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Found 4 Enz. Inhib. hit(s) with Target = 'Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A' and Ligand = 'BDBM60812'
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Boston College

LigandPNGBDBM60812(BDBM86641 | US9173884, BC11-28)
Affinity DataIC50:  110nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Boston College

LigandPNGBDBM60812(BDBM86641 | US9173884, BC11-28)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at mu opioid receptor in Hartley guinea pig ileum myenteric plexus longitudinal muscle assessed as effect on endomorphin 2-induce...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Boston College

LigandPNGBDBM60812(BDBM86641 | US9173884, BC11-28)
Affinity DataIC50:  110nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Boston College

LigandPNGBDBM60812(BDBM86641 | US9173884, BC11-28)
Affinity DataIC50:  110nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed