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Found 4 Enz. Inhib. hit(s) with Target = '2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase' and Ligand = 'BDBM50484527'
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50484527(CHEMBL1928286)
Affinity DataIC50:  440nMAssay Description:Inhibition of Escherichia coli HPPK using [alpha-33P]ATP after 30 minsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50484527(CHEMBL1928286)
Affinity DataIC50:  440nMAssay Description:Inhibition of Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and [32P]-ATPMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50484527(CHEMBL1928286)
Affinity DataKd:  470nMAssay Description:Binding affinity to Escherichia coli HPPK using 6-hydroxymethyl-7,8-dihydropterin as substrate and ATP by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50484527(CHEMBL1928286)
Affinity DataKd:  470nMAssay Description:Binding affinity to Escherichia coli HPPKMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed