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Found 3 Enz. Inhib. hit(s) with Target = 'Heparanase' and Ligand = 'BDBM50175932'
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  75nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50:  560nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed