Found 7 Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 2' and Ligand = 'BDBM403752' TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataKi: 479nMAssay Description:Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 525nMAssay Description:Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: <200nMAssay Description:The assay was used to determine the activity of the compounds of the invention. The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM ...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: <200nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: <200nMAssay Description:The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: <200nMAssay Description:The assay was used to determine the activity of the compounds of the invention.The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM N...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University Of Southern Denmark
Curated by ChEMBL
University Of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 1.23E+3nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
