR119 (unknown origin)
- ChEMBL_1778942 (CHEMBL4235934) Agonist activity at GPR119 (unknown origin)
- ChEMBL_1793310 (CHEMBL4265229) Agonist activity at GPR40 (unknown origin)
- ChEMBL_1793313 (CHEMBL4265232) Agonist activity at GPR119 (unknown origin)
- ChEMBL_1824675 (CHEMBL4324439) Agonist activity at AhR (unknown origin)
- ChEMBL_1843845 (CHEMBL4344272) Agonist activity at PPARalpha (unknown origin)
- ChEMBL_1843847 (CHEMBL4344274) Agonist activity at PPARdelta (unknown origin)
- ChEMBL_1843848 (CHEMBL4344275) Agonist activity at FXR (unknown origin)
- ChEMBL_1871300 (CHEMBL4372467) Partial agonist activity at human D1R
- ChEMBL_1875038 (CHEMBL4376327) Agonist activity at human GLP1 receptor
- ChEMBL_1904570 (CHEMBL4406928) Agonist activity at human beta2 adrenoceptor
- ChEMBL_1935004 (CHEMBL4480763) Agonist activity at human CB2 receptor
- ChEMBL_1935005 (CHEMBL4480764) Agonist activity at human CB1 receptor
- ChEMBL_1978547 (CHEMBL4611682) Agonist activity at human GPR109A receptor
- ChEMBL_1984146 (CHEMBL4617552) Agonist activity at PXR (unknown origin)
- ChEMBL_1986873 (CHEMBL4620420) Agonist activity at TRPA1 (unknown origin)
- ChEMBL_1991084 (CHEMBL4624819) Agonist activity at PPARdelta (unknown origin)
- ChEMBL_1991113 (CHEMBL4624848) Agonist activity at GPR40 (unknown origin)
- ChEMBL_1994669 (CHEMBL4628564) Agonist activity at D2S (unknown origin)
- ChEMBL_2022928 (CHEMBL4676741) Agonist activity at rat alpha4beta2 nAChR
- ChEMBL_2023169 (CHEMBL4676982) Agonist activity at rat alpha7 nAChR
- ChEMBL_2033605 (CHEMBL4687763) Agonist activity at TLR2 (unknown origin)
- ChEMBL_2064690 (CHEMBL4719943) Agonist activity at mGlu2 (unknown origin)
- ChEMBL_2064691 (CHEMBL4719944) Agonist activity at mGlu3 (unknown origin)
- ChEMBL_2070262 (CHEMBL4725796) Agonist activity at S1P1 (unknown origin)
- ChEMBL_2070263 (CHEMBL4725797) Agonist activity at S1P3 (unknown origin)
- ChEMBL_2080002 (CHEMBL4735793) Agonist activity at CB1 (unknown origin)
- ChEMBL_2080003 (CHEMBL4735794) Agonist activity at CB2 (unknown origin)
- ChEMBL_2100276 (CHEMBL4808672) Agonist activity at FFAR2 (unknown origin)
- ChEMBL_2100277 (CHEMBL4808673) Agonist activity at FFAR3 (unknown origin)
- ChEMBL_2100278 (CHEMBL4808674) Agonist activity at FFAR4 (unknown origin)
- ChEMBL_2130215 (CHEMBL4839644) Agonist activity at RORalpha (unknown origin)
- ChEMBL_2130216 (CHEMBL4839645) Agonist activity at RORbeta (unknown origin)
- ChEMBL_2160008 (CHEMBL5044758) Agonist activity at PPARalpha (unknown origin)
- ChEMBL_2160009 (CHEMBL5044759) Agonist activity at PPARdelta (unknown origin)
- ChEMBL_2185284 (CHEMBL5097366) Agonist activity at FFAR1 (unknown origin)
- ChEMBL_2198170 (CHEMBL5110686) Agonist activity at GPER (unknown origin)
- ChEMBL_2203815 (CHEMBL5116523) Agonist activity at STING (unknown origin)
- ChEMBL_2208410 (CHEMBL5121359) Agonist activity at AhR (unknown origin)
- ChEMBL_2208447 (CHEMBL5121396) Agonist activity at GPR119 (unknown origin)
- ChEMBL_2219723 (CHEMBL5133057) Agonist activity at human CysLT1 receptor
- ChEMBL_2219724 (CHEMBL5133058) Agonist activity at human CysLT2 receptor
- ChEMBL_2220531 (CHEMBL5133865) Agonist activity at OX1R (unknown origin)
- ChEMBL_2220534 (CHEMBL5133868) Agonist activity at OX2R (unknown origin)
- ChEMBL_2227385 (CHEMBL5140898) Agonist activity at human Androgen receptor
- ChEMBL_2227401 (CHEMBL5140914) Agonist activity at rat Androgen receptor
- ChEMBL_2227570 (CHEMBL5141083) Agonist activity at Nurr1 (unknown origin)
- ChEMBL_2234836 (CHEMBL5148608) Agonist activity at PXR (unknown origin)
- ChEMBL_2239328 (CHEMBL5153224) Agonist activity at TRPM5 (unknown origin)
- ChEMBL_2242293 (CHEMBL5156503) Agonist activity at PXR (unknown origin)
- ChEMBL_2243121 (CHEMBL5157331) Agonist activity at PPARalpha (unknown origin)
- ChEMBL_2243123 (CHEMBL5157333) Agonist activity at PPARdelta (unknown origin)
- ChEMBL_2243124 (CHEMBL5157334) Agonist activity at PXR (unknown origin)
- ChEMBL_2261592 (CHEMBL5216603) Agonist activity at GPR40 (unknown origin)
- ChEMBL_2266638 Agonist activity at TLR2/TLR1 (unknown origin)
- ChEMBL_2268364 Inverse agonist activity at TLX (unknown origin)
- ChEMBL_2269654 Agonist activity at SMO receptor (unknown origin)
- ChEMBL_2272277 Agonist activity at 5HT1A (unknown origin) receptor
- ChEMBL_2276102 Agonist activity at FXR in HEK293 cells
- ChEMBL_2282481 Agonist activity at FP receptor (unknown origin)
- ChEMBL_2297266 Agonist activity at human melanocortin receptor 3
- ChEMBL_2297267 Agonist activity at human melanocortin receptor 4
- ChEMBL_2297268 Agonist activity at human melanocortin receptor 5
- ChEMBL_2300747 Agonist activity at rat M1 muscarinic receptor
- ChEMBL_2300748 Agonist activity at rat M2 muscarinic receptor
- ChEMBL_2302385 Agonist activity against PPAR-alpha (unknown origin)
- ChEMBL_2444527 Agonist activity against rat mGlu4 R60A mutant
- ChEMBL_2444528 Agonist activity against rat mGlu4 K74A mutant
- ChEMBL_2444529 Agonist activity against rat mGlu4 S160A mutant
- ChEMBL_2444530 Agonist activity against rat mGlu4 S160D mutant
- ChEMBL_2444531 Agonist activity at rat mGlu4 R258A mutant
- ChEMBL_2444535 Agonist activity at rat mGlu7 K60A mutant
- ChEMBL_2444537 Agonist activity at rat mGlu7 N74A mutant
- ChEMBL_2444538 Agonist activity at rat mGlu7 N74K mutant
- ChEMBL_2444539 Agonist activity at rat mGlu7 S160A mutant
- ChEMBL_2444540 Agonist activity at rat mGlu7 Q258A mutant
- ChEMBL_2476259 Agonist activity at human Pregnane X receptor
- ChEMBL_2496287 Agonist activity at THR-beta (unknown origin)
- ChEMBL_389725 (CHEMBL868032) Agonist activity at guinea pig H2R
- ChEMBL_436457 (CHEMBL904763) Agonist activity at rat CB2 receptor
- ChEMBL_453611 (CHEMBL885611) Agonist activity at rat 5HT1A receptor
- ChEMBL_454761 (CHEMBL886789) Agonist activity at human GHS-R1
- ChEMBL_464142 (CHEMBL948304) Agonist activity at mu opioid receptor
- ChEMBL_464500 (CHEMBL931999) Agonist activity at adenosine A2A receptor
- ChEMBL_465243 (CHEMBL933037) Agonist activity at human MC4 receptor
- ChEMBL_477389 (CHEMBL928177) Agonist activity at human CB2 receptor
- ChEMBL_489766 (CHEMBL989249) Agonist activity against mouse CCK1 receptor
- ChEMBL_490133 (CHEMBL994438) Agonist activity against human CCK1 receptor
- ChEMBL_492754 (CHEMBL938553) Agonist activity at muscarinic M1 receptor
- ChEMBL_492756 (CHEMBL939444) Agonist activity at muscarinic M2 receptor
- ChEMBL_492758 (CHEMBL939446) Agonist activity at muscarinic M3 receptor
- ChEMBL_492760 (CHEMBL939448) Agonist activity at muscarinic M4 receptor
- ChEMBL_492762 (CHEMBL939450) Agonist activity at muscarinic M5 receptor
- ChEMBL_495127 (CHEMBL1008906) Agonist activity at human Ghrelin receptor
- ChEMBL_513418 (CHEMBL976505) Agonist activity at human CCK1 receptor
- ChEMBL_513421 (CHEMBL976508) Agonist activity at mouse CCK1 receptor
- ChEMBL_514297 (CHEMBL979127) Agonist activity at mu opioid receptor
- ChEMBL_514298 (CHEMBL979128) Agonist activity at histamine H1 receptor
- ChEMBL_514299 (CHEMBL979129) Agonist activity at muscarinic M1 receptor
- ChEMBL_536125 (CHEMBL983579) Agonist activity at muscarinic M1 receptor
- ChEMBL_536129 (CHEMBL983583) Agonist activity at muscarinic M2 receptor
- ChEMBL_536130 (CHEMBL983584) Agonist activity at muscarinic M3 receptor
- ChEMBL_536131 (CHEMBL983585) Agonist activity at muscarinic M4 receptor
- ChEMBL_536132 (CHEMBL983586) Agonist activity at muscarinic M5 receptor
- ChEMBL_555222 (CHEMBL965359) Agonist activity at kappa opioid receptor
- ChEMBL_558727 (CHEMBL954129) Agonist activity against human alpha4beta2 nAChR
- ChEMBL_558728 (CHEMBL954130) Agonist activity against human alpha3beta4 nAChR
- ChEMBL_559554 (CHEMBL1019857) Inverse agonist activity at CB2 receptor
- ChEMBL_560056 (CHEMBL1022443) Agonist activity at human CB2 receptor
- ChEMBL_560058 (CHEMBL1022445) Agonist activity at human CB1 receptor
- ChEMBL_565972 (CHEMBL963246) Agonist activity at mu opioid receptor
- ChEMBL_572400 (CHEMBL1036136) Agonist activity at dog PPARalpha receptor
- ChEMBL_581548 (CHEMBL1060747) Agonist activity at human EP3 receptor
- ChEMBL_582724 (CHEMBL1054986) Agonist activity at human P2Y12 receptor
- ChEMBL_588078 (CHEMBL1041330) Agonist activity at dopamine D1 receptor
- ChEMBL_599591 (CHEMBL1040203) Agonist activity at 5-HT2A receptor
- ChEMBL_605640 (CHEMBL1070562) Agonist activity at human CB2 receptor
- ChEMBL_605642 (CHEMBL1070564) Agonist activity at human CB1 receptor
- ChEMBL_608752 (CHEMBL1067765) Agonist activity at dopamine D2 receptor
- ChEMBL_622562 (CHEMBL1117506) Agonist activity at human ghrelin receptor
- ChEMBL_641621 (CHEMBL1176323) Agonist activity at human TRPV1 receptor
- ChEMBL_675993 (CHEMBL1272931) Agonist activity at human MC4 receptor
- ChEMBL_744893 (CHEMBL1772914) Agonist activity at dog 5HT2C receptor
- ChEMBL_772747 (CHEMBL1837359) Agonist activity at human V2 receptor
- ChEMBL_775977 (CHEMBL1912975) Agonist activity at rat androgen receptor
- ChEMBL_833017 (CHEMBL2067156) Agonist activity at alpha4beta 2 nAChR
- ChEMBL_839559 (CHEMBL2090366) Agonist activity at human P2Y6 receptor
- ChEMBL_877928 (CHEMBL2188604) Agonist activity at human alpha7 nAChR
- ChEMBL_877930 (CHEMBL2188606) Agonist activity at human alpha4beta2 nAChR
- ChEMBL_938636 (CHEMBL2327256) Agonist activity at GluK2 (unknown origin)
- ChEMBL_938803 (CHEMBL2327947) Agonist activity at GluA1 (unknown origin)
- ChEMBL_938804 (CHEMBL2327948) Agonist activity at GluK1 (unknown origin)
- ChEMBL_938821 (CHEMBL2328090) Agonist activity at TRPV4 (unknown origin)
- ChEMBL_985759 (CHEMBL2433976) Agonist activity at TRPA1 (unknown origin)
- ChEMBL_987709 (CHEMBL2439687) Agonist activity at TGR5 (unknown origin)
- ChEMBL_992061 (CHEMBL2447704) Agonist activity at human Y4 receptor