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Found 2 Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM138494'
TargetCathepsin K(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138494(US8877775, 4 | US9073869, 4)
Affinity DataIC50:  6.30E+3nMT: 2°CAssay Description:To activate the proenzyme, 5 ul procathepsin K were mixed with 1 ul activation buffer, and incubated at room temperature for 30 min.5 uL test compoun...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138494(US8877775, 4 | US9073869, 4)
Affinity DataIC50:  6.30E+3nMpH: 3.5 T: 2°CAssay Description:The following buffers were used: Activation buffer: 32.5 mM sodium acetate, adjusted to pH 3.5 with HCl; Assay buffer: 150 mM sodium acetate, 4mM EDT...More data for this Ligand-Target Pair
In DepthDetails US Patent