Found 3 Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50272089' TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human DGAT1 expressed in insect cell membranes using diacylglycerol/[14C]-oleoyl-CoA as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Inhibition of DGAT1 in human HEK293 cells using [13C18]oleic acid as substrate assessed as decrease in triacylglycerol synthesis preincubated for 15 ...More data for this Ligand-Target Pair
