Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50400781'
TargetHistone-lysine N-methyltransferase EZH2(Human)
UNC Eshelman School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400781BDBM50400781(CHEMBL2204997)
Affinity DataIC50: 10nMAssay Description:Inhibition of EZH2 methyltransferase activity (unknown origin) in PRC2 complex using 3H-SAM as substrate by Scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
UNC Eshelman School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400781BDBM50400781(CHEMBL2204997)
Affinity DataIC50: 79nMAssay Description:Inhibition of EZH2-mediated proliferation of human LNCaP cells after 6 days by chemiluminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed