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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50135142'
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135142(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pyrido[2,3-...)
Affinity DataIC50:  450nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135142(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pyrido[2,3-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of rat liver DHFR assessed as reduction in consumption of NADPH using DHFA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135142(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pyrido[2,3-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of dihydrofolate reductase from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135142(6-[(2,5-Dimethoxy-phenylamino)-methyl]-pyrido[2,3-...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed