Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with Target = 'B2 bradykinin receptor' and Ligand = 'BDBM50067301'
TargetB2 bradykinin receptor(Cavia porcellus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067301((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichlo...)
Affinity DataIC50:  0.460nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067301((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichlo...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067301((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichlo...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067301((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichlo...)
Affinity DataIC50:  0.460nMAssay Description:Concentration required to inhibit specific binding of [ 3H]BK (0.06 nM) to Bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067301((E)-3-(6-Acetylamino-pyridin-3-yl)-N-({[2,4-dichlo...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]bradykinin from human recombinant B2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed