Report error Found 174 with Last Name = 'lavogina' and Initial = 'd'
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataKi: 0.00700nMAssay Description:Covalent inhibition of human recombinant PKAC-alpha assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0155nM ΔG°: -62.7kJ/mole IC50: 3.88nMT: 30°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataKi: 0.0230nMAssay Description:Covalent inhibition of human recombinant PKAC-alpha assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.136nM ΔG°: -57.3kJ/mole IC50: 34.2nMT: 30°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataKi: 0.630nMAssay Description:Covalent inhibition of human recombinant PKAC-alpha assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.86nM ΔG°: -50.7kJ/mole IC50: 1.78E+3nMT: 30°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
Affinity DataKi: 2.17nM ΔG°: -50.3kJ/mole IC50: 2.07E+3nMT: 30°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Covalent inhibition of human recombinant PKAC-alpha assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMT: 30°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM). Subseque...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMT: 30°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM). Subseque...More data for this Ligand-Target Pair
Affinity DataIC50: 2.41nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Displacement of fluorescent-ARC-1063 from His6-tagged recombinant human ROCK2 by luminescence intensity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
Affinity DataIC50: 5.32nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of ARC-1063 fluorescent probe binding to recombinant human PKAC-alpha incubated for 1 hr by time-gated luminescence intensity based displa...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human p70S6K by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human p70S6K by fluorescence anisotropy assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptideMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of fluorescent-ARC-1063 from His6-tagged recombinant human ROCK2 by luminescence intensity assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 12.9nMAssay Description:Inhibition of cAPK Calpha in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 13.4nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 14.6nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21.1nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of ARC-1063 fluorescent probe binding to recombinant human PKAC-alpha incubated for 1 hr by time-gated luminescence intensity based displa...More data for this Ligand-Target Pair
Affinity DataIC50: 30.7nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36.9nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human PKG1alpha by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43.1nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 56.6nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human MSK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Displacement of fluorescent-ARC-583/ARC-1042/ARC-1059 from His6-tagged recombinant human MSK1 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 97.3nMAssay Description:Inhibition of cAPK Calpha in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...More data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Displacement of fluorescent-ARC-1063 from His6-tagged recombinant human ROCK2 by luminescence intensity assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
University of Tartu
Curated by ChEMBL
University of Tartu
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of ARC-1063 fluorescent probe binding to recombinant human PKAC-alpha incubated for 1 hr by time-gated luminescence intensity based displa...More data for this Ligand-Target Pair