BDBM24184 (3-aminopropyl)phosphinic acid::3-aminopropylphosphinic derivative, 1::CGP27492::CHEMBL112203

SMILES NCCCP(O)=O

InChI Key InChIKey=ZTHNRNOOZGJLRR-UHFFFAOYSA-N

Data  3 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 24184   

LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataIC50: 5nMAssay Description:Inhibition of binding of [3H]CGP-27492 to gamma-aminobutyric acid type B receptor of rat cortex.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataIC50: 3nMAssay Description:In vitro displacement of [3H]GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
In DepthDetails
PubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataKi:  15nM ΔG°:  -10.6kcal/mole EC50:  19nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(Human)
University of Sydney

Curated by PDSP Ki Database
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataKi:  2.47E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed