Found 7 of ic50 for monomerid = 50148827 TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli in presence of NAD+ by enzyme coup...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human SIRT2 using RHKK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resid...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT5 (37 to 310 end residues) expressed in Escherichia coli using Ac-K(Succ)-AMC as substrate ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT1 using RHKK(Ac)-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Imperial College
Curated by ChEMBL
Imperial College
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged SIRT3 (101 to 399 residues) expressed in Escherichia coli using p53 derived (379 to 382 residue...More data for this Ligand-Target Pair
