Found 4 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50069799'
Affinity DataKi: 0.130nM ΔG°: -55.5kJ/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Displacement of fluorescent F4 peptide from MDM2 (1 to 125 residues) (unknown origin) expressed in Escherichia coli by fluorescence polarization assa...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Displacement of 5-FAM labeled PMDM6-F from GST-tagged human recombinant MDM2 (1 to 118 residues) expressed in Escherichia coli incubated for 0.5 hrs ...More data for this Ligand-Target Pair