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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM405274'
TargetGonadotropin-releasing hormone receptor(Rabbit)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 0.570nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 4.95nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 4.95nMAssay Description:Human: Test Example 1. Human GnRHr (GnRH Receptor) Activity Assay of the Present Compounds.In vitro GnRHr protein activity was tested by the followin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent