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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50059929'
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059929(8-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine | 8-...)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50059929(8-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine | 8-...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059929(8-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine | 8-...)
Affinity DataIC50:  2.52E+5nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50059929(8-(3,4-Dichloro-phenyl)-9H-purine-2,6-diamine | 8-...)
Affinity DataIC50:  2.52E+5nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed