Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Endothelin receptor type B' and Ligand = 'BDBM50124446'
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124446(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124446(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]-ET-1 from human ETB receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124446(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]-ET-1 from human ETB receptor expressed in CHO cell membranes after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed