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Found 3 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM39862'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM39862(Deprenyl | METHYL-(1-METHYL-2-PHENYL-ETHYL)-PROP-2...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM39862(Deprenyl | METHYL-(1-METHYL-2-PHENYL-ETHYL)-PROP-2...)
Affinity DataIC50:  19.6nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Government College University

Curated by ChEMBL
LigandPNGBDBM39862(Deprenyl | METHYL-(1-METHYL-2-PHENYL-ETHYL)-PROP-2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed