Report error Found 179 with Last Name = 'sechler' and Initial = 'j'
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against c-ABLMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against PDGFRalphaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMpH: 8.0 T: 30°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against LCKMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 168nMpH: 8.0 T: 30°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Inhibitory activity against c-SRCMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 188nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
Affinity DataIC50: 189nMpH: 8.0 T: 30°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 217nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 266nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 268nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Affinity DataIC50: 293nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair