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Found 5 Enz. Inhib. hit(s) with Target = 'Bifunctional epoxide hydrolase 2' and Ligand = 'BDBM50241116'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50:  1nMAssay Description:Inhibition of sEH in human HepG2 cells using 14(15)-EET-d11 as substrate assessed as reduction in conversion of 14(15)-EET-d11 to 14(15)-DHET-d11 pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory activity against Dihydrofolate reductase in Neisseria gonorrhoeaeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed