Compile Data Set for Download or QSAR
maximum 50k data
Found 16 of ki for UniProtKB: O88871
LigandPNGBDBM24198(3-aminopropylphosphinic derivative, (R)-8 | [(2R)-...)
Affinity DataKi:  4.30nM ΔG°:  -11.3kcal/mole EC50:  14nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24195(3-aminopropylphosphinic derivative, (R)-7 | AZD335...)
Affinity DataKi:  5.10nM ΔG°:  -11.2kcal/mole EC50:  8.64nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24193((3-amino-2-fluoropropyl)phosphinic acid | 3-aminop...)
Affinity DataKi:  10nM ΔG°:  -10.8kcal/mole EC50:  15nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24196((3-amino-2-fluoropropyl)(methyl)phosphinic acid | ...)
Affinity DataKi:  14nM ΔG°:  -10.6kcal/mole EC50:  23nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)
Affinity DataKi:  15nM ΔG°:  -10.6kcal/mole EC50:  19nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24185((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)
Affinity DataKi:  33nM ΔG°:  -10.1kcal/mole EC50:  41nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
LigandPNGBDBM24191((3-amino-2-oxopropyl)phosphinic acid | (3-amino-2-...)
Affinity DataKi:  48nM ΔG°:  -9.88kcal/mole EC50:  81nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)
Affinity DataKi:  50nM ΔG°:  -9.85kcal/mole EC50:  130nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24194(3-aminopropylphosphinic derivative, (S)-7 | [(2S)-...)
Affinity DataKi:  70nM ΔG°:  -9.66kcal/mole EC50:  250nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)
Affinity DataKi:  94nM ΔG°:  -9.48kcal/mole EC50:  220nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Affinity DataKi:  180nM ΔG°:  -9.10kcal/mole EC50:  150nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24192((3-amino-2-oxopropyl)(methyl)phosphinic acid | (3-...)
Affinity DataKi:  200nM ΔG°:  -9.04kcal/mole EC50:  270nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataKi:  220nM ΔG°:  -8.98kcal/mole EC50:  750nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
LigandPNGBDBM24197(3-aminopropylphosphinic derivative, (S)-8 | [(2S)-...)
Affinity DataKi:  480nM ΔG°:  -8.53kcal/mole EC50:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)
Affinity DataKi:  840nM ΔG°:  -8.20kcal/mole EC50:  600nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)
Affinity DataKi:  2.10E+3nM ΔG°:  -7.66kcal/mole EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed