Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50124597'
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  18nMAssay Description:Transcriptional repression in HepG2 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  35nMAssay Description:Transcriptional activation in CV-1 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  85nMAssay Description:Inhibition of concanavalin A stimulated rat splenocyte proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50124597(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Affinity DataEC50:  563nMAssay Description:Inhibition of concanavalin A stimulated T-cell proliferation in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed