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Found 3 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM435762'
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM435762(2-(2,6-dichlorophenyl)-1- ((1S,3R)-5-(1-ethyl-1H- ...)
Affinity DataEC50:  172nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM435762(2-(2,6-dichlorophenyl)-1- ((1S,3R)-5-(1-ethyl-1H- ...)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human D1 receptor in HEK293 cells assessed as increase in cyclic AMP production measured after 60 mins in presence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM435762(2-(2,6-dichlorophenyl)-1- ((1S,3R)-5-(1-ethyl-1H- ...)
Affinity DataEC50:  172nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed