Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 50553944
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera

Curated by ChEMBL
LigandPNGBDBM50553944(CHEMBL4780624)
Affinity DataIC50:  33nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera

Curated by ChEMBL
LigandPNGBDBM50553944(CHEMBL4780624)
Affinity DataIC50:  36nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera

Curated by ChEMBL
LigandPNGBDBM50553944(CHEMBL4780624)
Affinity DataIC50:  160nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed