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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM19442'
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)
Affinity DataIC50:  21.5nMpH: 7.5 T: 22°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)
Affinity DataIC50:  42nMAssay Description:Displacement of [3H]-E2 from estrogen receptor-alpha (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19442(2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)p...)
Affinity DataEC50:  0.200nMAssay Description:Induction of estrogen receptor-alpha degradation in human MCF7 cells after 4 hrs by in-cell western assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed