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Found 6 Enz. Inhib. hit(s) with Target = 'D-amino-acid oxidase' and Ligand = 'BDBM23174'
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM23174(6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...)
Affinity DataIC50:  17.2nMAssay Description:Inhibition of human recombinant DAAO expressed in Escherichia coli assessed as H2O2 production from D-serine degradation after 30 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Sus scrofa (pig))
Mgi Pharma

LigandPNGBDBM23174(6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...)
Affinity DataIC50:  188nMpH: 8.5 T: 2°CAssay Description:D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM23174(6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...)
Affinity DataIC50:  507nMAssay Description:Inhibition of human DAOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM23174(6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...)
Affinity DataKd:  18nMAssay Description:Binding affinity to human recombinant DAAO by steady state study scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM23174(6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...)
Affinity DataKd:  14nMAssay Description:Binding affinity to human recombinant DAAO by isothermal titration calorimeter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Abbott Healthcare Products

Curated by ChEMBL
LigandPNGBDBM23174(6-chloro-1,2-benzoxazol-3-ol | 6-chlorobenzo[d]iso...)
Affinity DataKd:  13nMAssay Description:Binding affinity to human recombinant DAAO by kinetic study scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed