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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM134285'
TargetDihydrofolate reductase(Streptococcus pyogenes)
University of Connecticut

US Patent
LigandPNGBDBM134285(US8853228, 146)
Affinity DataIC50:  26nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
University of Connecticut

US Patent
LigandPNGBDBM134285(US8853228, 146)
Affinity DataIC50:  67nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

US Patent
LigandPNGBDBM134285(US8853228, 146)
Affinity DataIC50:  100nMAssay Description:Heterocyclic analogs of propargyl-linked inhibitors of the third generation analogs were evaluated in enzyme inhibition assays, assessed for S. aur...More data for this Ligand-Target Pair
In DepthDetails US Patent