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Found 3 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2B6' and Ligand = 'BDBM50237535'
TargetCytochrome P450 2B6(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50237535(6-Paradol | CHEBI:10137 | CHEMBL2071440)
Affinity DataIC50:  6.20E+3nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50237535(6-Paradol | CHEBI:10137 | CHEMBL2071440)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 20 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50237535(6-Paradol | CHEBI:10137 | CHEMBL2071440)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes assessed as enzyme-mediated metabolite formation using bupropion as substrate incubated for 5 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed