Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase' and Ligand = 'BDBM98185'
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98185(US8486940, 60 | US9650362, 60)
Affinity DataKi:  149nM IC50:  882nMAssay Description:Spectrophotometic Assay: This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98185(US8486940, 60 | US9650362, 60)
Affinity DataKi:  149nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM98185(US8486940, 60 | US9650362, 60)
Affinity DataIC50:  882nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails US Patent