Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50321465'
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321465((6-(3-chlorophenoxy)pyridin-3-yl)(4-cyclobutyl-1,4...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321465((6-(3-chlorophenoxy)pyridin-3-yl)(4-cyclobutyl-1,4...)
Affinity DataKi:  15nMAssay Description:Binding affinity to histamine H3 receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321465((6-(3-chlorophenoxy)pyridin-3-yl)(4-cyclobutyl-1,4...)
Affinity DataKd:  5.01nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed