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Found 2 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50214744'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50214744((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation by thioflavin T-based fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50214744((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic aci...)
Affinity DataIC50:  2.26E+5nMAssay Description:Inhibition of human biotinylated amyloid beta (1 to 42) oligomerization assessed as decrease in oligomer abundance measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed