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Found 3 Enz. Inhib. hit(s) with Target = 'Heparanase' and Ligand = 'BDBM50175811'
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175811(CHEMBL200215 | N-(4-{[4-(1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant HPSE GS3 (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 based colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed