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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM117170'
TargetHistone deacetylase 1(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117170(US8648092, 101)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of recombinant human GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells Fluor-de-lys as substrate measured after 2 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117170(US8648092, 101)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent