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Found 2 Enz. Inhib. hit(s) with Target = '72 kDa type IV collagenase' and Ligand = 'BDBM50063166'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50063166((R)-3-(1H-Indol-3-yl)-2-(4'-methoxy-biphenyl-4-sul...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate measured up to 120 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50063166((R)-3-(1H-Indol-3-yl)-2-(4'-methoxy-biphenyl-4-sul...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed