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Found 6 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50196661'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50196661(12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50196661(12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50196661(12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of sEH (unknown origin) using PHOME as substrate after 40 mins by fluorescence photometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50196661(12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of sEH (unknown origin) assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate measured after 40 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50196661(12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of mouse soluble epoxide hydrolase by spectrometric based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50196661(12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human soluble epoxide hydrolase by spectrometric based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed