TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetRapamycin-insensitive companion of mTOR/Serine/threonine-protein kinase mTOR/Target of rapamycin complex 2 subunit MAPKAP1/Target of rapamycin complex subunit LST8(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC2 in HEK293 cells using GST-tagged S6K1 or Akt1 as substrate after 30 mins by immunoblotting assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunob...More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC2 in human HEK293 cells assessed as decrease in phosphorylated Akt level incubated for 30 mins by immunoblot assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunob...More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of mTORC2 in HEK293T/17 cells assessed as reduction in Akt phosphorylation at Ser-473 residue after 2 hrs by sandwich immunoassayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: <32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant mTORC2 (unknown origin) expressed in Escherichia coli after 15 mins in presence of gamma-[32]P-ATP by high-throughput scree...More data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair