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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'GTPase KRas [1-169,G12C,C118A]' and Ligand = 'BDBM515907'
Target
GTPase KRas [1-169,G12C,C118A]
(Homo sapiens (Human))
Amgen
US Patent
Ligand
BDBM515907
(2-(5-Chloro-2-ethyl-3- ((5-methoxy-3,4-dihydro- 2(...)
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Affinity Data
IC50: 150nM
Assay Description:
Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and C118A amino acid substitutions and an N-terminal His-tag, was pre-incubated in a...
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Target Info
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Ligand Info
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Details
US Patent
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