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Found 2 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8' and Ligand = 'BDBM50532627'
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of CDK8 in IFN-gamma-induced human HCT116 cells assessed as suppression of STAT1 phosphorylation at serine727 residue incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed